1-Dodecanol
- CAS No.
- 112-53-8
- Chemical Name:
- 1-Dodecanol
- Synonyms
- LAURYL ALCOHOL;Fatty alcohol;DODECANOL;DODECAN-1-OL;lauryl;dodecyl;Pisol;DODECYL ALCOHOL;FEMA 2617;Lauric Alcohol
- CBNumber:
- CB1334632
- Molecular Formula:
- C12H26O
- Molecular Weight:
- 186.33
- MDL Number:
- MFCD00004753
- MOL File:
- 112-53-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 22-26 °C(lit.) |
|---|---|
| Boiling point | 260-262 °C(lit.) |
| Density | 0.833 g/mL at 25 °C(lit.) |
| vapor density | 7.4 (vs air) |
| vapor pressure | 0.1 mm Hg ( 20 °C) |
| refractive index |
n |
| FEMA | 2617 | LAURYL ALCOHOL |
| FLAVIS Number | 02.008 | Dodecan-1-ol |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | water: slightly soluble1g/L at 23°C |
| form | Liquid |
| pka | 15.20±0.10(Predicted) |
| color | APHA: ≤10 |
| Odor | Typical fatty alcohol odor; sweet. |
| Odor Type | waxy |
| biological source | synthetic |
| Viscosity | 11.251mm2/s |
| explosive limit | 4% |
| Water Solubility | insoluble |
| Specific Heat Capacity | Cp(liquid): 2.35 J/(g·K), at 25℃ |
| Thermal Conductivity | 0.167 W/(m·K) at 50 ℃ |
| JECFA Number | 109 |
| Merck | 14,3405 |
| BRN | 1738860 |
| Henry's Law Constant | 1.2×10-1 mol/(m3Pa) at 25℃, Brockbank (2013) |
| Dielectric constant | 6.5(24℃) |
| Cosmetics Ingredients Functions |
EMULSION STABILISING SURFACTANT - EMULSIFYING SKIN CONDITIONING - EMOLLIENT VISCOSITY CONTROLLING |
| InChI | 1S/C12H26O/c1-2-3-4-5-6-7-8-9-10-11-12-13/h13H,2-12H2,1H3 |
| InChIKey | LQZZUXJYWNFBMV-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCO |
| LogP | 5.4 at 23℃ |
| CAS DataBase Reference | 112-53-8(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | LAURYL ALCOHOL |
| FDA 21 CFR | 175.105; 175.300; 177.1200;177.1390; 178.3480 |
| EWG's Food Scores | 1 |
| FDA UNII | 178A96NLP2 |
| NIST Chemistry Reference | 1-Dodecanol(112-53-8) |
| EPA Substance Registry System | 1-Dodecanol (112-53-8) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H410 | |||||||||
| Precautionary statements | P264-P273-P280-P305+P351+P338-P337+P313-P391 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 38-50-50/53-36/38-36/37/38 | |||||||||
| Safety Statements | 61-37/39-29-26-60-36 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | JR5775000 | |||||||||
| Autoignition Temperature | 500 °F | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29051700 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 |
|||||||||
| Hazardous Substances Data | 112-53-8(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
1-Dodecanol price More Price(98)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 1 each | $58 | 2026-04-30 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 1kg | $82.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 4kg | $183 | 2026-04-30 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 8kg | $290 | 2026-04-30 | Buy |
| Sigma-Aldrich | W261718 | Lauryl alcohol ≥98%, FG | 112-53-8 | 20kg | $518 | 2026-04-30 | Buy |
1-Dodecanol Chemical Properties, Uses, Production
Chemical Properties
Lauryl alcohol has a characteristic fatty odor; unpleasant at high concentrations, but delicate and floral on dilution. 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a fatty, waxy flavor and is used in detergents, lubricating oils, and pharmaceuticals.
Physical properties
1-Dodecanol is a white low melting crystalline solid that has a melting point of 24°C.The air odor threshold for dodecyl alcohol (isomer not specified) is reported to be 7.1 ppb.
