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(S)-N-Fmoc-2-(2'-propylenyl)alanine

CAS No.
288617-71-0
Chemical Name:
(S)-N-Fmoc-2-(2'-propylenyl)alanine
Synonyms
Fmoc-alpha-All-D-Ala-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine;(S)-N-Fmoc-2-(2'-propenyl)alanine
CBNumber:
CB02485702
Molecular Formula:
C21H21NO4
Molecular Weight:
351.4
MDL Number:
MFCD02682444
MOL File:
288617-71-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

(S)-N-Fmoc-2-(2'-propylenyl)alanine Properties

Boiling point 564.3±45.0 °C(Predicted)
Density 1.224
storage temp. Inert atmosphere,Store in freezer, under -20°C
form liquid
pka 3.81±0.11(Predicted)
color pale yellow
Major Application peptide synthesis
InChI InChI=1S/C21H21NO4/c1-3-12-21(2,19(23)24)22-20(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h3-11,18H,1,12-13H2,2H3,(H,22,25)(H,23,24)/t21-/m0/s1
InChIKey FNCSRFHDUZYOCR-NRFANRHFSA-N
SMILES C(O)(=O)[C@](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)(C)CC=C
UNSPSC Code 12352200
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273
Hazard Codes  N
Risk Statements  50
Safety Statements  61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
TSCA  No
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Acute 1

(S)-N-Fmoc-2-(2'-propylenyl)alanine price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine Asreported 288617-71-0 25mg $333 2026-06-03 Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine Asreported 288617-71-0 50mg $480 2026-06-03 Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine Asreported 288617-71-0 100mg $648 2026-06-03 Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine Asreported 288617-71-0 250mg $775 2026-06-03 Buy
Usbiological 278035 Fmoc-alpha-methyl-L-allylglycine Asreported 288617-71-0 500mg $1034 2026-06-03 Buy
Product number Packaging Price Buy
278035 25mg $333 Buy
278035 50mg $480 Buy
278035 100mg $648 Buy
278035 250mg $775 Buy
278035 500mg $1034 Buy

(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemical Properties, Uses, Production

Uses

Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

(S)-N-Fmoc-2-(2'-propylenyl)alanine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 80)
Supplier Tel Email Country ProdList Advantage
Langfang Kaimeikesi BiotechnologyCo.Ltd 15901279280; 15901279280 4574688522@qq.com China 480 58
Okeanos Tech Co,. Ltd. 010-62651721 18610486005 minghui.yu@okeanos.com.cn China 495 60
Suzhou haiyu Biochem Industrial Co., LTD 512-68097639 18013585858 744942877@qq.com China 915 62
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai Hisi bio-pharmaceutical Co. Ltd. +86-21-67228373 18939730372 Hisibio@hotmail.com China 40 55

View Latest Price from (S)-N-Fmoc-2-(2'-propylenyl)alanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-alpha-allyl-L-alanine pictures 2026-07-15 Fmoc-alpha-allyl-L-alanine
288617-71-0
$33.00-73.00 10g TargetMol Chemicals Inc.

(S)-N-Fmoc-2-(2'-propylenyl)alanine Spectrum

(S)-N-Fmoc-2-(2'-propylenyl)alanine (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid (S)-N-Fmoc-alpha-allylalanine (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine Fmoc-alpha-methyl-L-allylglycine (S)-N-FMOC-Α-ALLYLALANINE (S)-N-Fmoc-α-2-n-propenylalanine Fmoc-(S)-2-(2-propenyl)alanine Fmoc-(S)-2-(2-propenyl)Ala-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH Fmoc-alpha-All-D-Ala-OH (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid (S)-N-Fmoc-2-(2'-propenyl)alanine (2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid (S)-N-Fmoc-A-Allylalanine 4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)- N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine Fmoc-α-Me-Gly(Allyl)-OH Fmoc-(S)-2-(2-propenyl)Ala-OH (S)-2-(Fmoc-amino)-2-methyl-4-pentenoic Acid 288617-71-0 α-Methyl Amino Acids