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N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate

CAS No.
14933-08-5
Chemical Name:
N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate
Synonyms
SB-12;SB3-12;NDA-d25;RALUFON DL;Anzergent 3-12;RALUFON (R) DL;LAURYL SULTAINE;RALUFON (R) DCH;SULFOBETAINE-12;zwittergent3-12
CBNumber:
CB0258625
Molecular Formula:
C17H37NO3S
Molecular Weight:
335.55
MDL Number:
MFCD00036909
MOL File:
14933-08-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate Properties

Melting point 250-260 °C (dec.)
Flash point 110 °C
storage temp. Inert atmosphere,Room Temperature
solubility H2O: 1 M at 20 °C, clear, colorless
form Powder
color white
Water Solubility Soluble at 1M in water.
Sensitive Hygroscopic
BRN 4145308
Stability Hygroscopic
Cosmetics Ingredients Functions VISCOSITY CONTROLLING
ANTISTATIC
SURFACTANT - CLEANSING
HAIR CONDITIONING
SURFACTANT - FOAM BOOSTING
CLEANSING
SKIN CONDITIONING
Cosmetic Ingredient Review (CIR) N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (14933-08-5)
InChI InChI=1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3
InChIKey QTBGUOACROERKZ-UHFFFAOYSA-N
SMILES C(CCS([O-])(=O)=O)[N+](C)(C)CCCCCCCCCCCC
LogP -1.910 (est)
CAS DataBase Reference 14933-08-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII R6P3KW3E8U
EPA Substance Registry System N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (14933-08-5)
UNSPSC Code 12161902
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  C,Xi,Xn
Risk Statements  34-36/37/38-20/21/22
Safety Statements  26-36/37/39-45-36-24/25-22-37/39
RIDADR  UN 3261 8/PG 3
WGK Germany  3
3
TSCA  TSCA listed
HS Code  29239000
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 693015 ZWITTERGENT 3-12 Detergent - CAS 14933-08-5 - Calbiochem Asyntheticzwitterionicdetergent,whichunlikeotheramphotericsurfactants,r 14933-08-5 5G $207 2026-04-30 Buy
Sigma-Aldrich 693015 ZWITTERGENT 3-12 Detergent - CAS 14933-08-5 - Calbiochem Asyntheticzwitterionicdetergent,whichunlikeotheramphotericsurfactants,r 14933-08-5 25g $709 2026-04-30 Buy
Sigma-Aldrich 40232 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate ≥97.0% (dried material, CHN) 14933-08-5 50g $322 2026-04-30 Buy
Sigma-Aldrich 40232 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate ≥97.0% (dried material, CHN) 14933-08-5 250g $1340 2026-04-30 Buy
TCI Chemical D2332 Dodecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt >98.0%(N) 14933-08-5 25g $100 2026-04-30 Buy
Product number Packaging Price Buy
693015 5G $207 Buy
693015 25g $709 Buy
40232 50g $322 Buy
40232 250g $1340 Buy
D2332 25g $100 Buy

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate Chemical Properties, Uses, Production

Uses

Widely used as a surfactant in nanomaterial synthesis for the preparation of metal and mixed metallic particles, Also, for use in biochemical materials.

Chemical Properties

White powder

Uses

A component of alkyl sulfobetaine-type detergents.

Uses

Zwittergent 3-12 Detergent is useful for protein solubilization. Used to remove target substances from solution via foam separation method.

Uses

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate has been used in a study to assess protein structural change in a mixed system of ionic and zwitterionic surfactants. It has also been used in a study to investigate the interaction between ionic liquid and zwitterionic surfactant.

Definition

ChEBI: An ammonium betaine in which the ammonium nitrogen is substituted by dodecyl, 3-sulfatopropyl and two methyl groups.

General Description

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate is a zwitterionic surfactant.

Synthesis

1,3-Propanesultone

1120-71-4

N,N-Dimethyldodecylamine

112-18-5

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate

14933-08-5

The general procedure for the synthesis of 3-(N,N-dimethyldodecylammonium) propane sulfonate from 1,3-propanesulfonolactone and dodecyldimethyl tertiary amine was as follows: N,N-dimethyldodecylamine (50 mmol) was mixed with 1,3-propanesulfonolactone (52 mmol) in ethanol (20 mL), and the reaction was stirred at room temperature for 24 hours. After completion of the reaction, the reaction system was cooled to 0-5 °C in an ice-water bath, and the resulting precipitate was collected by filtration, washed with ether, and subsequently dried under vacuum at 65 °C for 8 h. The target product, 3-(N,N-dimethyldodecylammonium) propanesulfonate (1), was obtained in 95% yield.

