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Nav1.7 blocker 1

Nav1.7 blocker 1 structure

CAS No.: 1426336-36-8

Chemical Name:: Nav1.7 blocker 1

Synonyms: Nav1.7 blocker 1;4-Pyrimidinecarboxamide, 2-[4-(4-fluorophenoxy)phenyl]-6-[3-(hydroxymethyl)-4-morpholinyl]-

CBNumber:: CB014282254

Molecular Formula:: C22H21FN4O4

Molecular Weight:: 424.43

MDL Number:

MOL File:: 1426336-36-8.mol

Last updated:2025-04-17 18:22:24

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Nav1.7 blocker 1 Properties

Boiling point	563.4±50.0 °C(predicted)
Density	1.340±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	14.31±0.50(predicted)

Nav1.7 blocker 1 Chemical Properties, Uses, Production

Uses

Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1].

References

[1] Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07

Nav1.7 blocker 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Nav1.7 blocker 1 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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Nav1.7 blocker 1 4-Pyrimidinecarboxamide, 2-[4-(4-fluorophenoxy)phenyl]-6-[3-(hydroxymethyl)-4-morpholinyl]- 1426336-36-8