Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>EZH2-IN-17

EZH2-IN-17

EZH2-IN-17 Structure
EZH2-IN-17 structure
CAS No.
2489672-09-3
Chemical Name:
EZH2-IN-17
Synonyms
EZH2-IN-17;Benzamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[2,3-dihydro-1-(4-morpholinyl)-1H-inden-5-yl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-methyl-
CBNumber:
CB014256703
Molecular Formula:
C36H46N4O4
Molecular Weight:
598.78
MDL Number:
MOL File:
2489672-09-3.mol
Last updated:2025-06-29 08:01:21
Request For Quotation

EZH2-IN-17 Properties

Boiling point 778.664±60.00 °C(Press: 760.00 Torr)(predicted)
Density 1.183±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 11.793±0.10(predicted)

EZH2-IN-17 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0906329 EZH2-IN-17 98.08% 2489672-09-3 5mg $433 2026-06-04 Buy
ChemScene CS-0906329 EZH2-IN-17 98.08% 2489672-09-3 10mg $704 2026-06-04 Buy
ChemScene CS-0906329 EZH2-IN-17 98.08% 2489672-09-3 25mg $1452 2026-06-04 Buy
ChemScene CS-0906329 EZH2-IN-17 98.08% 2489672-09-3 50mg $2329 2026-06-04 Buy
Product number Packaging Price Buy
CS-0906329 5mg $433 Buy
CS-0906329 10mg $704 Buy
CS-0906329 25mg $1452 Buy
CS-0906329 50mg $2329 Buy

EZH2-IN-17 Chemical Properties, Uses, Production

Uses

EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively)[1].

References

[1] Xin Xu, et al. Conformationally constrained potent inhibitors for enhancer of zeste homolog 2 (EZH2). Bioorg Med Chem Lett. 2023 Nov 11:129558. DOI:10.1016/j.bmcl.2023.129558

EZH2-IN-17 Preparation Products And Raw materials

Raw materials

Preparation Products

2489672-09-3 (EZH2-IN-17) Related Search:

EPZ015666 GSK-3326595 UNC-0642 UNC0638 MRTX-1719
SGC0946

1of2

EZH2-IN-17 Benzamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[2,3-dihydro-1-(4-morpholinyl)-1H-inden-5-yl]-3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-2-methyl- 2489672-09-3