SB 209670
- CAS No.
- 157659-79-5
- Chemical Name:
- SB 209670
- Synonyms
- SB 209670;SB209670,SB 209670;SB209670, CID108002;SB-209670, 10 mM in DMSO;(1S,2R,3S)-1-(1,3-BENZODIOXOL-5-YL)-3-[2-(CARBOXYMETHYLOXY)-4-METHOXYPHENYL]-5-PROPOXY-2,3-DIHYDRO-1H-INDENE-2-CARBOXYLIC ACID;1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-[2-(carboxymethoxy)-4-methoxyphenyl]-2,3-dihydro-5-propoxy-, (1S,2R,3S)-
- CBNumber:
- CB01379859
- Molecular Formula:
- C29H28O9
- Molecular Weight:
- 520.53
- MDL Number:
- MOL File:
- 157659-79-5.mol
- MSDS File:
- SDS
| FDA UNII | 0I32BCL40Z |
|---|
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
SB 209670 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0014952 | SB-209670 | 157659-79-5 | 1mg | $619 | 2026-06-04 | Buy |
| aablocks | AA01R5CC | SB-209670 | 157659-79-5 | 1mg | $300 | 2026-05-31 | Buy |
| aablocks | AA01R5CC | SB-209670 | 157659-79-5 | 5mg | $683 | 2026-05-31 | Buy |
| aablocks | AA01R5CC | SB-209670 | 157659-79-5 | 10mg | $924 | 2026-05-31 | Buy |
| aablocks | AA01R5CC | SB-209670 | 157659-79-5 | 25mg | $1292 | 2026-05-31 | Buy |
SB 209670 Chemical Properties, Uses, Production
Uses
SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty[1].
References
[1] E H Ohlstein, et al. SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8052-6. DOI:10.1073/pnas.91.17.8052
SB 209670 Preparation Products And Raw materials
Raw materials
Preparation Products
SB 209670 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Yaoyan Pharmaceutical Co., Ltd. | jnyaoyan@163.com | China | 3057 | 58 | |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| JinOu Biomedical (Nanjing) Co., Ltd. | 13000000000 | jinoupharma@163.com | China | 11706 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