References

[1] Monatshefte fur Chemie, 2009, vol. 140, # 11, p. 1325 - 1329
[2] Catalysis Communications, 2015, vol. 69, p. 5 - 10
[3] Journal of Surfactants and Detergents, 2011, vol. 14, # 1, p. 31 - 35
[4] Synthesis, 2002, # 16, p. 2431 - 2439
[5] Journal of Physical Chemistry, 1984, vol. 88, # 25, p. 6357 - 6362

N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 310)
Supplier Tel Email Country ProdList Advantage
Shanghai klamar Reagent Co., LTD 4001650900 13817534909 sales@klamar-reagent.com China 10711 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79

View Latest Price from N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate pictures 2026-09-15 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate
14933-08-5
1KG 99% 3500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Sulfobetaine-12 pictures 2026-07-16 Sulfobetaine-12
14933-08-5
$45.00 99.80% 10g TargetMol Chemicals Inc.
N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate pictures 2025-05-23 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate
14933-08-5
$45.00 1kg 99% 20 tons Hebei Zhuanglai Chemical Trading Co Ltd
3-(DodecyldiMethylaMMonio)propane-1-sulfonate 3-(N,N- twoMethyl twelvealkyl aMMoniuM)propanesulfonate 3-(Dodecyldimethylammonio)propanesulfonate solution Detergent Screening Solution 46/Fluka kit no 66317 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate solution 3-(Lauryldimethylammonio)propane-1-sulfonate Anzergent 3-12 N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-P 3-(Dodecyldimethylammonio) N,N-DIMETHYL-N-DODECYL-N-(3-SULFOPROPYL)AMMONIUM BETAINE N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE n-Dodecyldimethyl(3-sulfopropyl)ammonium hydroxide RALUFON DL dodecyldimethyl(3-sulphonatopropyl)ammonium 3-Sulphopropyl dodecyl dimethylammonium betaine LAURYL SULTAINE Dimethyl(3-sulfopropyl)tetradecylammonium hydroxyde N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPA NESULFONAT Sb-12N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Dodecyl-N,N-dimethylammonio-3-propane sulfonate N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE,ULTRAPURE N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULPHONATE LAURYLSULPHOBETAINE DODECYLDIMETHYLAMMONIUMPROPANESULPHONATE N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate (Sulfobetaine 12) N-DODECYL-N, N-DIMETHYL-3-AMMONIO-4-PROPASULFONATE N,N-Dimethyl-N-(3-sulfopropyl)-1-dodecanaminium, inner salt 3-(N,N-DIMETHYL)PROPANE SULFONATE(SDDAB) N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1- PROPANESULFONATE (SB-12) 3-[Dimethyl(dodecyl-d25)ammonio]propane-1-sulfonate N-(Dodecyl-d25)-N,N-dimethyl-3-ammonio-1-propanesulphonate N,N-Dimethyl-N-(3-sulfopropyl)-1-dodecanaminium-d25 Inner Salt NDA-d25 N-Dodecylsulfobetaine-d25 Zwittergent TM 12-d25 3-(dimethyldodecylammonio)propanesulfonate 3-(Dodecyldimethylammonio)propanesulfonate solution, 3-(Lauryldimethylammonio)propanesulfonate, 3-(N,N-Dimethyldodecylammonio)propanesulfonate, 3-(N,N-Dimethyllaurylammonio)propanesulfonate, Detergent Screening Solution 46/Fluka kit no 66317, N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate solution, Zwittergent(R) 3-12 N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate 30 mM solution N-DODECYL-N,N-DIMETHYLAMMONIO-3-PROPANE SULFONATE N-COCO-N,N-DIMETHYL-N-(3-SULFOPROPYL)AMMONIUM BETAINE RALUFON (R) DCH RALUFON (R) DL SULFOBETAINE-12 SULFOBETAINE SB 12 SB3-12 ZWITTERGENT 3-12 DETERGENT ZWITTERGENT(R) 3-08 ZWITTERGENT(R) 3-12 ZWITTERGENT(R) 3-12 DETERGENT 3-(DODECYLDIMETHYLAMMONIO)PROPANESULFONATE 3-(LAURYLDIMETHYLAMMONIO)PROPANESULFONATE 3-(N,N-DIMETHYLDODECYLAMMONIO)PROPANESULFONATE 3-(N,N-DIMETHYLLAURYLAMMONIO)PROPANESULFONATE 3-SULFOPROPYL DODECYL DIMETHYL AMMONIUM BETAINE LABOTEST-BB LT00453139 LAURYL SULFOBETAINE DODECYLDIMETHYL(3-SULFOPROPYL)AMMONIUM HYDROXIDE INNER SALT 1-dodecanaminium,n,n-dimethyl-n-(3-sulfopropyl)-,hydroxide,innersalt