methyl 2-(4-bromo-2-fluorophenyl)acetate
- CAS No.
- 193290-19-6
- Chemical Name:
- methyl 2-(4-bromo-2-fluorophenyl)acetate
- Synonyms
- Methyl 2-(4-bromo-2-fluorophenyl);Methyl 4-bromo-2-fluorophenylacetate;methyl 2-(4-bromo-2-fluorophenyl)acetate;Methyl 4-broMo-2-fluorophenylacetate, 96%;4-bromo-2-fluorophenylacetic acid methyl ester;Benzeneacetic acid, 4-bromo-2-fluoro-, methyl ester
- CBNumber:
- CB02512895
- Molecular Formula:
- C9H8BrFO2
- Molecular Weight:
- 247.06
- MDL Number:
- MFCD20483545
- MOL File:
- 193290-19-6.mol
- MSDS File:
- SDS
| Boiling point | 265.4±25.0 °C(Predicted) |
|---|---|
| Density | 1.519±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Solid |
| Appearance | Colorless to light yellow Liquid |
| CAS DataBase Reference | 193290-19-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2918300090 | |||||||||
| NFPA 704 |
|
methyl 2-(4-bromo-2-fluorophenyl)acetate price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC510106 | Methyl 4-bromo-2-fluorophenylacetate 98% | 193290-19-6 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC510106 | Methyl 4-bromo-2-fluorophenylacetate 98% | 193290-19-6 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC510106 | Methyl 4-bromo-2-fluorophenylacetate 98% | 193290-19-6 | 5g | $32 | 2026-06-04 | Buy |
| Apolloscientific | PC510106 | Methyl 4-bromo-2-fluorophenylacetate 98% | 193290-19-6 | 10g | $51 | 2026-06-04 | Buy |
| Apolloscientific | PC510106 | Methyl 4-bromo-2-fluorophenylacetate 98% | 193290-19-6 | 25g | $115 | 2026-06-04 | Buy |
methyl 2-(4-bromo-2-fluorophenyl)acetate Chemical Properties,Uses,Production
Synthesis
67-56-1
114897-92-6
193290-19-6
The general procedure for the synthesis of methyl 2-fluoro-4-bromophenylacetate from methanol and 2-fluoro-4-bromophenylacetic acid was as follows: a mixture of 2-fluoro-4-bromophenylacetic acid (20.2 g, 86.6 mmol) and concentrated sulfuric acid (7 mL) in methanol (200 mL) was heated and refluxed for 18 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in dichloromethane (200 mL), washed sequentially with saturated sodium bicarbonate solution and brine, and the organic phase was dried with anhydrous sodium sulfate. After filtration, the organic phase was concentrated under reduced pressure to give methyl 2-fluoro-4-bromophenylacetate (21.1 g, 99% yield) as a brown oil. Mass spectrum (ESI): m/z = 280.1 [M + H]+.
References
[1] Patent: WO2017/108723, 2017, A2. Location in patent: Page/Page column 225; 226
[2] Patent: US2014/194383, 2014, A1. Location in patent: Paragraph 0386-0388; 0390
[3] Patent: WO2014/141187, 2014, A1. Location in patent: Page/Page column 54; 55
[4] Patent: WO2016/38519, 2016, A1. Location in patent: Page/Page column 36; 37
[5] Patent: WO2016/38552, 2016, A1. Location in patent: Page/Page column 51
methyl 2-(4-bromo-2-fluorophenyl)acetate Preparation Products And Raw materials
Raw materials
Preparation Products
methyl 2-(4-bromo-2-fluorophenyl)acetate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
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| Aikon International Limited | 025-66113011 19370895928 | qzhang@aikonchem.com | China | 15390 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
