(S)-N-Fmoc-2-(2'-propylenyl)alanine
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- CAS-Nr.
- 288617-71-0
- Englisch Name:
- (S)-N-Fmoc-2-(2'-propylenyl)alanine
- Synonyma:
- Fmoc-alpha-All-D-Ala-OH;Fmoc-α-Me-Gly(Allyl)-OH;(S)-N-FMOC-Α-ALLYLALANINE;(S)-N-Fmoc-A-Allylalanine;(S)-N-Fmoc-alpha-allylalanine;Fmoc-(S)-2-(2-propenyl)Ala-OH;Fmoc-(S)-2-(2-propenyl)alanine;(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-alpha-methyl-L-allylglycine;(S)-N-Fmoc-2-(2'-propenyl)alanine
- CBNumber:
- CB02485702
- Summenformel:
- C21H21NO4
- Molgewicht:
- 351.4
- MOL-Datei:
- 288617-71-0.mol
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Eigenschaften
- Siedepunkt:
- 564.3±45.0 °C(Predicted)
- Dichte
- 1.224
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- Aggregatzustand
- liquid
- pka
- 3.81±0.11(Predicted)
- Farbe
- pale yellow
- InChI
- InChI=1S/C21H21NO4/c1-3-12-21(2,19(23)24)22-20(25)26-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h3-11,18H,1,12-13H2,2H3,(H,22,25)(H,23,24)/t21-/m0/s1
- InChIKey
- FNCSRFHDUZYOCR-NRFANRHFSA-N
- SMILES
- C(O)(=O)[C@](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)(C)CC=C
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
N |
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| R-Sätze: |
50 |
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| S-Sätze: |
61 |
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| RIDADR |
UN 3077 9 / PGIII |
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| WGK Germany |
3 |
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| TSCA |
No |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gewässergefährdend |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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(S)-N-Fmoc-2-(2'-propylenyl)alanine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
(S)-N-Fmoc-2-(2'-propylenyl)alanine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-N-Fmoc-2-(2'-propylenyl)alanine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 76)Lieferanten
- (S)-N-Fmoc-2-(2'-propylenyl)alanine
- (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-4-pentenoic acid
- (S)-N-Fmoc-alpha-allylalanine
- (S)-N-(9-Fluorenylmethylcarbamate)-2-(2'-propylenyl)alanine
- Fmoc-alpha-methyl-L-allylglycine
- (S)-N-FMOC-Α-ALLYLALANINE
- (S)-N-Fmoc-α-2-n-propenylalanine
- Fmoc-(S)-2-(2-propenyl)alanine
- Fmoc-(S)-2-(2-propenyl)Ala-OH
- (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-Gly(Allyl)-OH
- Fmoc-alpha-All-D-Ala-OH
- (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpent-4-enoic acid
- (S)-N-Fmoc-2-(2'-propenyl)alanine
- (2S)-2-(Fmoc-amino)-2-methyl-4-pentenoic acid
- (S)-N-Fmoc-A-Allylalanine
- 4-Pentenoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-, (2S)-
- N-α-(9-Fluorenylmethoxycarbonyl)-α-methyl-L-α-allylglycine
- Fmoc-α-Me-Gly(Allyl)-OH
- Fmoc-(S)-2-(2-propenyl)Ala-OH
- (S)-2-(Fmoc-amino)-2-methyl-4-pentenoic Acid
- 288617-71-0
- α-Methyl Amino Acids
