2,3-Dichloro-5-formylpyridine
- CAS No.
- 71690-05-6
- Chemical Name:
- 2,3-Dichloro-5-formylpyridine
- Synonyms
- 2,3-Dichloro-5-formylpyridine;5,6-DICHLOROPYRIDINE-3-CARBALDEHYDE;5,6-Dichloropyridyl-3-carboxaldehyde;5,6-Dichloro-3-pyridinecarboxaldehyde;5,6-Dichloropyridine-3-carboxaldehyde;3-Pyridinecarboxaldehyde, 5,6-dichloro-;2,3-DICHLORO-5-FORMYLPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB0172943
- Molecular Formula:
- C6H3Cl2NO
- Molecular Weight:
- 176
- MDL Number:
- MFCD08448226
- MOL File:
- 71690-05-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
2,3-Dichloro-5-formylpyridine price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS33879 | 2,3-Dichloro-5-formylpyridine 96% | 71690-05-6 | 1g | $166 | 2026-06-04 | Buy |
| Activate Scientific | AS33879 | 2,3-Dichloro-5-formylpyridine 96% | 71690-05-6 | 5g | $525 | 2026-06-04 | Buy |
| Activate Scientific | AS33879 | 2,3-Dichloro-5-formylpyridine 96% | 71690-05-6 | 25g | $1414 | 2026-06-04 | Buy |
| Matrix Scientific | 302444 | 5,6-Dichloronicotinaldehyde | 71690-05-6 | 250.00mg | $52 | 2026-05-19 | Buy |
| Matrix Scientific | 302444 | 5,6-Dichloronicotinaldehyde | 71690-05-6 | 1.00g | $63 | 2026-05-19 | Buy |
2,3-Dichloro-5-formylpyridine Chemical Properties,Uses,Production
Uses
5,6-Dichloropyridyl-3-carboxaldehyde is used to prepare [(pyridyl)piperazinyl]benzimidazoles analogs as potent, orally available antagonists of the transient receptor potential vanilloid 1 and analgesics. It is also used to synthesize heterocyclic aryl isoxazolines with insecticidal activities.
Synthesis
54127-30-9
71690-05-6
General procedure for the synthesis of 2,3-dichloro-5-formylpyridine from 5,6-dichloro-3-pyrimidinemethanol: To a 500 mL round-bottomed flask was added an anhydrous dichloromethane (150 mL) solution of 2,3-dichloro-5-hydroxymethylpyridine (64.810 g, 50.0 mmol), followed by manganese oxide (43.5 g, 0.50 mol). The reaction mixture was stirred at 25 °C for 48 hours. Upon completion of the reaction, it was filtered through Celite and the filtrate was concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography using ethyl acetate (0%-40%)/hexane gradient elution to afford 2,3-dichloro-5-formylpyridine (7.2 g, 90% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3): δ10.08 (1H, s), 8.77 (1H, d, J=1.97 Hz), 8.25 (1H, d, J=1.97 Hz). the LC/MS analysis showed the molecular ion peak (M+1) was 176.
References
[1] Patent: US2010/120862, 2010, A1. Location in patent: Page/Page column 94
[2] Patent: US2010/137306, 2010, A1. Location in patent: Page/Page column 169
[3] Patent: US2010/130499, 2010, A1. Location in patent: Page/Page column 122
[4] Patent: WO2008/132600, 2008, A2. Location in patent: Page/Page column 258
[5] Patent: WO2008/133973, 2008, A1. Location in patent: Page/Page column 68-69
2,3-Dichloro-5-formylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Hebei Summedchem Co.,Ltd | 0319-5801333-8008 15630992918 | sales@summedchem.com | China | 1000 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
View Lastest Price from 2,3-Dichloro-5-formylpyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 2,3-DICHLORO-5-FORMYLPYRIDINE
71690-05-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-03-20 | 2,3-DICHLORO-5-FORMYLPYRIDINE
71690-05-6
|
$1.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 2,3-DICHLORO-5-FORMYLPYRIDINE
71690-05-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2,3-DICHLORO-5-FORMYLPYRIDINE
71690-05-6
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
