ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE
- CAS No.
- 481054-89-1
- Chemical Name:
- ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE
- Synonyms
- ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE;6-BroMoquinoline-3-carboxylic acid ethyl ester;3-Quinolinecarboxylic acid, 6-bromo-, ethyl ester
- CBNumber:
- CB02465054
- Molecular Formula:
- C12H10BrNO2
- Molecular Weight:
- 280.12
- MDL Number:
- MFCD11877875
- MOL File:
- 481054-89-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 6-bromoquinoline-3-carboxylate 95% | AA00DKTO | 100mg | $12 |
| Ethyl 6-bromoquinoline-3-carboxylate 95% | AA00DKTO | 250mg | $14 |
| Ethyl 6-bromoquinoline-3-carboxylate 96% | AA00DKTO | 1g | $36 |
| Ethyl 6-bromoquinoline-3-carboxylate 96% | AA00DKTO | 5g | $171 |
| Ethyl 6-bromoquinoline-3-carboxylate 97% | W158822 | 5G | $225 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P501-P260-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405 |
ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00DKTO | Ethyl 6-bromoquinoline-3-carboxylate 95% | 481054-89-1 | 100mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00DKTO | Ethyl 6-bromoquinoline-3-carboxylate 95% | 481054-89-1 | 250mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00DKTO | Ethyl 6-bromoquinoline-3-carboxylate 96% | 481054-89-1 | 1g | $36 | 2026-05-28 | Buy |
| aablocks | AA00DKTO | Ethyl 6-bromoquinoline-3-carboxylate 96% | 481054-89-1 | 5g | $171 | 2026-05-28 | Buy |
| ACHEMBLOCK | W158822 | Ethyl 6-bromoquinoline-3-carboxylate 97% | 481054-89-1 | 5G | $225 | 2026-05-27 | Buy |
ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
10601-80-6
20357-20-4
481054-89-1
Step 1: Synthesis of ethyl 6-bromoquinoline-3-carboxylate To a solution of 5-bromo-2-nitrobenzaldehyde (2 g, 9 mmol) in ethanol (46 mL) was sequentially added tin(II) chloride dihydrate (7.95 g, 35.2 mmol) and ethyl 3,3-diethoxypropionate (4.2 mL, 22 mmol). The reaction mixture was heated to 90 °C and maintained for 16 hours. Upon completion of the reaction, it was cooled to room temperature and stirring was continued overnight. Subsequently, the reaction mixture was concentrated and the residue was dissolved in ethyl acetate. The solution was poured into a saturated aqueous sodium bicarbonate solution to form an emulsion. The emulsion was filtered through diatomaceous earth and the diatomaceous earth was rinsed with ethyl acetate. The organic and aqueous layers were separated and the aqueous phase was further extracted with ethyl acetate. All organic phases were combined, washed with brine, dried over magnesium sulfate, filtered and concentrated. Finally, purification by fast column chromatography (eluent: 0-50% ethyl acetate/heptane gradient) gave ethyl 6-bromoquinoline-3-carboxylate (1.41 g, 60% yield) as a solid.
References
[1] Journal of Organic Chemistry, 2010, vol. 75, # 10, p. 3488 - 3491
[2] Patent: US2012/270893, 2012, A1. Location in patent: Page/Page column 32
ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 6-BROMOQUINOLINE-3-CARBOXYLATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49892 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
