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5-METHOXYQUINOLIN-2(1H)-ONE

5-METHOXYQUINOLIN-2(1H)-ONE Structure
5-METHOXYQUINOLIN-2(1H)-ONE structure
CAS No.
160893-04-9
Chemical Name:
5-METHOXYQUINOLIN-2(1H)-ONE
Synonyms
5-methoxyquinolin-2-ol;5-METHOXYQUINOLIN-2(1H)-ONE;2(1H)-Quinolinone, 5-methoxy-;5-Methoxyquinolin-2(1H)-one 95+%
CBNumber:
CB02468282
Molecular Formula:
C10H9NO2
Molecular Weight:
175.18
MDL Number:
MFCD11877926
MOL File:
160893-04-9.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46
Product description Number Pack Size Price
5-Methoxyquinolin-2(1H)-one 8128AA 100mg $259
5-Methoxyquinolin-2(1H)-one 4H56-1-0R8 250mg $375
5-METHOXYQUINOLIN-2(1H)-ONE 95.00% CHM0390866 5MG $496.58
5-Methoxyquinolin-2(1H)-one 4H56-1-0R8 1g $936
5-Methoxyquinolin-2(1H)-one 8128AA 5g $2413
Request For Quotation

5-METHOXYQUINOLIN-2(1H)-ONE Properties

storage temp. Inert atmosphere,Room Temperature
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933499090

5-METHOXYQUINOLIN-2(1H)-ONE price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 8128AA 5-Methoxyquinolin-2(1H)-one 160893-04-9 100mg $259 2021-12-16 Buy
SynQuest Laboratories 4H56-1-0R8 5-Methoxyquinolin-2(1H)-one 160893-04-9 250mg $375 2021-12-16 Buy
American Custom Chemicals Corporation CHM0390866 5-METHOXYQUINOLIN-2(1H)-ONE 95.00% 160893-04-9 5MG $496.58 2021-12-16 Buy
SynQuest Laboratories 4H56-1-0R8 5-Methoxyquinolin-2(1H)-one 160893-04-9 1g $936 2021-12-16 Buy
AK Scientific 8128AA 5-Methoxyquinolin-2(1H)-one 160893-04-9 5g $2413 2021-12-16 Buy
Product number Packaging Price Buy
8128AA 100mg $259 Buy
4H56-1-0R8 250mg $375 Buy
CHM0390866 5MG $496.58 Buy
4H56-1-0R8 1g $936 Buy
8128AA 5g $2413 Buy

5-METHOXYQUINOLIN-2(1H)-ONE Chemical Properties,Uses,Production

Synthesis

5-methoxyquinoline 1-oxide

90924-16-6

5-METHOXYQUINOLIN-2(1H)-ONE

160893-04-9

4.4 At room temperature, 5-methoxyquinoline azide (Compound 2, 4.09 g, 23.3 mmol) was dissolved in a solvent mixture of 10% aqueous K2CO3 (60 mL) and dichloromethane (60 mL). Subsequently, p-toluenesulfonyl chloride (5.55 g, 29.1 mmol) was added in batches and the reaction mixture was stirred at the same temperature for 18 hours. Upon completion of the reaction, ether was added to precipitate the product, and the precipitate was collected by filtration and washed with ether. The resulting solid was dried in an oven at 65 °C for 2 h to give 5-methoxyquinolin-2(1H)-one as a pale yellow solid, yield: 2.651 g (65%). The product was characterized by 1H NMR (400 MHz, CDCl3) and 13C NMR (100 MHz, CDCl3) with the following data: 1H NMR δ 12.15 (br.s, 1H), 8.25 (d, J = 9.6 Hz, 1H), 7.45 (t, J = 8.4 Hz, 1H), 7.04 (d, J = 8.4 Hz, 1H) 6.67 (t, J = 9.2 Hz, 2H), 3.97 (s, 3H); 13C NMR δ 164.61, 156.09, 139.72, 135.74, 131.40, 119.67, 110.91, 108.66, 102.78, 55.73.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 754 - 768
[2] Patent: KR101778938, 2017, B1. Location in patent: Paragraph 0147-0148; 0155; 0175-0177

5-METHOXYQUINOLIN-2(1H)-ONE Preparation Products And Raw materials

Raw materials

5-methoxyquinoline 1-oxide N-(2-FORMYL-3-METHOXY-PHENYL)-2,2-DIMETHYL-PROPIONAMIDE Tosyl chloride Potassium carbonate Dichloromethane
Water

1of2

Preparation Products

5-METHOXYQUINOLIN-2(1H)-ONE Suppliers

Global( 31)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Zhengzhou Lingzhiyue Technology Co., Ltd 		+86-0371-55074660 +8613523716970 Lingzhiyue@aliyun.com China 3145 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 7999 62
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22345 58
3A Chemicals 400-668-9898 service@3achem.com China 20557 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 52684 58
Chengdu Forest Science and Technology Development Co,. Ltd 028-87925786 18010564218 vendi@cdforestchem.com China 1992 58
Jiangsu aikang biomedical research and development co., LTD 025-58859352 13155353615 qzhang@aikonchem.com China 15525 58
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Zhengzhou Lingzhiyue Technology Co., Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Amadis Chemical Company Limited 		58
ShangHai Biochempartner Co.,Ltd 62
Wuxi AppTec 58
3A Chemicals 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 58
Chengdu Forest Science and Technology Development Co,. Ltd 58
Jiangsu aikang biomedical research and development co., LTD 58

5-METHOXYQUINOLIN-2(1H)-ONE Spectrum

5-METHOXYQUINOLIN-2(1H)-ONE(160893-04-9)1HNMR
5-METHOXYQUINOLIN-2(1H)-ONE 5-Methoxyquinolin-2(1H)-one 95+% 2(1H)-Quinolinone, 5-methoxy- 5-methoxyquinolin-2-ol 160893-04-9