1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- CAS No.
- 649736-31-2
- Chemical Name:
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
- Synonyms
- CEDI-005;FMX15115-A4;1-(2-Fluoro-3-hydroxy-6-nitrophenyl);2-Fluoro-3-hydroxy-6-nitrophenylacetone;1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one;2-Propanone, 1-(2-fluoro-3-hydroxy-6-nitrophenyl)-
- CBNumber:
- CB02514086
- Molecular Formula:
- C9H8FNO4
- Molecular Weight:
- 213.16
- MDL Number:
- MFCD11869874
- MOL File:
- 649736-31-2.mol
- MSDS File:
- SDS
| Boiling point | 353.0±42.0 °C(Predicted) |
|---|---|
| Density | 1.417±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 5.58±0.24(Predicted) |
| form | Solid |
| InChI | InChI=1S/C9H8FNO4/c1-5(12)4-6-7(11(14)15)2-3-8(13)9(6)10/h2-3,13H,4H2,1H3 |
| InChIKey | IPRZVDNMKMONNN-UHFFFAOYSA-N |
| SMILES | C(C1=C([N+]([O-])=O)C=CC(O)=C1F)C(=O)C |
| CAS DataBase Reference | 649736-31-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2914790090 | |||||||||
| NFPA 704 |
|
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC51375 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one ≥95% | 649736-31-2 | 250mg | $58 | 2026-06-04 | Buy |
| Apolloscientific | PC51375 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one ≥95% | 649736-31-2 | 1g | $137 | 2026-06-04 | Buy |
| Matrix Scientific | 143736 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one | 649736-31-2 | 1.00g | $1458 | 2026-05-18 | Buy |
| Matrix Scientific | 143736 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one | 649736-31-2 | 5.00g | $2916 | 2026-05-18 | Buy |
| Synthonix | F24726 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 97% | 649736-31-2 | 250mg | $150 | 2026-05-06 | Buy |
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Chemical Properties, Uses, Production
Uses
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one (cas# 649736-31-2) is a useful research chemical.
Synthesis
121247-16-3
649736-31-2
Step 3b: A mixture of 1-(2,3-difluoro-6-nitrophenyl)propan-2-one (Compound 302, 4.30 g, 0.02 mol), sodium acetate (AcONa, 1.72 g, 0.021 mol) and N,N-dimethylformamide (DMF, 40 mL) was stirred and reacted for 12 hours at 100 °C. After completion of the reaction, the mixture was filtered and the solvent was removed by distillation under reduced pressure. The residue was extracted with ethyl acetate (100 mL) and the organic layer was washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO) and concentrated. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether = 1/1) to afford 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one (Compound 303, 2.3 g, 54%) as a light yellow solid.LCMS: 214 [M + 1] ; 1H NMR (DMSO-d6): δ 2.30 (s, 3H), 4.26 (s, 2H), 7.67 (m, 1H), 8.05 (m, 1H).
References
[1] Patent: US2009/76044, 2009, A1. Location in patent: Page/Page column 27-28
[2] Organic Process Research and Development, 2014, vol. 18, # 1, p. 89 - 102
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Preparation Products And Raw materials
1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CHANGZHOU GARDE PHARMTECH CO.,LTD | 18006124028 | gardepharm@163.com | China | 119 | 58 |
| Hunan Eurasian Pharmaceutical Co. Ltd. | 0592-5789919 13328776692 | 2851802018@qq.com;2851802016@qq.com | China | 88 | 58 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jinan Trio PharmaTech Co., Ltd. | 0531-88811783 | sales@trio-pharmatech.com | China | 1856 | 62 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 | sales@fartop.net | China | 2227 | 55 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451683 15021268886 | sales@arborchemical.com | China | 837 | 55 |
| Shanghai Synteam Biochem CO.,ltd | +86-021-58380978 13482386415 | info@systeambc.com | China | 897 | 50 |
| Hangzhou Milestone Pharmtech Co., Ltd. | 0571-82896630 18969958410 | sales_hz@milestonepharmtech.com | China | 4908 | 55 |
| Hangzhou Cheminspire Technology Co., Ltd. | 0571-89081561; 10006559855 | info@cheminspire.com | China | 412 | 58 |
View Latest Price from 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-08-07 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
|
1g | 99 | 100kg | Shanghai VastPro Technology Development Co., Ltd. | ||
 |
2020-02-26 | 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
|
1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
- $0.00
- 99
- Shanghai VastPro Technology Development Co., Ltd.
-
- 1-(2-Fluoro-3-hydroxy-6-nitrophenyl)propan-2-one
649736-31-2
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
