AM2201
- CAS No.
- 335161-24-5
- Chemical Name:
- AM2201
- Synonyms
- AM-2201;[1-(5-fluoropentyl)-1H-indole-3-yl](naphthalene-1-yl)methanone;AM2201 (CRM);AM-2201 (AM 2201;AM2201 (exempt preparation);AM-2201, 1mg/ml in Methanol;AM-2201, 0.1mg/ml in Methanol;AM-2201 (1.0 mg/ml in Methanol);1-(5-fluoropentyl)-3-(1-naphthoyl)indole;1-(5-fluoropentyl)-3-(naphtalen-1-oy)indole
- CBNumber:
- CB02485090
- Molecular Formula:
- C24H22FNO
- Molecular Weight:
- 359.44
- MDL Number:
- MFCD16620503
- MOL File:
- 335161-24-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 551.1±30.0 °C(Predicted) |
|---|---|
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | -10 to -25°C |
| solubility | DMSO: 2mg/mL, clear |
| form | powder |
| color | white to beige |
| InChI | 1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2 |
| InChIKey | ALQFAGFPQCBPED-UHFFFAOYSA-N |
| SMILES | O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(C4=CC=CC=C43)CCCCCF |
| FDA UNII | TBJ0966F1O |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H331-H301 | |||||||||
| Precautionary statements | P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| target organs | Central nervous system | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | STOT SE 3 | |||||||||
| DEA Controlled Substances | CSCN: 7201 CSA SCH: Schedule I NARC: No |
|||||||||
| NFPA 704 |
|
AM2201 price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3504 | AM-2201 ≥98% (HPLC) | 335161-24-5 | 5MG | $131 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML3504 | AM-2201 ≥98% (HPLC) | 335161-24-5 | 25MG | $530 | 2026-04-30 | Buy |
| Cayman Chemical | 10707 | AM2201 ≥98% | 335161-24-5 | 1mg | $90 | 2026-04-30 | Buy |
| Cayman Chemical | 27043 | AM2201 (CRM) | 335161-24-5 | 1mg | $160 | 2026-04-30 | Buy |
| Cayman Chemical | 10707 | AM2201 ≥98% | 335161-24-5 | 5mg | $219 | 2026-04-30 | Buy |
AM2201 Chemical Properties, Uses, Production
Description
AM2201 (Item No. 10707) is an analytical reference material characterized as a synthetic cannabinoid. AM2201 is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
Chemical Properties
Pale Yellow Solid
Uses
It is a drug which acts as a potent but unselective agonist for the cannabinoid receptor CB1 or CB2.
Uses
AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively. The physiological actions and metabolism of AM2201 have not been characterized. This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.[Cayman Chemical]
Definition
ChEBI: AM2201 is an indolecarboxamide.
References
[1] A K DUTTA. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs).[J]. Bioorganic & Medicinal Chemistry, 1997, 5 8: 1591-1600. DOI: 10.1016/s0968-0896(97)00111-9
[2] BYUNGSUK CHO . Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair[J]. Forensic science international, 2020, 306: Article 110058. DOI: 10.1016/j.forsciint.2019.110058
[3] MICHAEL A. MARINO M.S. Rapid Identification of Synthetic Cannabinoids in Herbal Incenses with DART-MS and NMR[J]. Journal of forensic sciences, 2015, 61 S1: S82-S91. DOI: 10.1111/1556-4029.12932
[4] PH.D. L A C. Quantitation of Synthetic Cannabinoids in Plant Materials Using High Performance Liquid Chromatography with UV Detection (Validated Method)[J]. Journal of forensic sciences, 2015, 60 5: 1171-1181. DOI: 10.1111/1556-4029.12795
