5-Methoxyquinolin-2(1H)-one
- CAS No.
- 160893-04-9
- Chemical Name:
- 5-Methoxyquinolin-2(1H)-one
- Synonyms
- 5-methoxyquinolin-2-ol;5-Methoxyquinolin-2(1H)-one;2(1H)-Quinolinone, 5-methoxy-;5-Methoxyquinolin-2(1H)-one 95+%
- CBNumber:
- CB02468282
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD11877926
- MOL File:
- 160893-04-9.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933499090 |
5-Methoxyquinolin-2(1H)-one price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR55141 | 5-Methoxyquinolin-2(1H)-one 97% | 160893-04-9 | 100mg | $37 | 2026-06-04 | Buy |
| Apolloscientific | OR55141 | 5-Methoxyquinolin-2(1H)-one 97% | 160893-04-9 | 250mg | $45 | 2026-06-04 | Buy |
| Apolloscientific | OR55141 | 5-Methoxyquinolin-2(1H)-one 97% | 160893-04-9 | 1g | $176 | 2026-06-04 | Buy |
| Matrix Scientific | 308356 | 5-Methoxyquinolin-2(1H)-one | 160893-04-9 | 100.00mg | $38 | 2026-05-19 | Buy |
| Matrix Scientific | 308356 | 5-Methoxyquinolin-2(1H)-one | 160893-04-9 | 250.00mg | $43 | 2026-05-19 | Buy |
5-Methoxyquinolin-2(1H)-one Chemical Properties, Uses, Production
Synthesis
90924-16-6
160893-04-9
4.4 At room temperature, 5-methoxyquinoline azide (Compound 2, 4.09 g, 23.3 mmol) was dissolved in a solvent mixture of 10% aqueous K2CO3 (60 mL) and dichloromethane (60 mL). Subsequently, p-toluenesulfonyl chloride (5.55 g, 29.1 mmol) was added in batches and the reaction mixture was stirred at the same temperature for 18 hours. Upon completion of the reaction, ether was added to precipitate the product, and the precipitate was collected by filtration and washed with ether. The resulting solid was dried in an oven at 65 °C for 2 h to give 5-methoxyquinolin-2(1H)-one as a pale yellow solid, yield: 2.651 g (65%). The product was characterized by 1H NMR (400 MHz, CDCl3) and 13C NMR (100 MHz, CDCl3) with the following data: 1H NMR δ 12.15 (br.s, 1H), 8.25 (d, J = 9.6 Hz, 1H), 7.45 (t, J = 8.4 Hz, 1H), 7.04 (d, J = 8.4 Hz, 1H) 6.67 (t, J = 9.2 Hz, 2H), 3.97 (s, 3H); 13C NMR δ 164.61, 156.09, 139.72, 135.74, 131.40, 119.67, 110.91, 108.66, 102.78, 55.73.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 754 - 768
[2] Patent: KR101778938, 2017, B1. Location in patent: Paragraph 0147-0148; 0155; 0175-0177
5-Methoxyquinolin-2(1H)-one Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
5-Methoxyquinolin-2(1H)-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Wuxi AppTec | 022-59987777 13552403979 | jia_guoqiang@wuxiapptec.com | China | 22344 | 58 |
| 3A Chemicals | 400-668-9898 | service@3achem.com | China | 20535 | 58 |
| Chengdu Forest Science and Technology Development Co,. Ltd | 028-87925786 18010564218 | vendi@cdforestchem.com | China | 1992 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| Wuhan chuanghao Biotechnology Co., Ltd | 13361917963 | 876725023@qq.com | China | 282 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 13393710386 | 3941078109@qq.com | China | 9844 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Henan Lavoisier Chemical Products Co. Ltd | 0371-63682289 18625781376 | sales@lavoisier.cn | China | 4999 | 58 |
