PLEIOTROPHIN, HUMAN
- CAS No.
- Chemical Name:
- PLEIOTROPHIN, HUMAN
- Synonyms
- PTN;HARP;HBNF;HBBM;HBGF8;NEGF1;HBNF1;OSF-1;ANKS4B;HB-GAM
- CBNumber:
- CB0253736
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01324256
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| Storage Class | 10 - Combustible liquids |
PLEIOTROPHIN, HUMAN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3143 | Pleiotrophin human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 20 μg | $414 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB1302033 | ANTI-ANKS4B (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400 μL | $532 | 2026-04-30 | Buy | |
| Sigma-Aldrich | P5333 | Pleiotrophin human ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture | 50 μg | $649 | 2026-04-30 | Buy | |
| Usbiological | 549363 | Pleiotrophin PurifiedbyProteinAandpeptideaffinitychromatography. | 200ul | $559 | 2026-06-03 | Buy | |
| Usbiological | 549362 | Pleiotrophin PurifiedbyProteinAandpeptideaffinitychromatography. | 200ul | $581 | 2026-06-03 | Buy |
PLEIOTROPHIN, HUMAN Chemical Properties, Uses, Production
Description
Pleiotrophin Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 136 amino acids and having a molecular mass of 15.3kDa.
The Pleiotrophin is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Pleiotrophin (Osteoblast-Specific Factor-1, OSF-1) contains 136 amino acid residues. The sequence is very rich in cationic amino acids (24% of the residues); lysine cluster sequences are found in the N-terminal and C-terminal ends of the structure.
The OSF-1 gene was shown by Northern blotting analysis to be expressed in mouse calvarial osteoblast-enriched cells and in mouse brain tissues, but not in thymus, spleen, kidney, liver, lung, testis or heart. Pleiotrophin has the ability to promote adhesion, migration, expansion, and differentiation of human osteoprogenitor cells. In addition to certain types of cancer, the embryonic growth and differentiation factor pleiotrophin is found also in adults in inflammatory diseases. In osteoarthritis, pleiotrophin is especially expressed in early stages, and its concentrations in the synovial fluid could serve as a marker for the progress of the disease. Pleitrophin might be involved in cartilage repair in osteoarthritis, in particular, in earlier stages.
PLEIOTROPHIN, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
PLEIOTROPHIN, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 13675144456 | alan.chow@synzest.com | China | 9467 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1592 | 58 |
| Shanghai Yubo Biotechnology Co., Ltd | 021-60514606 18321282235 | sale1@shybsw.net | China | 8165 | 58 |
| shlmai | 021-67680335 13052188602 | sale1@shlmai.net | China | 10000 | 58 |
