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E2730

E2730 Structure
E2730 structure
CAS No.
1520073-91-9
Chemical Name:
E2730
Synonyms
E2730;Sulfamide, N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]-
CBNumber:
CB014133752
Molecular Formula:
C9H8F4N2O2S
Molecular Weight:
284.23
MDL Number:
MOL File:
1520073-91-9.mol
MSDS File:
SDS
Last updated:2026-05-11 16:31:51
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E2730 Properties

Boiling point 367.340±52.00 °C(Press: 760.00 Torr)(predicted)
Density 1.651±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 7.803±0.40(predicted)

E2730 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0892170 E2730 1520073-91-9 1mg $589 2026-06-04 Buy
ChemScene CS-0892170 E2730 1520073-91-9 5mg $1466 2026-06-04 Buy
ChemScene CS-0892170 E2730 1520073-91-9 10mg $2123 2026-06-04 Buy
ChemScene CS-0892170 E2730 1520073-91-9 25mg $3158 2026-06-04 Buy
ChemScene CS-0892170 E2730 1520073-91-9 50mg $4111 2026-06-04 Buy
Product number Packaging Price Buy
CS-0892170 1mg $589 Buy
CS-0892170 5mg $1466 Buy
CS-0892170 10mg $2123 Buy
CS-0892170 25mg $3158 Buy
CS-0892170 50mg $4111 Buy

E2730 Chemical Properties, Uses, Production

Uses

E2730 is a noncompetitive but selective inhibitor of gamma-aminobutyric acid (GABA) transporter 1 (GAT1) with orally available and antiepileptic activity. E2730-mediated GAT1 inhibition is positively correlated with environmental GABA levels and selectively inhibits GAT1-mediated GABA uptake. E2730 (5-50 mg/kg; po) in rat amygdala ignition model, and in mouse cornea ignition (5-50 mg/kg), drug resistance 6Hz-44mA has demonstrated in vivo efficacy in models of psychomotor epilepsy (5-50 mg/kg), fragile X syndrome (2.5-300 mg/kg), and Dravet syndrome (10 mg/kg, 20 mg/kg)[1].

References

[1] Fukushima K, et al. Discovery of E2730, a novel selective uncompetitive GAT1 inhibitor, as a candidate for anti-seizure medication. Epilepsia Open. 2023 Sep;8(3):834-845.. DOI:10.1002/epi4.12741

E2730 Preparation Products And Raw materials

Raw materials

Preparation Products

E2730 Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from E2730 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
E2730 pictures 2026-05-11 E2730
1520073-91-9
 $1520.00-1980.00 98.54% 10g TargetMol Chemicals Inc.
  • E2730 pictures
  • E2730
    1520073-91-9
  • $1520.00-1980.00
  • 98.54%
  • TargetMol Chemicals Inc.

E2730 Spectrum

E2730(1520073-91-9)1HNMR

1520073-91-9 (E2730) Related Search:

DHEA-S Primidone Phenelzine Sulfate Furosemide 4-Aminobutyric acid
Riluzole

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E2730 Sulfamide, N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]- 1520073-91-9