ChemicalBook >> CAS DataBase List >>1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE

CAS No.
51843-24-4
Chemical Name:
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
Synonyms
1-(5-chloro-1H-indol-3-yl)ethan-1-one;3-ACETYL-5-CHLOROINDOLE;5-chloro-3-acetyl-indole;5-chloro-3-indolyl -ethanone;1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE;1-(5-chloro-1H-indole-3-yl)ethylone;Ethanone, 1-(5-chloro-1H-indol-3-yl)-
CBNumber:
CB0236074
Molecular Formula:
C10H8ClNO
Molecular Weight:
193.63
MDL Number:
MFCD07437837
MOL File:
51843-24-4.mol
MSDS File:
SDS
Last updated:2026-05-27 17:23:46
Product description Number Pack Size Price
1-(5-Chloro-1H-indol-3-yl)ethanone 95% OR913238 250mg $73
1-(5-Chloro-1H-indol-3-yl)ethanone 95% OR913238 1g $115
1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) W6667 250mg $43
1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) W6667 1g $139
1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) W6667 5g $460

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Properties

Melting point 168 °C (decomp)(Solv: ethyl ether (60-29-7))
Boiling point 367.9±22.0 °C(Predicted)
Density 1.332
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 14.46±0.30(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR913238 1-(5-Chloro-1H-indol-3-yl)ethanone 95% 51843-24-4 250mg $73 2026-06-04 Buy
Apolloscientific OR913238 1-(5-Chloro-1H-indol-3-yl)ethanone 95% 51843-24-4 1g $115 2026-06-04 Buy
AK Scientific W6667 1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) 51843-24-4 250mg $43 2026-06-04 Buy
AK Scientific W6667 1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) 51843-24-4 1g $139 2026-06-04 Buy
AK Scientific W6667 1-(5-Chloro-1H-indol-3-yl)ethanone 98%(HPLC) 51843-24-4 5g $460 2026-06-04 Buy
Product number Packaging Price Buy
OR913238 250mg $73 Buy
OR913238 1g $115 Buy
W6667 250mg $43 Buy
W6667 1g $139 Buy
W6667 5g $460 Buy

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Chemical Properties,Uses,Production

Synthesis

5-Chloroindole

17422-32-1

Acetic anhydride

108-24-7

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE

51843-24-4

The general procedure for the synthesis of 5-chloro-3-indoleacetophenone from 5-chloroindole and ethanoic anhydride: 1 mmol of 5-chloroindole, 1 mmol of ethanoic anhydride, 0.01 mmol of metal salt catalyst of trifluoromethanesulfonic acid, and 1 mmol of ionic liquid were sequentially added to a 10 mL glass reaction tube suitable for single mode microwave reaction. Subsequently, the reaction tube was sealed with a polytetrafluoroethylene cap and placed in a single-mode microwave reactor, and the microwave radiation reaction was carried out under different temperature and time conditions to optimize the reaction conditions. After completion of the reaction, the reaction tube was cooled to room temperature and the reaction mixture was extracted with ether (5 × 10 mL). The ether layer was separated and washed with deionized water (2 × 10 mL), saturated aqueous sodium bicarbonate solution (2 × 20 mL) and saturated saline (2 × 10 mL) sequentially. The organic phase was dried over anhydrous magnesium sulfate and filtered, and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography (silica gel, n-hexane/ethyl acetate, gradient elution ratio from 10:0 to 8:2) to obtain the target product 5-chloro-3-indoleacetophenone, and the isolated yield was calculated.

References

[1] RSC Advances, 2017, vol. 7, # 86, p. 54399 - 54406
[2] Molecules, 2015, vol. 20, # 10, p. 19605 - 19619
[3] Journal of Medicinal Chemistry, 2002, vol. 45, # 15, p. 3184 - 3194
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 7, p. 3149 - 3157
[5] Journal of Heterocyclic Chemistry, 2007, vol. 44, # 4, p. 793 - 801

17422-32-1
75-36-5
51843-24-4
Synthesis of 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE from 5-Chloroindole and Acetyl chloride

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Suppliers

Global( 71)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
+86-0371-86658258 factory@coreychem.com China 29780 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 17705817739 info@dycnchem.com China 52693 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49859 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +86-15965530500 nickzhang@hangyubiotech.com China 9932 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501 product@acmec-e.com China 33301 58
Aladdin Scientific
tp@aladdinsci.com United States 54746 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131885 58
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9973 58

View Lastest Price from 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE pictures 2020-01-10 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
51843-24-4
1KG 98%; 99% 500g;1kg; 25kg Career Henan Chemical Co
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE 3-ACETYL-5-CHLOROINDOLE 5-chloro-3-acetyl-indole 5-chloro-3-indolyl -ethanone Ethanone, 1-(5-chloro-1H-indol-3-yl)- 1-(5-chloro-1H-indole-3-yl)ethylone 1-(5-chloro-1H-indol-3-yl)ethan-1-one 51843-24-4 Indole