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1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE structure

CAS No.: 287471-30-1

Chemical Name:: 1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE

Synonyms: Terbinafine Impurity 45;Terbinafine Impurity 22;1-Chloro-6,6-dimethyl-2-hepten-4-yne;2-HEPTEN-4-YNE,1-CHLORO-6,6-DIMETHYL;1-Chloro-6,6-dimethyl-2-hepten-4-ino;(E)-1-chloro-6,6-diMethylhept-2-en-4-yne;(2E)-1-chloro-6,6-dimethylhept-2-en-4-yne;1-CHLORO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE;2-HEPTEN-4-YNE, 1-CHLORO-6,6-DIMETHYL-, (2E)-

CBNumber:: CB0198486

Molecular Formula:: C9H13Cl

Molecular Weight:: 156.65

MDL Number:: MFCD04039160

MOL File:: 287471-30-1.mol

MSDS File:: SDS

Last updated:2026-05-27 22:29:58

Product description	Number	Pack Size	Price
(2E)-1-Chloro-6,6-dimethyl-2-hepten-4-yne 95%	AA002W97	25g	$12
(2E)-1-Chloro-6,6-dimethyl-2-hepten-4-yne 95%	AA002W97	100g	$38
(2E)-1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE 95.00%	HCH0036879	25G	$1404.36
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1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE Properties

Boiling point	207.5±23.0 °C(Predicted)
Density	0.946±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere, 2-8°C
InChI	InChI=1S/C9H13Cl/c1-9(2,3)7-5-4-6-8-10/h4,6H,8H2,1-3H3/b6-4+
InChIKey	ZIXABMZBMHDFEZ-GQCTYLIASA-N
SMILES	C(Cl)/C=C/C#CC(C)(C)C
CAS DataBase Reference	287471-30-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA002W97	(2E)-1-Chloro-6,6-dimethyl-2-hepten-4-yne 95%	287471-30-1	25g	$12	2026-05-28	Buy
aablocks	AA002W97	(2E)-1-Chloro-6,6-dimethyl-2-hepten-4-yne 95%	287471-30-1	100g	$38	2026-05-28	Buy
American Custom Chemicals Corporation	HCH0036879	(2E)-1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE 95.00%	287471-30-1	25G	$1404.36	2021-12-16	Buy

Product number	Packaging	Price	Buy
AA002W97	25g	$12	Buy
AA002W97	100g	$38	Buy
HCH0036879	25G	$1404.36	Buy

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE Chemical Properties,Uses,Production

Description

1-Chloro-6,6-dimethyl-2-hepten-4-yne is the allylamine antifungal agents terbinafine intermediate.1-Chloro-6,6-dimethyl-2-hepten-4-yne choose to inhibit COX-fungal squalene, so that reduction of membrane ergosterol, thus inhibiting the growth of fungi play an inhibitory role; right ergosterol synthesis of precursors and no inhibitory effect on other stages.

Uses

1-Chloro-6,6-dimethyl-2-heptene-4-yne is a hydrocarbon derivative and can be used as a pharmaceutical intermediate.

Application

1-Chloro-6,6-dimethyl-2-hepten-4-yne is a chlorinating agent that has been used to minimise hydrochloric acid by converting it to chloride. It is also used in the chlorination of magnesium and other metals. 1-Chloro-6,6-dimethyl-2-hepten-4-yne has been shown to be an effective antifungal agent against dermatophytes such as Trichophyton rubrum and Microsporum canis. The compound is toxic to humans and animals because it produces acrolein and terbinafine during chlorination. It also produces hydrochloric acid as a by-product of chlorination.

