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3-Acetamido-5-methylpyrazole

CAS No.
83725-05-7
Chemical Name:
3-Acetamido-5-methylpyrazole
Synonyms
N-(5-Methyl-1H-pyrazol-3-yl);3-Acetamido-5-methylpyrazole;N-(5-Methyl-2H-pyrazol-3-yl)acetamide;N-(5-methyl-1H-pyrazol-3-yl)acetamide;Acetamide, N-(5-methyl-1H-pyrazol-3-yl)-
CBNumber:
CB02105776
Molecular Formula:
C6H9N3O
Molecular Weight:
139.16
MDL Number:
MOL File:
83725-05-7.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47
Product description Number Pack Size Price
N-(5-Methyl-1H-pyrazol-3-yl)acetamide W8674 1g $317
N-(5-METHYL-1H-PYRAZOL-3-YL)ACETAMIDE 95.00% CHM0393558 5MG $497.74
N-(5-Methyl-1H-pyrazol-3-yl)acetamide W8674 5g $851
N-(5-Methyl-1H-pyrazol-3-yl)acetamide W8674 10g $1596
N-(5-methyl-1H-pyrazol-3-yl)-Acetamide 97.00% P8015 5G $2180

3-Acetamido-5-methylpyrazole Properties

Boiling point 410.8±25.0 °C(Predicted)
Density 1.261
storage temp. Sealed in dry,Room Temperature
pka 12.88±0.10(Predicted)

3-Acetamido-5-methylpyrazole price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific W8674 N-(5-Methyl-1H-pyrazol-3-yl)acetamide 83725-05-7 1g $317 2021-12-16 Buy
American Custom Chemicals Corporation CHM0393558 N-(5-METHYL-1H-PYRAZOL-3-YL)ACETAMIDE 95.00% 83725-05-7 5MG $497.74 2021-12-16 Buy
AK Scientific W8674 N-(5-Methyl-1H-pyrazol-3-yl)acetamide 83725-05-7 5g $851 2021-12-16 Buy
AK Scientific W8674 N-(5-Methyl-1H-pyrazol-3-yl)acetamide 83725-05-7 10g $1596 2021-12-16 Buy
AccelPharmtech P8015 N-(5-methyl-1H-pyrazol-3-yl)-Acetamide 97.00% 83725-05-7 5G $2180 2021-12-16 Buy
Product number Packaging Price Buy
W8674 1g $317 Buy
CHM0393558 5MG $497.74 Buy
W8674 5g $851 Buy
W8674 10g $1596 Buy
P8015 5G $2180 Buy

3-Acetamido-5-methylpyrazole Chemical Properties,Uses,Production

Synthesis

3-Amino-5-methylpyrazole

31230-17-8

Acetic anhydride

108-24-7

3-Acetamido-5-methylpyrazole

83725-05-7

4.1.1 Synthesis of N-(5-methyl-1H-pyrazol-3-yl)-acetamide (2): 5-methyl-1H-pyrazol-3-amine (1) (10 g, 103 mmol) was dissolved in 100 mL of distilled water and sodium bicarbonate (NaHCO3) (26 g, 309 mmol) was added slowly. Subsequently, acetic anhydride (19.5 mL, 206 mmol) was added dropwise and the resulting suspension was heated and refluxed for 16 hours (the reaction process was monitored by thin layer chromatography (TLC)). Upon completion of the reaction, the mixture was cooled to room temperature and white crystals were observed to precipitate slowly. The precipitate was collected by filtration, washed with distilled water and dried to afford the target product N-(5-methyl-1H-pyrazol-3-yl)-acetamide (2) (6.2 g, 44 mmol, 43% yield), which did not require further purification. The melting point of the product was 210-211 °C; 1H NMR (400 MHz, DMSO-d6) δ 11.92 (s, 1H), 10.19 (s, 1H), 6.24 (s, 1H), 2.17 (s, 3H), 1.96 (s, 3H).

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 158, p. 428 - 441

31230-17-8
108-24-7
83725-05-7
Synthesis of 3-Acetamido-5-methylpyrazole from 3-Amino-5-methylpyrazole and Acetic anhydride

3-Acetamido-5-methylpyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

3-Acetamido-5-methylpyrazole Suppliers

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3-Acetamido-5-methylpyrazole N-(5-Methyl-1H-pyrazol-3-yl) N-(5-methyl-1H-pyrazol-3-yl)acetamide N-(5-Methyl-2H-pyrazol-3-yl)acetamide Acetamide, N-(5-methyl-1H-pyrazol-3-yl)- 83725-05-7