1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
- CAS No.
- 51843-24-4
- Chemical Name:
- 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
- Synonyms
- 3-ACETYL-5-CHLOROINDOLE;5-chloro-3-acetyl-indole;5-chloro-3-indolyl -ethanone;1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE;Ethanone, 1-(5-chloro-1H-indol-3-yl)-;1-(5-chloro-1H-indol-3-yl)ethan-1-one
- CBNumber:
- CB0236074
- Molecular Formula:
- C10H8ClNO
- Molecular Weight:
- 193.63
- MDL Number:
- MFCD07437837
- MOL File:
- 51843-24-4.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C368950 | 1-(5-Chloro-1H-indol-3-yl)ethanone | 51843-24-4 | 500mg | $110 | 2021-12-16 | Buy |
| TRC | C368950 | 1-(5-Chloro-1H-indol-3-yl)ethanone | 51843-24-4 | 100mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC32873 | 1-(5-Chloro-1H-indol-3-yl)ethanone | 51843-24-4 | 100mg | $74 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC32873 | 1-(5-Chloro-1H-indol-3-yl)ethanone | 51843-24-4 | 500mg | $185 | 2021-12-16 | Buy |
| Apolloscientific | OR913238 | 1-(5-Chloro-1H-indol-3-yl)ethanone 95% | 51843-24-4 | 250mg | $247 | 2021-12-16 | Buy |
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Chemical Properties,Uses,Production
Synthesis
17422-32-1
108-24-7
51843-24-4
The general procedure for the synthesis of 5-chloro-3-indoleacetophenone from 5-chloroindole and ethanoic anhydride: 1 mmol of 5-chloroindole, 1 mmol of ethanoic anhydride, 0.01 mmol of metal salt catalyst of trifluoromethanesulfonic acid, and 1 mmol of ionic liquid were sequentially added to a 10 mL glass reaction tube suitable for single mode microwave reaction. Subsequently, the reaction tube was sealed with a polytetrafluoroethylene cap and placed in a single-mode microwave reactor, and the microwave radiation reaction was carried out under different temperature and time conditions to optimize the reaction conditions. After completion of the reaction, the reaction tube was cooled to room temperature and the reaction mixture was extracted with ether (5 × 10 mL). The ether layer was separated and washed with deionized water (2 × 10 mL), saturated aqueous sodium bicarbonate solution (2 × 20 mL) and saturated saline (2 × 10 mL) sequentially. The organic phase was dried over anhydrous magnesium sulfate and filtered, and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography (silica gel, n-hexane/ethyl acetate, gradient elution ratio from 10:0 to 8:2) to obtain the target product 5-chloro-3-indoleacetophenone, and the isolated yield was calculated.
References
[1] RSC Advances, 2017, vol. 7, # 86, p. 54399 - 54406
[2] Molecules, 2015, vol. 20, # 10, p. 19605 - 19619
[3] Journal of Medicinal Chemistry, 2002, vol. 45, # 15, p. 3184 - 3194
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 7, p. 3149 - 3157
[5] Journal of Heterocyclic Chemistry, 2007, vol. 44, # 4, p. 793 - 801
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Preparation Products And Raw materials
1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49983 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | sales@capotchem.com | China | 18207 | 66 |
View Lastest Price from 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
51843-24-4
|
US $0.01 / KG | 1KG | 98%; 99% | 500g;1kg； 25kg | Career Henan Chemical Co |
-
- 1-(5-CHLORO-1H-INDOL-3-YL)ETHANONE
51843-24-4
- US $0.01 / KG
- 98%; 99%
- Career Henan Chemical Co
