[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
- CAS No.
- 66722-57-4
- Chemical Name:
- [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
- Synonyms
- Bisoprolol Impurity 8;Bisoprolol Impurity 20;Bisoprolol intermediate;Bisoprolol epoxide impurities;2-[4-(2-Isopropoxyethoxymethyl)phen;Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane;[[4-[[2-Isopropoxyethoxy]methyl]phenoxy]methyl]oxirane;[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxi;2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane;[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane
- CBNumber:
- CB01564879
- Molecular Formula:
- C15H22O4
- Molecular Weight:
- 266.33
- MDL Number:
- MFCD12024632
- MOL File:
- 66722-57-4.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane | TRC-M304765-25MG | 25mg | $186 |
| [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane | TRC-M304765-250MG | 250mg | $1375 |
| 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | FI178180 | 0.025g | $150 |
| 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | FI178180 | 0.01g | $150 |
| 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | FI178180 | 0.05g | $178.48 |
| More product size | |||
| Boiling point | 362.6±22.0 °C(Predicted) |
|---|---|
| Density | 1.084±0.06 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Methanol (Sparingly) |
| form | Oil |
| color | Colourless |
| CAS DataBase Reference | 66722-57-4 |
| FDA UNII | MFA9B358BM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS08,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H341-H351-H302-H317-H332 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501 |
| REACH Registrations | Active |
[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-M304765-25MG | [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane | 66722-57-4 | 25mg | $186 | 2026-06-03 | Buy |
| TRC | TRC-M304765-250MG | [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane | 66722-57-4 | 250mg | $1375 | 2026-06-03 | Buy |
| Biosynth | FI178180 | 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | 66722-57-4 | 0.025g | $150 | 2026-06-04 | Buy |
| Biosynth | FI178180 | 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | 66722-57-4 | 0.01g | $150 | 2026-06-04 | Buy |
| Biosynth | FI178180 | 2-((4-((2-Isopropoxyethoxy)methyl)phenoxy)methyl)oxirane | 66722-57-4 | 0.05g | $178.48 | 2026-06-04 | Buy |
[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Oil
Uses
An intermediate for the synthesis of Bisoprolol.
Synthesis
The synthesis of 4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane is as follows: steps. 1) Preparation of 4-hydroxybenzyl alcohol: 4-Hydroxybenzaldehyde is reduced with NaBH4. Work-up yields the product. 2) Preparation of 4-[(2-isopropoxyethoxy)methyl]phenol: 4-Hydroxybenzyl alcohol reacts with 2-isopropoxyethanol catalyzed by Amberlyst-15 resin. Work-up gives the product. 3) Preparation of the title oxirane derivative: The sodium salt of the phenol from step 2 reacts with epichlorohydrin. Toluene extraction is performed. The organic phase is treated with solid NaOH, washed, and distilled to an oil. High-vacuum distillation purifies the product.
[[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-18627948422 | sale@hdimpurity.com | China | 3676 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1796 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9389 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
View Lastest Price from [[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]methyl]oxirane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-12 | Bisoprolol Impurity 29
66722-57-4
|
10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
![]() |
2019-12-27 | 2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane
66722-57-4
|
$2.00 | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-

- Bisoprolol Impurity 29
66722-57-4
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
![2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/e6216169-caf9-4b02-b77b-872a285b021e.png)
- 2-[[4-(2-propan-2-yloxyethoxymethyl)phenoxy]methyl]oxirane
66722-57-4
- $2.00
- ≥98%
- Career Henan Chemical Co
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