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3-Acetamido-5-methylpyrazole

3-Acetamido-5-methylpyrazole structure

CAS No.: 83725-05-7

Chemical Name:: 3-Acetamido-5-methylpyrazole

Synonyms: N-(5-Methyl-1H-pyrazol-3-yl);3-Acetamido-5-methylpyrazole;N-(5-Methyl-2H-pyrazol-3-yl)acetamide;N-(5-methyl-1H-pyrazol-3-yl)acetamide;Acetamide, N-(5-methyl-1H-pyrazol-3-yl)-

CBNumber:: CB02105776

Molecular Formula:: C6H9N3O

Molecular Weight:: 139.16

MDL Number:

MOL File:: 83725-05-7.mol

MSDS File:: SDS

Last updated:2026-05-27 17:23:06

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3-Acetamido-5-methylpyrazole Properties

Boiling point	410.8±25.0 °C(Predicted)
Density	1.261
storage temp.	Sealed in dry,Room Temperature
pka	12.88±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09,GHS02
Signal word	Warning
Hazard statements	H332-H361-H373-H335-H336-H400-H411-H226
Precautionary statements	P501-P273-P260-P202-P240-P210-P233-P201-P243-P241-P242-P271-P280-P370+P378-P391-P308+P313-P303+P361+P353-P304+P340+P312-P403+P233-P403+P235-P405

3-Acetamido-5-methylpyrazole price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Activate Scientific	AS46305	N-(5-Methyl-1H-pyrazol-3-yl)acetamide 98%	83725-05-7	1g	$162	2026-06-04	Buy
Activate Scientific	AS46305	N-(5-Methyl-1H-pyrazol-3-yl)acetamide 98%	83725-05-7	5g	$524	2026-06-04	Buy
Matrix Scientific	298312	N-(5-Methyl-1H-pyrazol-3-yl)acetamide	83725-05-7	100.00mg	$30	2026-05-19	Buy
Matrix Scientific	298312	N-(5-Methyl-1H-pyrazol-3-yl)acetamide	83725-05-7	250.00mg	$43	2026-05-19	Buy
Matrix Scientific	298312	N-(5-Methyl-1H-pyrazol-3-yl)acetamide	83725-05-7	1.00g	$100	2026-05-19	Buy

Product number	Packaging	Price	Buy
AS46305	1g	$162	Buy
AS46305	5g	$524	Buy
298312	100.00mg	$30	Buy
298312	250.00mg	$43	Buy
298312	1.00g	$100	Buy

3-Acetamido-5-methylpyrazole Chemical Properties, Uses, Production

Synthesis

31230-17-8

108-24-7

83725-05-7

4.1.1 Synthesis of N-(5-methyl-1H-pyrazol-3-yl)-acetamide (2): 5-methyl-1H-pyrazol-3-amine (1) (10 g, 103 mmol) was dissolved in 100 mL of distilled water and sodium bicarbonate (NaHCO3) (26 g, 309 mmol) was added slowly. Subsequently, acetic anhydride (19.5 mL, 206 mmol) was added dropwise and the resulting suspension was heated and refluxed for 16 hours (the reaction process was monitored by thin layer chromatography (TLC)). Upon completion of the reaction, the mixture was cooled to room temperature and white crystals were observed to precipitate slowly. The precipitate was collected by filtration, washed with distilled water and dried to afford the target product N-(5-methyl-1H-pyrazol-3-yl)-acetamide (2) (6.2 g, 44 mmol, 43% yield), which did not require further purification. The melting point of the product was 210-211 °C; 1H NMR (400 MHz, DMSO-d6) δ 11.92 (s, 1H), 10.19 (s, 1H), 6.24 (s, 1H), 2.17 (s, 3H), 1.96 (s, 3H).

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 428 - 441

3-Acetamido-5-methylpyrazole synthesis

Synthesis of 3-Acetamido-5-methylpyrazole from 3-Amino-5-methylpyrazole and Acetic anhydride

3-Acetamido-5-methylpyrazole Preparation Products And Raw materials

Raw materials

3-Amino-5-methylpyrazole Acetic anhydride Sodium bicarbonate

Preparation Products

3-Acetamido-5-methylpyrazole Suppliers

Global Suppliers ( 45)

Supplier	Tel	Email	Country	ProdList	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Shanghai Synthfine Chemical Co.,Ltd	15921303235	sales@synthfine.com	China	995	58
Wuxi Zhangkun Biochemical Technology Co., Ltd.	+86 0510-85629785		China	2321	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Balmxy Pharmaceutical Co., Ltd	021-24206007 13764915196	sales@balmxy.com	China	6959	55
Shanghai ZhengXia Medical Technology Co., Ltd.	13585673075	317388297@qq.com	China	253	50
Chengdu Xiaojia Technology Co., Ltd.	15902830537	zhanghao@happysyn.com	China	2359	55
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Shanghai Pingguo Pharmaceutical Co., Ltd.	021-20432229	2412110556@qq.com	China	6016	55
Aikon International Limited	025-66113011 19370895928	qzhang@aikonchem.com	China	15390	58

Supplier	Advantage
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Shanghai Synthfine Chemical Co.,Ltd	58
Wuxi Zhangkun Biochemical Technology Co., Ltd.	58
Bide Pharmatech Ltd.	60
Shanghai Balmxy Pharmaceutical Co., Ltd	55
Shanghai ZhengXia Medical Technology Co., Ltd.	50
Chengdu Xiaojia Technology Co., Ltd.	55
Amadis Chemical Company Limited	58
Shanghai Pingguo Pharmaceutical Co., Ltd.	55
Aikon International Limited	58

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3-Acetamido-5-methylpyrazole N-(5-Methyl-1H-pyrazol-3-yl) N-(5-methyl-1H-pyrazol-3-yl)acetamide N-(5-Methyl-2H-pyrazol-3-yl)acetamide Acetamide, N-(5-methyl-1H-pyrazol-3-yl)- 83725-05-7