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ChemicalBook >> CAS DataBase List >>ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Structure
ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate structure
CAS No.
31686-94-9
Chemical Name:
ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate
Synonyms
Ethyl 4-(4-fluorophenyl);Ethyl 4-fluoro-a,g-dioxo-benzenebutanoate;ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate;ethyl 2,4-dioxo-4-(4-fluorophenyl)butanoate;ETHYL-4-(4-FLOURO PHENYL)-2,4-DI OXO BUTANOATE;Benzenebutanoicacid,4-fluoro-α,γ-dioxo-,ethylester;Benzenebutanoic acid, 4-fluoro-α,γ-dioxo-, ethyl ester;4-(4-Fluoro-phenyl)-2,4-dioxo-butyric acid ethyl ester;Benzenebutanoic acid, 4-fluoro-.alpha.,.gaMMa.-dioxo-, ethyl ester
CBNumber:
CB01791330
Molecular Formula:
C12H11FO4
Molecular Weight:
238.21
MDL Number:
MFCD02672449
MOL File:
31686-94-9.mol
MSDS File:
SDS
Last updated:2026-05-27 17:20:55
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ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Properties

Boiling point 360.9±22.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 6.00±0.25(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 093900 Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 31686-94-9 250.00mg $284 2026-05-18 Buy
Matrix Scientific 093900 Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 31686-94-9 1.00g $639 2026-05-18 Buy
Synthonix E55694 Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 98% 31686-94-9 100mg $53 2026-05-06 Buy
Synthonix E55694 Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 98% 31686-94-9 250mg $58 2026-05-06 Buy
Synthonix E55694 Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 98% 31686-94-9 1g $60 2026-05-06 Buy
Product number Packaging Price Buy
093900 250.00mg $284 Buy
093900 1.00g $639 Buy
E55694 100mg $53 Buy
E55694 250mg $58 Buy
E55694 1g $60 Buy

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Chemical Properties, Uses, Production

Synthesis

4-Fluoroacetophenone

403-42-9

Diethyl oxalate

95-92-1

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

31686-94-9

Synthesis of ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate: In a 2L round-bottomed flask fitted with a reflux condenser tube and a CaCl2 drying tube, sodium metal (49.9 g, 2.17 mol, 3.0 eq.) was slowly dissolved in ethanol (1.0 L). After the resulting sodium ethanol solution was cooled to about 10°C, a mixture of 4-fluoroacetophenone (100.0 g, 0.72 mol) and diethyl oxalate (295 mL, 2.17 mol, 3.0 eq.) was slowly added. The reaction mixture was stirred for about 15 minutes and then placed in a refrigerator to stand overnight. Subsequently, the reaction mixture was poured into a mixture consisting of concentrated hydrochloric acid solution (300 mL) and ice (about 1 kg). The resulting precipitate was collected by filtration and washed with plenty of water and finally dried in a vacuum dryer using P2O5/KOH. The product was a light yellow powder, yield: 165.5 g (96% yield).

References

[1] Patent: WO2015/95337, 2015, A2. Location in patent: Paragraph 0030
[2] Synthetic Communications, 2013, vol. 43, # 1, p. 110 - 117
[3] Patent: WO2015/196071, A1. Location in patent: Paragraph 0520
[3] Patent: , 2015, . Location in patent: Paragraph 0520
[5] Patent: WO2017/40606, 2017, A1. Location in patent: Paragraph 0465

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate synthesis

403-42-9
95-92-1
31686-94-9
Synthesis of ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate from 4-Fluoroacetophenone and Diethyl oxalate

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Preparation Products And Raw materials

Raw materials

4-Fluoroacetophenone Diethyl oxalate

Preparation Products

5-(4-fluorophenyl)-1H-pyrazole-3-carbaldehyde

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Suppliers

Global Suppliers ( 53)
Supplier Tel Email Country ProdList Advantage
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3980 55
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9780 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9711 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Nanjing BAM Biomedical Technology Co., Ltd. 18066080842 13952020641 bamd@foxmail.com China 774 55
Supplier Advantage
Wuhan TCASChem Technology Co., Ltd. 55
Amatek Scientific Co. Ltd. 55
Bide Pharmatech Ltd. 60
Yancheng KangdiSen Pharmaceutical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Amadis Chemical Company Limited 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Nanjing BAM Biomedical Technology Co., Ltd. 55

View Latest Price from ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate pictures 2025-04-02 ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate
31686-94-9
 200kg 0.99 20 tons Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate pictures 2024-07-21 ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate
31686-94-9
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Spectrum

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate(31686-94-9)1HNMR

31686-94-9 (ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate) Related Search:

Ethyl 2,4-dioxo-4-phenylbutanoate Ethyl 4-(4-chlorophenyl)-2,4-dioxobutanoate ethyl 4-(2,4-difluorophenyl)-2,4-dioxobutanoate Ethyl 3-fluoro-a,g-dioxo-benzenebutanoate Ethyl 3,4-difluoro-α,γ-dioxobenzenebutanoate
Methyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

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ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate Benzenebutanoic acid, 4-fluoro-.alpha.,.gaMMa.-dioxo-, ethyl ester Ethyl 4-fluoro-a,g-dioxo-benzenebutanoate Ethyl 4-(4-fluorophenyl) 4-(4-Fluoro-phenyl)-2,4-dioxo-butyric acid ethyl ester Benzenebutanoic acid, 4-fluoro-α,γ-dioxo-, ethyl ester Benzenebutanoicacid,4-fluoro-α,γ-dioxo-,ethylester ETHYL-4-(4-FLOURO PHENYL)-2,4-DI OXO BUTANOATE ethyl 2,4-dioxo-4-(4-fluorophenyl)butanoate 31686-94-9