16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
- CAS No.
- 465-18-9
- Chemical Name:
- 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
- Synonyms
- Polyporenic acid C;Polyporenic acid C, 95%min;Polyporenic acid C, 10 mM in DMSO;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-dien-21-oic acid;3-Oxo-16α-hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid;16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid;cell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C;Lanosta-7,9(11)-dien-21-oic acid, 16-hydroxy-24-methylene-3-oxo-, (16α)-;16alpha-Hydroxy-24-methylene-3-oxo-5alpha-lanosta-7,9(11)-diene-30-oic acid;(2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
- CBNumber:
- CB02274704
- Molecular Formula:
- C31H46O4
- Molecular Weight:
- 482.7
- MDL Number:
- MFCD29904546
- MOL File:
- 465-18-9.mol
- MSDS File:
- SDS
| Melting point | 265-266℃ |
|---|---|
| Boiling point | 620.3±55.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 4.63±0.10(Predicted) |
| color | White to off-white |
| InChIKey | OWVUHYZGACFYHI-SUIRJFICNA-N |
| SMILES | C1(=O)C([C@@]2([H])[C@](C)(CC1)C1C([C@]3([C@@](CC=1)(C)[C@@H]([C@H](C)CCC(=C)C(C)C)[C@H](O)C3)C(O)=O)=CC2)(C)C |&1:3,5,11,12,16,17,26,r| |
| CAS DataBase Reference | 465-18-9 |
| FDA UNII | 8EC05EK77F |
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 44639 | Polyporenic Acid C ≥98% | 465-18-9 | 5mg | $235 | 2026-04-30 | Buy |
| Cayman Chemical | 44639 | Polyporenic Acid C ≥98% | 465-18-9 | 10mg | $400 | 2026-04-30 | Buy |
| Cayman Chemical | 44639 | Polyporenic Acid C ≥98% | 465-18-9 | 25mg | $705 | 2026-04-30 | Buy |
| Cayman Chemical | 44639 | Polyporenic Acid C ≥98% | 465-18-9 | 50mg | $1058 | 2026-04-30 | Buy |
| Usbiological | 300817 | Polyporenic acid C ≥98% | 465-18-9 | 5mg | $623 | 2026-06-03 | Buy |
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Poria cocos.
Uses
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].
Biological Activity
Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. It induces apoptosis through the death receptor-mediated apoptotic pathway without the involvement of mitochondria. It has the potential to be used in lung cancer research.
target
PARP | Caspase | PI3K | Akt | p53
References
[1] Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog.2009 Jun;48(6):498-507. DOI:10.1002/mc.20487
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5037 | 58 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9883 | 50 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
View Lastest Price from 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Polyporenic acid C
465-18-9
|
1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | ||
 |
2023-02-24 | Polyporenic acid C
465-18-9
|
5mg | ≥95%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | ||
 |
2020-01-13 | 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
465-18-9
|
$5.50 | 1KG | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
- Polyporenic acid C
465-18-9
- $0.00
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Polyporenic acid C
465-18-9
- $0.00
- ≥95%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
465-18-9
- $5.50
- 98%min
- Career Henan Chemical Co
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