H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2
- CAS No.
- 109212-72-8
- Chemical Name:
- H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2
- Synonyms
- (D-Pro2,D-Trp6;DPHDFWVWL-NLE-NH2;(D-Pro?,D-Trp?·?,Nle??)-Neurokinin B;(D-PRO2,D-TRP6,8,NLE10)-NEUROKININ B;ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2;H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2;L-Norleucinamide,L-α-aspartyl-D-prolyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-D-tryptophyl-L-valyl-D-tryptophyl-L-leucyl-;L-Norleucinamide, L-α-aspartyl-D-prolyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-D-tryptophyl-L-valyl-D-tryptophyl-L-leucyl- (9CI)
- CBNumber:
- CB0194367
- Molecular Formula:
- C67H87N15O14
- Molecular Weight:
- 1326.5
- MDL Number:
- MFCD00167606
- MOL File:
- 109212-72-8.mol
Product description | Number | Pack Size | Price |
[D-PRO2, D-TRP6,8, NLE10]-NEUROKININ B 95.00% | PEP0000120 | 1MG | $679.14 |
H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 Chemical Properties,Uses,Production
Uses
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].
in vivo
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) significantly reduces Substance P- and Neurokinin B- but not acetylcholine- or Neurokinin A-induced salivation. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B lowers blood pressure in anesthetized rats by 35 to 40%[2].
References
[1] H I Jacoby, et al. Differentiation of multiple neurokinin receptors in the guinea pig ileum. Life Sci. 1986 Nov 24;39(21):1995-2003. DOI:10.1016/0024-3205(86)90323-1
[2] C W Murray, et al. Neurokinin-induced salivation in the anesthetized rat: a three receptor hypothesis. J Pharmacol Exp Ther. 1987 Aug;242(2):500-6. DOI:10.1016/0024-3205(86)90323-1
H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
Moxin Chemicals | +86-17320513646 +8617320513646 | anna@molcoo.com | China | 10000 | 58 |
GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42943 | 64 |
View Lastest Price from H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2 manufacturers
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2020-03-06 | H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2
109212-72-8
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
-
- H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2
109212-72-8
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co