ChemicalBook >> CAS DataBase List >>DOTA-mono-NHS tris(t-Bu ester)
DOTA-mono-NHS tris(t-Bu ester)
- CAS No.
- 819869-77-7
- Chemical Name:
- DOTA-mono-NHS tris(t-Bu ester)
- Synonyms
- Tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate;DOTA-(COOt-Bu)3-NHS;DOTA-tris-tBu-ester NHS;DOTA tris(tBu)ester NHS ester;DOTA-Mono-NHS-tris(t-Bu ester);DOTA-mono-NHS-tris(t-Butyl ester);DOTA-mono-NHS-tris(t-Bu ester)(B-270);2-[1, 4, 7, 10-Tetraazacyclododecane-4, 7, 10-tris(t-butyl acetate)I-pentanedioic acid-1-t-butyl ester;1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 4,7,10-tris(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester;2,2',2''-(6-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1-oxa-2,6,9,12-tetraazacyclotridecane-2,9,12-triyl)triacetic acid
- CBNumber:
- CB02561015
- Molecular Formula:
- C32H55N5O10
- Molecular Weight:
- 669.81
- MDL Number:
- MOL File:
- 819869-77-7.mol
- MSDS File:
- SDS
Last updated:2026-07-16 07:06:08
| Product description | Number | Pack Size | Price |
| DOTA-tris(tBu)ester NHS ester ≥98% | CS-0133217 | 250mg | $59 |
| DOTA-tris(tBu)ester NHS ester ≥98% | CS-0133217 | 1g | $93 |
| DOTA-tris(tBu)ester NHS ester ≥98% | CS-0133217 | 5g | $160 |
| DOTA-tris(tBu)ester NHS ester ≥98% | CS-0133217 | 10g | $282 |
| DOTA-tris(tBu)ester NHS ester ≥98% | CS-0133217 | 25g | $446 |
| Boiling point | 686.8±65.0 °C(Predicted) |
|---|---|
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light |
| solubility | DMSO, DMF, acetonitrile |
| pka | 5.49±0.20(Predicted) |
| form | Solid |
| color | White to off-white |
| Appearance | white solid |
| InChIKey | XIICJKXKEDCZEE-UHFFFAOYSA-N |
| SMILES | N1(CC(ON2C(=O)CCC2=O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P302+P352 |
DOTA-mono-NHS tris(t-Bu ester) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0133217 | DOTA-tris(tBu)ester NHS ester ≥98% | 819869-77-7 | 250mg | $59 | 2026-06-04 | Buy |
| ChemScene | CS-0133217 | DOTA-tris(tBu)ester NHS ester ≥98% | 819869-77-7 | 1g | $93 | 2026-06-04 | Buy |
| ChemScene | CS-0133217 | DOTA-tris(tBu)ester NHS ester ≥98% | 819869-77-7 | 5g | $160 | 2026-06-04 | Buy |
| ChemScene | CS-0133217 | DOTA-tris(tBu)ester NHS ester ≥98% | 819869-77-7 | 10g | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0133217 | DOTA-tris(tBu)ester NHS ester ≥98% | 819869-77-7 | 25g | $446 | 2026-06-04 | Buy |
DOTA-mono-NHS tris(t-Bu ester) Chemical Properties,Uses,Production
Description
DOTA (dodecane tetraacetic acid, also known as tetraxetan) is a complexing agent, especially for lanthanide ions. DOTA-NHS ester is a bifunctional linker containing chelating and N-hydroxysuccinimide (NHS) ester groups for conjugation with amine-containing biomolecules.
DOTA-NHS ester can be used to label radiotherapeutic agents or imaging probes and detect labeled tumors with PET, SPECT, and CT methods.
Uses
DOTA-tris(tBu)ester NHS ester is a derivative of DOTA for the labeling of peptides and antibodies[1].
References
[1] Wngler C, et, al. Improved syntheses and applicability of different DOTA building blocks for multiply derivatized scaffolds. Bioorg Med Chem. 2008 Mar 1; 16(5): 2606-16. DOI:10.1016/j.bmc.2007.11.044
Synthesis of DOTA-mono-NHS tris(t-Bu ester) from N-Hydroxysuccinimide and TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
DOTA-mono-NHS tris(t-Bu ester) Preparation Products And Raw materials
Raw materials
Preparation Products
DOTA-mono-NHS tris(t-Bu ester) Suppliers
Global( 97)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14036 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9636 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1824 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9935 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Chongqing jooe co., ltd | +86-15223382610 | info@jooe.com | China | 15967 | 58 |
| PuriPharm Co., ltd. | +86-0572-2745768 +86-13816075732 | sales@puripharm.com | China | 1008 | 58 |
View Lastest Price from DOTA-mono-NHS tris(t-Bu ester) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | DOTA-tris(tBu)ester NHS ester
819869-77-7
|
10g | TargetMol Chemicals Inc. | ||||
 |
2025-06-07 | DOTA-(COOt-Bu)3-NHS
819869-77-7
|
500mg | >95.00% | 500mg | Xian confluore Biological Technology Co., Ltd. | ||
 |
2022-01-15 | DOTA-tris-tBu-esterNHS
819869-77-7
|
1KG | 98.5% | 100 tons | Honest Joy Holdings Limited |
-
- DOTA-tris(tBu)ester NHS ester
819869-77-7
- $0.00
- TargetMol Chemicals Inc.
-
- DOTA-(COOt-Bu)3-NHS
819869-77-7
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
-
- DOTA-tris-tBu-esterNHS
819869-77-7
- $0.00
- 98.5%
- Honest Joy Holdings Limited
819869-77-7(DOTA-mono-NHS tris(t-Bu ester))Related Search:
DOTA-mono-NHS-tris(t-Bu ester)(B-270)
DOTA-Mono-NHS-tris(t-Bu ester)
1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-, tris(1,1-diMethylethyl) ester
DOTA-tris-tBu-ester NHS
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 4,7,10-tris(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
DOTA tris(tBu)ester NHS ester
2-[1, 4, 7, 10-Tetraazacyclododecane-4, 7, 10-tris(t-butyl acetate)I-pentanedioic acid-1-t-butyl ester
DOTA-mono-NHS-tris(t-Butyl ester)
DOTA-(COOt-Bu)3-NHS
Tri-tert-butyl 2,2'',2''''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
tert-butyl 2-{4,7-bis[2-(tert-butoxy)-2-oxoethyl]-10-{2-[(2,5-dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}-1,4,7,10-tetraazacyclododecan-1-yl}acetate
2,2',2''-(10-(2-((2,5-dioxypyrolidine-1-yl)oxy)-2-oxyethyl)-1,4,7,10-tetrazacyclodecane-1,4,7-triyl)triacetic acidtritertbutyl ester
2,2',2''-(6-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1-oxa-2,6,9,12-tetraazacyclotridecane-2,9,12-triyl)triacetic acid
Tri-tert-butyl 2,2',2''-(10-(2-((2,5-dioxopyrrolidin-1-yl)oxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
819869-77-7
C32H55N5O10
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