Dimethyl hydroxymethylphosphonate
- CAS No.
- 24630-67-9
- Chemical Name:
- Dimethyl hydroxymethylphosphonate
- Synonyms
- Dimethyl hydroxymethylphosphonate;Hydroxymethylphosphonic acid dimethyl ester;Phosphonic acid, P-(hydroxymethyl)-, dimethyl ester
- CBNumber:
- CB02462149
- Molecular Formula:
- C3H9O4P
- Molecular Weight:
- 140.07
- MDL Number:
- MFCD11053766
- MOL File:
- 24630-67-9.mol
- MSDS File:
- SDS
| Boiling point | 209℃ |
|---|---|
| Density | 1.245 |
| Flash point | 80℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 12.73±0.10(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C3H9O4P/c1-6-8(5,3-4)7-2/h4H,3H2,1-2H3 |
| InChIKey | OIERWUPLBOKSRB-UHFFFAOYSA-N |
| SMILES | P(CO)(=O)(OC)OC |
| CAS DataBase Reference | 24630-67-9(CAS DataBase Reference) |
Dimethyl hydroxymethylphosphonate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | ZAA63067 | Dimethyl (hydroxymethyl)phosphonate | 24630-67-9 | 1g | $1840.8 | 2026-06-05 | Buy |
| Biosynth | ZAA63067 | Dimethyl (hydroxymethyl)phosphonate | 24630-67-9 | 10g | $5900 | 2026-06-05 | Buy |
| ChemScene | CS-W006438 | Dimethyl (hydroxymethyl)phosphonate ≥91% | 24630-67-9 | 5g | $49 | 2026-06-04 | Buy |
| ChemScene | CS-W006438 | Dimethyl (hydroxymethyl)phosphonate ≥91% | 24630-67-9 | 10g | $75 | 2026-06-04 | Buy |
| ChemScene | CS-W006438 | Dimethyl (hydroxymethyl)phosphonate ≥91% | 24630-67-9 | 25g | $181 | 2026-06-04 | Buy |
Dimethyl hydroxymethylphosphonate Chemical Properties,Uses,Production
Synthesis
50-00-0
868-85-9
24630-67-9
Under stirring conditions, dimethyl phosphite (10.0 mL, 109 mmol), triethylamine (1.5 mL, 10.9 mmol) and paraformaldehyde (3.26 g) were mixed. The mixture was heated in an oil bath (external temperature) at 100°C. After 2.5 hours of reaction, the mixture was cooled to room temperature and subsequently concentrated under vacuum. The residue was purified by fast column chromatography (eluent: ethyl acetate/methanol, 95:5, v/v) to afford dimethyl hydroxymethylphosphonate as a colorless oil (9.41 g, 62% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 4.32 (1H, br s), 3.95 (2H, d, J = 6 Hz), 3.83 (3H, s), 3.81 (3H, s); 31P{1H} NMR (400.1 MHz, CDCl3): δ 27.8; 13C NMR (100.6 MHz. CDCl3): δ 53.5, 56.0, 57.6.
References
[1] Journal of Polymer Science, Part A: Polymer Chemistry, 2012, vol. 50, # 12, p. 2432 - 2443
[2] Chemistry - A European Journal, 2009, vol. 15, # 9, p. 2064 - 2070
[3] Patent: WO2006/20779, 2006, A2. Location in patent: Page/Page column 77
[4] Organic Letters, 2012, vol. 14, # 18, p. 4798 - 4801
[5] Bioorganic and Medicinal Chemistry, 1998, vol. 6, # 3, p. 315 - 322
Dimethyl hydroxymethylphosphonate Preparation Products And Raw materials
Dimethyl hydroxymethylphosphonate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Thoreco Novel Material Co. Ltd | 021-34202258 19391107643 | Sales@thoreco.com | China | 183 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| Shanghai Meishui Chemical Technology Co., Ltd | 021-60549325 18616193163 | China | 4518 | 56 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou Copiore Chemical Co., Ltd. | 17300981287 13757145729 | sales@copiore.com | China | 289 | 58 |
| Haimen Ruiyi Medical Tech Co., LTD | 021-54718086 | sales5@ruiyitech.com | China | 271 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Lastest Price from Dimethyl hydroxymethylphosphonate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Dimethyl (hydroxymethyl)phosphonate
24630-67-9
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-12-23 | Dimethyl(hydroxymethyl)phosphonate
24630-67-9
|
1kg | 98% | 100kg | XINXIANG RUNYU MATERIAL CO., LTD. | ||
 |
2021-08-12 | Dimethyl hydroxymethylphosphonate
24630-67-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Dimethyl (hydroxymethyl)phosphonate
24630-67-9
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Dimethyl(hydroxymethyl)phosphonate
24630-67-9
- 98%
- XINXIANG RUNYU MATERIAL CO., LTD.
-
- Dimethyl hydroxymethylphosphonate
24630-67-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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