ChemicalBook >> CAS DataBase List >>8-Methyl-2,4-dichloroquinazoline

8-Methyl-2,4-dichloroquinazoline

CAS No.
39576-83-5
Chemical Name:
8-Methyl-2,4-dichloroquinazoline
Synonyms
2,4-DICHLORO-8-METHYLQUINAZOLINE;8-Methyl-2,4-dichloroquinazoline;Quinazoline, 2,4-dichloro-8-methyl-
CBNumber:
CB02465650
Molecular Formula:
C9H6Cl2N2
Molecular Weight:
213.06
MDL Number:
MFCD11849266
MOL File:
39576-83-5.mol
Last updated:2026-09-12 18:48:00

8-Methyl-2,4-dichloroquinazoline Properties

Boiling point 292℃
Density 1.418
Flash point 158℃
storage temp. Inert atmosphere,Room Temperature
pka -0.20±0.30(Predicted)
Appearance White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

8-Methyl-2,4-dichloroquinazoline price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth PBA57683 2,4-Dichloro-8-methylquinazoline 39576-83-5 1g $324.5 2026-06-04 Buy
Biosynth PBA57683 2,4-Dichloro-8-methylquinazoline 39576-83-5 2g $389.4 2026-06-04 Buy
Biosynth PBA57683 2,4-Dichloro-8-methylquinazoline 39576-83-5 5g $778.8 2026-06-04 Buy
Biosynth PBA57683 2,4-Dichloro-8-methylquinazoline 39576-83-5 10g $1103.3 2026-06-04 Buy
Matrix Scientific 118759 2,4-Dichloro-8-methylquinazoline 39576-83-5 500.00mg $429 2026-05-18 Buy
Product number Packaging Price Buy
PBA57683 1g $324.5 Buy
PBA57683 2g $389.4 Buy
PBA57683 5g $778.8 Buy
PBA57683 10g $1103.3 Buy
118759 500.00mg $429 Buy

8-Methyl-2,4-dichloroquinazoline Chemical Properties, Uses, Production

Synthesis

8-methylquinazoline-2,4(1H,3H)-dione

67449-23-4

8-METHYL-2,4-DICHLOROQUINAZOLINE

39576-83-5

The general procedure for the synthesis of 2,4-dichloro-8-methylquinazoline from 2,4-dihydroxy-8-methylquinazoline was as follows: 8-methylquinazoline-2,4(1H,3H)-dione (4.50 g, 25.50 mmol) was added to phosphorochloridic acid (47.6 mL, 510.9 mmol). The reaction mixture was stirred at 100 °C for 6 h and subsequently cooled to room temperature. The reaction solution was slowly poured into water (300 mL) and the internal temperature was controlled to be below 60°C. After precipitating the solid, the product was collected by filtration to afford 2,4-dichloro-8-methylquinazoline (4.30 g, 79% yield).

References

[1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 254 - 259
[2] Patent: US5064833, 1991, A
[3] Patent: EP322133, 1991, B1
[4] Patent: EP322133, 1989, A1
[5] Synthesis (Germany), 2016, vol. 48, # 8, p. 1226 - 1234

8-Methyl-2,4-dichloroquinazoline Preparation Products And Raw materials

8-Methyl-2,4-dichloroquinazoline Suppliers

Global Suppliers ( 63)
Supplier Tel Email Country ProdList Advantage
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3996 55
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2277 58
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
Nantong Bosu Pharmaceutical Technology Co., Ltd. 0513-51005092; 15962844273 tashiyxy@163.com China 914 58
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55

View Latest Price from 8-Methyl-2,4-dichloroquinazoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-dichloro-8-methylquinazoline pictures 2019-07-10 2,4-dichloro-8-methylquinazoline
39576-83-5
$8.80 1KG 97%-99% 100kg Career Henan Chemical Co

8-Methyl-2,4-dichloroquinazoline Spectrum

Quinazoline, 2,4-dichloro-8-methyl- 2,4-DICHLORO-8-METHYLQUINAZOLINE 8-Methyl-2,4-dichloroquinazoline 39576-83-5 39576-82-6