ChemicalBook >> CAS DataBase List >>N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide structure

CAS No.: 26195-65-3

Chemical Name:: N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide

Synonyms: NSC 305987;Colchicine Impurity 25;N-Deacetyl-N-(trifluoroacetyl)colchicine;2,2,2-trifluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide;N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide;2,2,2-Trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetraMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide;Acetamide, 2,2,2-trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

CBNumber:: CB02255750

Molecular Formula:: C22H22F3NO6

Molecular Weight:: 453.41

MDL Number:

MOL File:: 26195-65-3.mol

Last updated:2023-05-15 10:44:00

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N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide Properties

Boiling point	681.3±55.0 °C(Predicted)
Density	1.36±0.1 g/cm3(Predicted)
solubility	soluble in Chloromethane, Dichlormethane, DMSO, Methanol
pka	9.68±0.40(Predicted)
form	Crystalline Powder
color	Faintly Yellow

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	T8416-26	N-Trifluoroacetyl Deacetylcolchicine	26195-65-3	50mg	$531	2026-06-04	Buy
TRC	T787025	N-TrifluoroacetylDeacetylcolchicine	26195-65-3	500mg	$1320	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0317318	N-TRIFLUOROACETYL DEACETYLCOLCHICINE 98.00%	26195-65-3	50MG	$716.1	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0317318	N-TRIFLUOROACETYL DEACETYLCOLCHICINE 98.00%	26195-65-3	500MG	$1686.3	2021-12-16	Buy

Product number	Packaging	Price	Buy
T8416-26	50mg	$531	Buy
T787025	500mg	$1320	Buy
HCH0317318	50MG	$716.1	Buy
HCH0317318	500MG	$1686.3	Buy

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide Chemical Properties, Uses, Production

Chemical Properties

Faintly Yellow Crystalline Powder

Uses

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide synthesis

Synthesis of N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide from (R/S)-N-Deacetyl Colchiceine

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide Preparation Products And Raw materials

Raw materials

trimethylcolchicinic acid methyl ether (R/S)-N-Deacetyl Colchiceine Trifluoroacetic anhydride

Preparation Products

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide Suppliers

Global Suppliers ( 12)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44927	58
Shanghai YuZn Pharm. Technology Co.,Ltd.	15921286451; 15921286451	2010681527@qq.com	China	4919	58
Shureli Biopharma Co.,Ltd	0871-68355600 18787766125	756338076@qq.com	China	676	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Energy Chemical	58
Shanghai YuZn Pharm. Technology Co.,Ltd.	58
Shureli Biopharma Co.,Ltd	58

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide 2,2,2-Trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetraMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide N-Deacetyl-N-(trifluoroacetyl)colchicine NSC 305987 2,2,2-trifluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide Acetamide, 2,2,2-trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]- Colchicine Impurity 25 26195-65-3