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19(S)-HETE

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19(S)-HETE manufacturers

  • 19(S)-HETE
  • 19(S)-HETE pictures
  • $987.00
  • 2026-04-21
  • CAS:115461-40-0
  • Purity:
  • Supply Ability: 10g
19(S)-HETE Basic information
Product Name:19(S)-HETE
Synonyms:19(S)-HETE;XFUXZHQUWPFWPR-DZBJBCEBSA-N;19(S)-HETE Exclusive;5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z,19S)-;19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid;19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-ETA
CAS:115461-40-0
MF:C20H32O3
MW:320.47
EINECS:
Product Categories:
Mol File:115461-40-0.mol
19(S)-HETE Structure
19(S)-HETE Chemical Properties
Boiling point 477.3±45.0 °C(Predicted)
density 0.984±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka4.75±0.10(Predicted)
Safety Information
MSDS Information
19(S)-HETE Usage And Synthesis
Description19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.
Uses19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels[1].
DefinitionChEBI: 19(S)-HETE is a HETE having a (19S)-hydroxy group and all-cis double bonds at positions 5, 8, 11 and 14. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,11,14-tetraenoic acid and an arachidonic acid.
References[1] Tunaru S, et al. Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS One. 2016 Sep 23;11(9):e0163633. DOI:10.1371/journal.pone.0163633
19(S)-HETE Preparation Products And Raw materials
Tag:19(S)-HETE(115461-40-0) Related Product Information
Ricinelaidicacid (17R,5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid 9-Octadecenoic acid, 12,13-dihydroxy-, (9Z,12S,13R)- Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic Acid POTASSIUM RICINOLEATE 10(Z),13(Z),16(Z)-Nonadecatrienoic acid