Occurrence
Reported found in the oil of Mexican lime and in the oil from flowers of Furcraea gigantean. Also reported found in apple, banana, sour cherry, citrus peel oils, melon, pineapple, potato, thymus, cheeses, butter, milk powder, chicken and beef fat, cooked pork, beer, whiskies, white wine, peanuts, beans, mushrooms, mango, coriander seed and leaf, rice, Bourbon vanilla, endive, crab, clam, Cape gooseberry, pawpaw and maté.
Uses
1-Dodecanol is used as a cosmetic, textile auxiliaries, synthetic oil, emulsifiers and flotation agent of raw materials, a detergent raw material, a foaming agent of the toothpaste.
Uses
1-Dodecanol is used in chemical formulations for a variety of purposes, including as an emulsion stabilizer, a skin-conditioning emollient, and a viscosity-increasing agent.
Definition
ChEBI: 1-Dodecanol is a fatty alcohol that is dodecane in which a hydrogen from one of the methyl groups is replaced by a hydroxy group. It is registered for use in apple and pear orchards as a Lepidopteran pheromone/sex attractant, used to disrupt the mating behaviour of certa n moths whose larvae destroy crops.
Preparation
Commercially 1-Dodecanol may be prepared by hydrogenation of lauric acid; normally employed as a replacement for the corresponding aldehyde.
Production Methods
1-Dodecanol (Lauryl alcohol) is produced commercially by the oxo process and from ethylene by the Ziegler process, which involves oxidation of trialkylaluminum compounds. It can also be produced by sodium reduction or high-pressure hydrogenation of esters of naturally occurring lauric acid.
Aroma threshold values
Detection: 73 to 820 ppb
Synthesis Reference(s)
Journal of the American Chemical Society, 108, p. 6036, 1986 DOI: 10.1021/ja00279a061
Tetrahedron Letters, 37, p. 3623, 1996 DOI: 10.1016/0040-4039(96)00652-1
General Description
Colorless thick liquid with a sweet odor. Floats on water. Freezing point is 75°F.
Reactivity Profile
Dodecyl alcohol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
Health Hazard
Liquid will cause burning of the eyes and may irritate skin.
Flammability and Explosibility
Non flammable
Safety Profile
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. A severe human skin irritant. Questionable carcinogen with experimental tumorigenic data. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use dry chemical, CO2. When heated to decomposition it emits acrid smoke and irritating fumes
Carcinogenicity
1-Dodecanol showed weak tumor-promoting activity when applied three times a week for 60 weeks to the skin of mice that had previously received an initiating dose of dimethylbenz[a]anthracene. Papillomas developed in 2 of 30 mice after 39 and 49 weeks of treatment.
Purification Methods
Crystallise dodecanol from aqueous EtOH, and distil it through a spinning-band column under vacuum. [Ford & Marvel Org Synth 10 62 1930, Beilstein 1 IV 1844.]
1-Dodecanol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of5
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Shanghai shengyue international trading co., ltd | 021-66690837 13166269258 | 2570384992@qq.com | China | 53 | 58 |
| Shanghai Kangluo New Material Technology Co., LTD | 021-021-51601195 19512239872 | 180800400@qq.com | China | 140 | 58 |
| Shanghai Wohua Chemical Co., Ltd. | 021-57681602-802 17302146015 | 2851602437@qq.com | China | 290 | 58 |
| Nantong Zhonghe Chemical New Materials Co., Ltd | 0513-85666561 15950816326 | 2369399482@qq.com | China | 9289 | 58 |
| Nantong Herun Biotechnology Co., Ltd | 18362409333 | 18362409333@139.com | China | 4999 | 58 |
| Wuhan Carnoss Technology Co., LTD | 18064039730 | 3127859172@qq.com | China | 6716 | 58 |
| shandongxinheng | 152-15269160605-0605 15269160605 | 15269160605@163.com | China | 986 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
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View Latest Price from 1-Dodecanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-09-17 | 1-Dodecanol
112-53-8
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-09-17 | 1-Dodecanol
112-53-8
|
1kg /Drum | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. | ||
 |
2026-09-17 | 1-Dodecanol
112-53-8
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- 1-Dodecanol
112-53-8
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- 1-Dodecanol
112-53-8
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
-
- 1-Dodecanol
112-53-8
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
