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Alantolactone

CAS No.
546-43-0
Chemical Name:
Alantolactone
Synonyms
HELENINE;ALANTOLACETONE;(+)-Alantolactone;Alantolactone/Helenine;4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone;helenin;Eupatal;NSC 93131;NSC 333843;Alant camphor
CBNumber:
CB0194433
Molecular Formula:
C15H20O2
Molecular Weight:
232.32
MDL Number:
MFCD00274568
MOL File:
546-43-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
Product description Number Pack Size Price
Alantolactone ≥98% (HPLC) SML0415 5mg $124
Alantolactone ≥98% (HPLC) SML0415 25mg $486
Alantolactone phyproof? Reference Substance PHL89156 10MG $493
Alantolactone min. 95.0 % A3585 250MG $254
Alantolactone ≥98% 29762 5mg $81
More product size

Alantolactone Properties

Melting point 78-79 C
Boiling point 275 C
alpha D +175° (chloroform)
Density 1.0610 (rough estimate)
refractive index 1.4360 (estimate)
storage temp. -20°C
solubility DMSO: soluble15mg/mL (clear solution)
form powder
color white to beige
Odor Peculiar sweet-minty, slightly woody odor
InChI InChI=1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1
InChIKey PXOYOCNNSUAQNS-AGNJHWRGSA-N
SMILES O1C(=O)C(=C)[C@@]2([H])C=C3[C@@](C)(C[C@@]12[H])CCC[C@@H]3C
LogP 3.380
CAS DataBase Reference 546-43-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII M7GSN5Q1M6
UNSPSC Code 51111800
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P333+P313-P362+P364-P501
Hazard Codes  Xi
Risk Statements  36/37/38-43
Safety Statements  26-36-36/37-24/25
WGK Germany  3
HS Code  29322090
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Sens. 1

Alantolactone price More Price(89)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0415 Alantolactone ≥98% (HPLC) 546-43-0 5mg $124 2026-04-30 Buy
Sigma-Aldrich SML0415 Alantolactone ≥98% (HPLC) 546-43-0 25mg $486 2026-04-30 Buy
Sigma-Aldrich PHL89156 Alantolactone phyproof? Reference Substance 546-43-0 10MG $493 2026-04-30 Buy
TCI Chemical A3585 Alantolactone min. 95.0 % 546-43-0 250MG $254 2026-04-30 Buy
Cayman Chemical 29762 Alantolactone ≥98% 546-43-0 5mg $81 2026-04-30 Buy
Product number Packaging Price Buy
SML0415 5mg $124 Buy
SML0415 25mg $486 Buy
PHL89156 10MG $493 Buy
A3585 250MG $254 Buy
29762 5mg $81 Buy

Alantolactone Chemical Properties,Uses,Production

Description

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone-mix, used to detect sensitization to Compositae.

Chemical Properties

Crystalline powder

Uses

anthelmintic, antibacterial, antineoplastic

Uses

Alantolactone is sesquiterpene lactone that possesses anti-inflammatory property. Alantolactone have been studied to be developed as a novel agent against human liver cancer.

Uses

Alantolactone has been used:

  • in cell viability assay
  • to examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)
  • in assessment of degranulation

Definition

ChEBI: A sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

Contact allergens

The allergen eudesmanolide sesquiterpene lactone was isolated from elecampane (Inula helenium L.). With dehydrocostuslactone and costunolide, it is a component of the (sesquiterpene) lactone mix used to detect sensitization to Compositae-Asteraceae.

Solubility in organics

Soluble in alcohol and essential oils

storage

Store at -20°C

Alantolactone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 341)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29766 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +86-18080483897 sales@biopurify.com China 4616 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
TargetMol Chemicals Inc.
+1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Apeloa Pharmaceutical Co., Ltd.
+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1478 58
Dideu Industries Group Limited
+8617392712697 1022@dideu.com China 29095 58
Baoji Guokang Healthchem Co., Ltd.
+86-0917-3909592 +86-13892490616 gksales1@gk-bio.com China 9036 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58

View Lastest Price from Alantolactone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Alantolactone pictures 2026-07-27 Alantolactone
546-43-0
$50.00-144.00 99.91% 10g TargetMol Chemicals Inc.
Alantolactone pictures 2024-04-12 Alantolactone
546-43-0
1kg 98% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Alantolactone pictures 2024-04-02 Alantolactone
546-43-0
$580.00 1g 97 500 Kg R&D Scientific Inc.
  • Alantolactone pictures
  • Alantolactone
    546-43-0
  • $50.00-144.00
  • 99.91%
  • TargetMol Chemicals Inc.
  • Alantolactone pictures
  • Alantolactone
    546-43-0
  • $0.00
  • 98%
  • Shaanxi Haibo Biotechnology Co., Ltd

Alantolactone Spectrum

HELENINE 8b-hydroxy-4ah-eudesm-5-en-12-oic acid ALLANTOLACTONE ALANTOLACETONE ALANTOLACTONE [3ar-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho-[2,3-b]furan-2(3h)-one [3aR-(3aalpha,5beta,8abeta,9aalpha)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one Alantolactone (Helenin) helenin 4αH-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone (8CI) Alant camphor Alantolactone (6CI) Elecampane camphor Eupatal Helenin (7CI) Inula camphor Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)- Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, [3aR-(3aα,5β,8aβ,9aα)]- NSC 93131 8b-hydroxy-4aH-eudesm-s-en-12-oic acid Naphtho[2,3-b]furan-2(3H)-one,3a,5,6,7,8,8a,9,9a- octahydro-5,8a-dimethyl-3-methylene-,(3aR,5S,8aR,9aR)- 4a.H-Eudesma-5,11(13)-dien-12-oic acid, 8b-hydroxy-, g-lactone (3aR)-3a,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one (3aR)-3aα,5,6,7,8,8a,9,9aα-Octahydro-5β,8aβ-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one ALANTOLACTONE(RG) Alantolactone/Helenine Alantic anhydride NSC 333843 3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylene-naphtho[2,3-b]furan-2(3H)-one Alantolactone, 98%, from Inula helenium L. (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one Alantolactone USP/EP/BP Alantolactone Inula camphor 3aR-(3a?,5?,8a?,9a?)]-3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one hymenolactone Alantolactone-RM Alantolactone, 10 mM in DMSO (3ar,5s,8ar,9ar)-5,8a-dimethyl-3-methylene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3h)-one (3a-R,5S,8a-R,9a-R)-5,8a-dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphthalenebenzo[2,3-b]furan-2(5H)-one Alantolactone (Standard) (+)-Alantolactone 546-43-0 Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Alkaloids chiral