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HSD17B13-IN-54

HSD17B13-IN-54 structure

CAS No.: 2770247-49-7

Chemical Name:: HSD17B13-IN-54

Synonyms: HSD17B13-IN-54;Benzamide, 3,5-dichloro-N-[8-fluoro-3,4-dihydro-2-methyl-4-oxo-3-[[2-(trifluoromethyl)phenyl]methyl]-5-quinazolinyl]-4-hydroxy-

CBNumber:: CB014270055

Molecular Formula:: C24H15Cl2F4N3O3

Molecular Weight:: 540.29

MDL Number:

MOL File:: 2770247-49-7.mol

Last updated:2025-05-19 13:46:59

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HSD17B13-IN-54 Properties

Density	1.539±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	5.318±0.25(predicted)

HSD17B13-IN-54 Chemical Properties, Uses, Production

Uses

HSD17B13-IN-54 (Compound 158) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-54 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].

References

[1] Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.

HSD17B13-IN-54 Preparation Products And Raw materials

Raw materials

Preparation Products

HSD17B13-IN-54 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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HSD17B13-IN-54 Benzamide, 3,5-dichloro-N-[8-fluoro-3,4-dihydro-2-methyl-4-oxo-3-[[2-(trifluoromethyl)phenyl]methyl]-5-quinazolinyl]-4-hydroxy- 2770247-49-7