3-FLUORO-5-HYDROXYBENZENEBORONIC ACID
- CAS No.
- 871329-82-7
- Chemical Name:
- 3-FLUORO-5-HYDROXYBENZENEBORONIC ACID
- Synonyms
- 3-Borono-5-fluorophenol;(3-Fluoro-5-hydroxyphenyl);3-Fluoro-5-hydroxybenzeneboronic;3-FLUORO-5-HYDROXYPHENYLBORONIC ACID;3-FLUORO-5-HYDROXYBENZENEBORONIC ACID;B-(3-Fluoro-5-hydroxyphenyl)boronic acid;Boronic acid, B-(3-fluoro-5-hydroxyphenyl)-;3-Fluoro-5-hydroxyphenylboronic Acid (contains varying amounts of Anhydride);3-Fluoro-5-hydroxybenzeneboronic Acid (contains varying amounts of Anhydride)
- CBNumber:
- CB0235875
- Molecular Formula:
- C6H6BFO3
- Molecular Weight:
- 155.92
- MDL Number:
- MFCD07363778
- MOL File:
- 871329-82-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-fluoro-5-hydroxybenzeneboronic acid AldrichCPR | CDS007717 | 250MG | $197 |
| 3-Fluoro-5-hydroxyphenylboronic Acid (contains varying amounts of Anhydride) | F0954 | 1g | $123 |
| 3-Fluoro-5-hydroxyphenylboronic acid 97-105%(Assaybytitration) | 40303 | 1G | $118.08 |
| 3-Fluoro-5-hydroxybenzeneboronic acid | 118401 | 10.00g | $649 |
| (3-Fluoro-5-hydroxyphenyl)boronic acid 98% | AA004KJI | 100mg | $10 |
| More product size | |||
| Melting point | 54-62 |
|---|---|
| Boiling point | 380.0±52.0 °C(Predicted) |
| Density | 1.42 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 7.23±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Slightly soluble in water. |
| InChI | InChI=1S/C6H6BFO3/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,9-11H |
| InChIKey | RMBFBZIEXCTPDB-UHFFFAOYSA-N |
| SMILES | B(C1=CC(O)=CC(F)=C1)(O)O |
| CAS DataBase Reference | 871329-82-7 |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2931900090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-FLUORO-5-HYDROXYBENZENEBORONIC ACID price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS007717 | 3-fluoro-5-hydroxybenzeneboronic acid AldrichCPR | 871329-82-7 | 250MG | $197 | 2026-04-30 | Buy |
| TCI Chemical | F0954 | 3-Fluoro-5-hydroxyphenylboronic Acid (contains varying amounts of Anhydride) | 871329-82-7 | 1g | $123 | 2026-04-30 | Buy |
| Chem-Impex | 40303 | 3-Fluoro-5-hydroxyphenylboronic acid 97-105%(Assaybytitration) | 871329-82-7 | 1G | $118.08 | 2026-05-19 | Buy |
| Matrix Scientific | 118401 | 3-Fluoro-5-hydroxybenzeneboronic acid | 871329-82-7 | 10.00g | $649 | 2026-05-18 | Buy |
| aablocks | AA004KJI | (3-Fluoro-5-hydroxyphenyl)boronic acid 98% | 871329-82-7 | 100mg | $10 | 2026-05-28 | Buy |
3-FLUORO-5-HYDROXYBENZENEBORONIC ACID Chemical Properties,Uses,Production
Uses
suzuki reaction
Uses
3-Fluoro-5-hydroxybenzeneboronic acid is used as pharmaceutical intermediate.
Synthesis
609807-25-2
871329-82-7
Under nitrogen protection, (3-fluoro-5-methoxyphenyl)boronic acid (500 mg, 2.942 mmol) was dissolved in dichloromethane (15 mL) and cooled to 0°C. A dichloromethane solution of 1 M boron tribromide (14.7 mL, 14.7 mmol) was slowly added dropwise. The reaction mixture was stirred at room temperature for 3 h. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was concentrated under reduced pressure. Water (15 mL) was added to the residue and the pH was adjusted to 2 with 1 M aqueous hydrochloric acid. the product was extracted with ethyl acetate (2 x 25 mL). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give (3-fluoro-5-hydroxyphenyl)boronic acid (430 mg) as an off-white solid.
References
[1] Patent: WO2015/58084, 2015, A1. Location in patent: Paragraph 0222
3-FLUORO-5-HYDROXYBENZENEBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from 3-FLUORO-5-HYDROXYBENZENEBORONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-06 | 3-FLUORO-5-HYDROXYBENZENEBORONIC ACID
871329-82-7
|
$1.00 | 1KG | 97%-99% | 1kg; 5kg; 100kg | Career Henan Chemical Co |
-
- 3-FLUORO-5-HYDROXYBENZENEBORONIC ACID
871329-82-7
- $1.00
- 97%-99%
- Career Henan Chemical Co
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