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19(S)-HETE

CAS No.
115461-40-0
Chemical Name:
19(S)-HETE
Synonyms
19(S)-HETE;19(S)-HETE Exclusive;XFUXZHQUWPFWPR-DZBJBCEBSA-N;19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-ETA;19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid;5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z,19S)-
CBNumber:
CB02589961
Molecular Formula:
C20H32O3
Molecular Weight:
320.47
MDL Number:
MFCD18427931
MOL File:
115461-40-0.mol
MSDS File:
SDS
Last updated:2026-04-21 17:10:26

19(S)-HETE Properties

Boiling point 477.3±45.0 °C(Predicted)
Density 0.984±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka 4.75±0.10(Predicted)

19(S)-HETE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007766 19(S)-HETE ≥98% 115461-40-0 25μg $161 2026-04-30 Buy
Cayman Chemical 10007766 19(S)-HETE ≥98% 115461-40-0 50μg $306 2026-04-30 Buy
Cayman Chemical 10007766 19(S)-HETE ≥98% 115461-40-0 100μg $578 2026-04-30 Buy
ChemScene CS-0374505 19(S)-HETE 115461-40-0 50??g $707 2026-06-04 Buy
Arctom HY-142972 19(S)-HETE 115461-40-0 50??g $621 2026-05-26 Buy
Product number Packaging Price Buy
10007766 25μg $161 Buy
10007766 50μg $306 Buy
10007766 100μg $578 Buy
CS-0374505 50??g $707 Buy
HY-142972 50??g $621 Buy

19(S)-HETE Chemical Properties, Uses, Production

Description

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.

Uses

19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels[1].

Definition

ChEBI: 19(S)-HETE is a HETE having a (19S)-hydroxy group and all-cis double bonds at positions 5, 8, 11 and 14. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,11,14-tetraenoic acid and an arachidonic acid.

References

[1] Tunaru S, et al. Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS One. 2016 Sep 23;11(9):e0163633. DOI:10.1371/journal.pone.0163633

19(S)-HETE Preparation Products And Raw materials

Raw materials

Preparation Products

19(S)-HETE Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
amyjet 4006800868;027-59626688 18771149750 sales@amyjet.com China 2909 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
SHANGHAI ZZBIO CO., LTD. 18019219489 18901678489 tech@zzbioco.com China 12062 58

View Latest Price from 19(S)-HETE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
19(S)-HETE pictures 2026-04-21 19(S)-HETE
115461-40-0
$987.00 10g TargetMol Chemicals Inc.
  • 19(S)-HETE pictures
  • 19(S)-HETE
    115461-40-0
  • $987.00
  • TargetMol Chemicals Inc.
19(S)-HETE XFUXZHQUWPFWPR-DZBJBCEBSA-N 19(S)-HETE Exclusive 5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z,19S)- 19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid 19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-ETA 115461-40-0