Synthesis

1-Chloro-6,6-dimethyl-2-hepten-4-yne mainly due to keratin aggregation produce squalene, was squalene cyclooxygenase inhibition, squalene in the cells of a large number gathered in the form of lipid droplets penetrate fungal cell membrane, destruction of the membrane lipid composition, resulting in fungal death. A typical procedure for preparing of 1-chloro-6,6-dimethyl-2-hepten-4-yne using boron trichloride is as follows: Compound 1 (53 g, 0.38 mol) in 2800 mL of n-hexane was cooled to 1015. Boron trichloride (1 M in hexane, 480 mL, 0.48 mol) was added to the mixture at 1520 over a 10 min period. After 10 min of stirring at 20, the mixture was quenched with 1000 mL of water and stirred for 10 min. The separated organic phase was washed with 20% NaCl, dried (MgSO4), and evaporated to afford the title compound 2 (57.1 g, 95%) in 9:1 E:Z ratio. Synthesis_287471-30-1

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE Preparation Products And Raw materials

Raw materials

Preparation Products

Terbinafine Hydrochloride

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE Suppliers

Global( 163)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
shandong perfect biotechnology co.ltd	+86-53169958659 +86-13153181156	sales@sdperfect.com	China	293	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
CD Chemical Group Limited	+86-13651442114	info@codchem.com	China	17253	58
Henan Alfa Chemical Co., Ltd	+8618339805032	sale03@alfachem.cn	China	9858	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9628	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +8619957148339	market18@leapchem.com	China	24569	58
Zhengzhou Anbu Chem Co.,Ltd	+86-0371-88006763; +86-15988602810	sales@anbuchem.com	China	5812	58

Supplier	Advantage
shandong perfect biotechnology co.ltd	58
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
BOC Sciences	58
CD Chemical Group Limited	58
Henan Alfa Chemical Co., Ltd	58
changzhou huayang technology co., ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Zhengzhou Anbu Chem Co.,Ltd	58

1-Chloro-6,6-dimethyl-2-hepten-4-yne: Uses; Preparation
1-Chloro-6,6-dimethyl-2-hepten-4-yne is the allylamine antifungal agents terbinafine intermediate.1-Chloro-6,6-dimethyl-2-hept....
Nov 1,2019

View Lastest Price from 1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-27	1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE 287471-30-1		1kg	99% HPLC	100 kgs	shandong perfect biotechnology co.ltd
2021-08-12	1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE 287471-30-1	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE 287471-30-1	$7.00	1kg	99%	100KG	Career Henan Chemical Co

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE
287471-30-1
$0.00
99% HPLC
shandong perfect biotechnology co.ltd

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE
287471-30-1
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE
287471-30-1
$7.00
99%
Career Henan Chemical Co

287471-30-1(1-CHLORO-6,6-DIMETHYL-2-HEPTEN-4-YNE)Related Search:

Terbinafine Hydrochloride 6,6-Dimethyl-1-hepten-4-yn-3-ol 1-CHLORO-6,6-DIMETHYL-2-HEPTENE-4-YNE 3,3-Dimethyl-1-butyne N-Methyl-2-naphthaMide

1-Methyl-aminomethyl naphthalene (Z)-N,6,6-triMethyl-N-(naphthalen-1-ylMethyl)hept-2-en-4-yn-1-aMine 1-Chloro-6,6-dimethyl-2-heptene-4-yne (E)-N,6,6-triMethyl-N-(naphthalen-2-ylMethyl)hept-2-en-4-yn-1-aMine Terbinafine

methyl-(naphthalen-2-ylmethyl)azanium N-[(2E)-6,6-DiMethyl-2-hepten-4-yn-1-yl]-N-Methyl-2-naphthaleneMethanaMine Hydrochloride cis-Terbinafine Hydrochloride (E)-1-Bromo-6,6-dimethyl-2-hepten-4-yne Chlorotrimethylsilane

chlorempenthrin

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2-HEPTEN-4-YNE, 1-CHLORO-6,6-DIMETHYL-, (2E)- 1-CHLORO-6,6-DIMETHYL-2-ENE-4-YNE-HEPTANE 1-Chloro-6,6-dimethyl-2-hepten-4-ino 2-HEPTEN-4-YNE,1-CHLORO-6,6-DIMETHYL 1-Chloro-6,6-dimethyl-2-hepten-4-yne (E)-1-chloro-6,6-diMethylhept-2-en-4-yne (2E)-1-chloro-6,6-dimethylhept-2-en-4-yne Terbinafine Impurity 22 Terbinafine Impurity 45 287471-30-1 Chemical intermediate for Terbinafine