DHEA-S
- CAS No.
- 651-48-9
- Chemical Name:
- DHEA-S
- Synonyms
- Dehydroepiandrosterone Sulfate;Dehydroisoandrosterone sulfate;Prasterone sulfate;10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene;PB005;PB 005;PB-005;DHEA-S;DHEA-ST;Formylisoglutamic acid
- CBNumber:
- CB01235906
- Molecular Formula:
- C19H28O5S
- Molecular Weight:
- 368.49
- MDL Number:
- MFCD00242651
- MOL File:
- 651-48-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 468.81°C (rough estimate) |
|---|---|
| Density | 1.1763 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| Melting point | 190-192 °C |
| pka | -3.51±0.18(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | 57B09Q7FJR |
DHEA-S price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0059419 | Dehydroepiandrosterone sulfate 99.93% | 651-48-9 | 1mg | $43 | 2026-06-04 | Buy |
| ChemScene | CS-0059419 | Dehydroepiandrosterone sulfate 99.93% | 651-48-9 | 5mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0059419 | Dehydroepiandrosterone sulfate 99.93% | 651-48-9 | 10mg | $157 | 2026-06-04 | Buy |
| ChemScene | CS-0059419 | Dehydroepiandrosterone sulfate 99.93% | 651-48-9 | 25mg | $336 | 2026-06-04 | Buy |
| ChemScene | CS-0059419 | Dehydroepiandrosterone sulfate 99.93% | 651-48-9 | 50mg | $531 | 2026-06-04 | Buy |
DHEA-S Chemical Properties, Uses, Production
Uses
Dehydroepiandrosterone sulfate, a neuroactive neurosteroid, plays a major role in brain development and aging by influencing the migration of neurons, arborization of dendrites, and formation of new synapses[1][2][3].
Definition
ChEBI: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.
in vivo
DHEAS chronic administration produces a dose-dependent effect on performance[3].
| Animal Model: | Sixty-four male Sprague-Dawley rats, approximately 90 days of age (300-400 g)[3]. |
| Dosage: | 5, 10, or 20 mg/kg. |
| Administration: | Subcutaneous injection starting 7 days post-surgery and 1 h prior to all behavioral testing. |
| Result: | Significantly effective in improving latency to reach the platform as compared to injured rats receiving vehicle. |
IC 50
Human Endogenous Metabolite
References
[1] E E Baulieu, et al. Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4089-91. DOI:10.1073/pnas.95.8.4089
[2] C R Parker Jr, et al. Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging. Steroids. 1999 Sep;64(9):640-7. DOI:10.1016/s0039-128x(99)00046-x
[3] Stuart W Hoffman, et al. The delayed administration of dehydroepiandrosterone sulfate improves recovery of function after traumatic brain injury in rats. J Neurotrauma. 2003 Sep;20(9):859-70. DOI:10.1089/089771503322385791
DHEA-S Preparation Products And Raw materials
Raw materials
Preparation Products
DHEA-S Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong JunRui Pharmaceutical Co., Ltd. | 0539-5636807 15762008972 | ffeng813@163.com | China | 245 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 18080489829@163.com | China | 8379 | 60 |
| Rhawn Reagent | 400-400-1332688 18019345275 | huyue@rhawn.cn | China | 14942 | 58 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 | sales@uhnshanghai.com | China | 1983 | 58 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 17754423994 | candy@biochempartner.com | China | 3057 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29090 | 58 |
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