8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
- CAS No.
- 23583-48-4
- Chemical Name:
- 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
- Synonyms
- 8-BR-CAMP;8-BROMO-CAMP;B-cAMP;8-Br-A-3:5-MP;8-BR-CAMP,98+%;8-Bromocyclic AMP;Cyclic amp, 8-bromo;-CyclicMonophosphate;8-Bromo-cyclic 3',5'-amp;8-bromo-3',5'-cyclic AMP
- CBNumber:
- CB0218315
- Molecular Formula:
- C10H11BrN5O6P
- Molecular Weight:
- 408.1
- MDL Number:
- MFCD00075580
- MOL File:
- 23583-48-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 8-Bromoadenosine 3′,5′-cyclic monophosphate ≥97% (HPLC) | B5386 | 5mg | $46.4 |
| 8-Bromoadenosine 3′,5′-cyclic monophosphate ≥97% (HPLC) | B5386 | 25mg | $156 |
| 8-bromo Cyclic AMP ≥95% | 18141 | 10mg | $62 |
| 8-bromo Cyclic AMP ≥95% | 18141 | 25mg | $123 |
| 8-bromo Cyclic AMP ≥95% | 18141 | 50mg | $197 |
| More product size | |||
| Melting point | 254 °C (dec.) (lit.) |
|---|---|
| Boiling point | 741.9±70.0 °C(Predicted) |
| Density | 2.80±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | aqueous base: soluble |
| pka | 0.95±0.60(Predicted) |
| form | Powder |
| color | Pale Brown |
| Sensitive | Hygroscopic |
| BRN | 591930 |
| InChI | 1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | DVKQVRZMKBDMDH-UUOKFMHZSA-N |
| SMILES | Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Br)nc12 |
| FDA UNII | 5QO1UW05Q5 |
| UNSPSC Code | 41106305 |
| NACRES | NA.77 |
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B5386 | 8-Bromoadenosine 3′,5′-cyclic monophosphate ≥97% (HPLC) | 23583-48-4 | 5mg | $46.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | B5386 | 8-Bromoadenosine 3′,5′-cyclic monophosphate ≥97% (HPLC) | 23583-48-4 | 25mg | $156 | 2026-04-30 | Buy |
| Cayman Chemical | 18141 | 8-bromo Cyclic AMP ≥95% | 23583-48-4 | 10mg | $62 | 2026-04-30 | Buy |
| Cayman Chemical | 18141 | 8-bromo Cyclic AMP ≥95% | 23583-48-4 | 25mg | $123 | 2026-04-30 | Buy |
| Cayman Chemical | 18141 | 8-bromo Cyclic AMP ≥95% | 23583-48-4 | 50mg | $197 | 2026-04-30 | Buy |
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
8-Bromoadenosine 3′,5′-cyclic monophosphate has been used:
- to treat H295R cells as positive controls for CYP19 induction
- as a membrane permeable cAMP analog to study its effect on short-circuit current (Isc)
- to investigate its potential as an inducer of differentiation in Wharton′s jelly-derived mesenchymal stem cells (WJ-MSCs)
Definition
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase.
Biochem/physiol Actions
8-bromo-adenosine3′,5′-cyclicmonophosphate(8-bromo-cAMP), added to hepatocytes during plating helps to increase the acquisition of beta-adrenoceptors.
in vivo
8-Bromo-cAMP (60 mg/kg/day, i.p., 7 days) reduces tumor in CT26 tumor mice[4].
| Animal Model: | CT26 tumor mice[4] |
| Dosage: | 60 mg/kg/day |
| Administration: | i.p., 7 days |
| Result: | Decreases amounts of primary CRC tumor nodules and liver metastases. Reduces vasculogenic mimicry (PAS–CD31 staining of colorectal and intestinal tumors). Inhibits cAMP and VEGF expression, increases expression of PKA in tumor tissues. |
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20582 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9985 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89686 | 60 |
View Lastest Price from 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | 8-Bromo-cAMP
23583-48-4
|
$56.00-151.00 | 97.30% | 10g | TargetMol Chemicals Inc. | ||
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2020-03-05 | 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
23583-48-4
|
$1.00 | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-

- 8-Bromo-cAMP
23583-48-4
- $56.00-151.00
- 97.30%
- TargetMol Chemicals Inc.
-

- 8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
23583-48-4
- $1.00
- 98% HPLC
- Career Henan Chemical Co
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