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3-Amino-2-bromo-4-methoxypyridine

CAS No.
109613-97-0
Chemical Name:
3-Amino-2-bromo-4-methoxypyridine
Synonyms
2-BroMo-4-Methoxypyridin-3-aMine;3-Amino-2-bromo-4-methoxypyridine;3-Pyridinamine, 2-bromo-4-methoxy-;2-Bromo-4-methoxy-pyridin-3-ylamine
CBNumber:
CB01471175
Molecular Formula:
C6H7BrN2O
Molecular Weight:
203.04
MDL Number:
MOL File:
109613-97-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:43
Product description Number Pack Size Price
2-Bromo-4-methoxypyridin-3-amine 97% AS114325 1g $171
2-Bromo-4-methoxypyridin-3-amine 97% AS114325 5g $613
2-Bromo-4-methoxypyridin-3-amine 303015 250.00mg $62
2-Bromo-4-methoxypyridin-3-amine 303015 1.00g $113
2-Bromo-4-methoxypyridin-3-amine 303015 5.00g $426

3-Amino-2-bromo-4-methoxypyridine Properties

Boiling point 305.7±37.0 °C(Predicted)
Density 1.622±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 3.02±0.18(Predicted)
Appearance Off-white to light yellow Solid

3-Amino-2-bromo-4-methoxypyridine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS114325 2-Bromo-4-methoxypyridin-3-amine 97% 109613-97-0 1g $171 2026-06-04 Buy
Activate Scientific AS114325 2-Bromo-4-methoxypyridin-3-amine 97% 109613-97-0 5g $613 2026-06-04 Buy
Matrix Scientific 303015 2-Bromo-4-methoxypyridin-3-amine 109613-97-0 250.00mg $62 2026-05-19 Buy
Matrix Scientific 303015 2-Bromo-4-methoxypyridin-3-amine 109613-97-0 1.00g $113 2026-05-19 Buy
Matrix Scientific 303015 2-Bromo-4-methoxypyridin-3-amine 109613-97-0 5.00g $426 2026-05-19 Buy
Product number Packaging Price Buy
AS114325 1g $171 Buy
AS114325 5g $613 Buy
303015 250.00mg $62 Buy
303015 1.00g $113 Buy
303015 5.00g $426 Buy

3-Amino-2-bromo-4-methoxypyridine Chemical Properties,Uses,Production

Synthesis

3-AMINO-4-METHOXYPYRIDINE

33631-09-3

3-Amino-2-bromo-4-methoxypyridine

109613-97-0

General procedure for the synthesis of 3-amino-2-bromo-4-methoxypyridine from 3-amino-4-methoxypyridine: To a concentrated solution of 3-amino-4-methoxypyridine (6.76 g, 54.5 mmol) in hydrochloric acid (50 mL), bromine (3.36 mL, 65.4 mmol) was added dropwise over a period of 30 seconds. The reaction mixture was stirred at room temperature for 1 hour and subsequently heated at 55 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and poured into ice water. The pH of the solution was adjusted to alkaline with ammonium hydroxide. The resulting suspension was partitioned between water and ethyl acetate. The organic and aqueous layers were separated and the aqueous layer was extracted with ethyl acetate (2×). The organic layers were combined, washed sequentially with water and brine, dried over magnesium sulfate, filtered, and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent ethyl acetate/methanol (100/0 to 80/20) to afford 9.18 g of the target product in white powder form (82% yield). Product characterization data: 1H NMR (CDCl3, 300 MHz) δ 7.75 (d, J = 5.3 Hz, 1H), 6.68 (d, J = 5.3 Hz, 1H), 3.91 (s, 3H); LC Rt: 0.89 min; LCMS m/z 203 ([M+H]+, 100%).

References

[1] Patent: WO2011/78984, 2011, A1. Location in patent: Page/Page column 62; 63
[2] Liebigs Annalen der Chemie, 1987, p. 857 - 862
[3] Patent: US2016/176871, 2016, A1. Location in patent: Paragraph 0924-0925
[4] Patent: US2015/94328, 2015, A1. Location in patent: Paragraph 0450-0453
[5] Patent: WO2015/49574, 2015, A1. Location in patent: Page/Page column 53; 54

3-Amino-2-bromo-4-methoxypyridine Preparation Products And Raw materials

3-Amino-2-bromo-4-methoxypyridine Suppliers

Global( 43)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49969 58
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13523716970 Lingzhiyue@aliyun.com China 3145 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd.
+8618118463618 sales1@artkmedchem.com China 39021 58
Cochemical Co. Ltd.
+86-029-86115547 +86-17791676824 sales@cochemical.com China 3952 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Gihi Chemicals Co., Limited +86-0571-86217390 +8618058761490 info@gihichem.com China 998 58
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3989 55
SynAsst Chemical. 021-60343070 China 12740 55

3-Amino-2-bromo-4-methoxypyridine Spectrum

2-Bromo-4-methoxy-pyridin-3-ylamine 3-Amino-2-bromo-4-methoxypyridine 2-BroMo-4-Methoxypyridin-3-aMine 3-Pyridinamine, 2-bromo-4-methoxy- 109613-97-0