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ChemicalBook >> CAS DataBase List >>9,11-methane-epoxy Prostaglandin F1α

9,11-methane-epoxy Prostaglandin F1α

9,11-methane-epoxy Prostaglandin F1α Structure
9,11-methane-epoxy Prostaglandin F1α structure
CAS No.
72517-81-8
Chemical Name:
9,11-methane-epoxy Prostaglandin F1α
Synonyms
VGRVXLWYKKBTNM-KQMLLPOFSA-N;9,11-methane-epoxy Prostaglandin 1α;9,11-methane-epoxy Prostaglandin 1α;9,11-methane-epoxy Prostaglandin F1α;9,11-methane-epoxy Prostaglandin 1alpha;9,11-methane-epoxy Prostaglandin F1.alpha.;2-Oxabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, [1α,4α,5β,6α(1E,3S*)]- (9CI)
CBNumber:
CB02590123
Molecular Formula:
C21H36O4
Molecular Weight:
352.51
MDL Number:
MOL File:
72517-81-8.mol
MSDS File:
SDS
Last updated:2026-08-04 08:04:28
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9,11-methane-epoxy Prostaglandin F1α Properties

Boiling point 519.077±25.00 °C(Press: 760.00 Torr)(predicted)
Density 1.077±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
pka 4.777±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319-H336
Precautionary statements  P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

9,11-methane-epoxy Prostaglandin F1α price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 100μg $83 2026-04-30 Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 500μg $392 2026-04-30 Buy
Cayman Chemical 10007850 9,11-methane-epoxy Prostaglandin F1α ≥96% 72517-81-8 1mg $288 2021-12-16 Buy
Product number Packaging Price Buy
10007850 100μg $83 Buy
10007850 500μg $392 Buy
10007850 1mg $288 Buy

9,11-methane-epoxy Prostaglandin F1α Chemical Properties, Uses, Production

Description

Prostaglandin (PG) endoperoxides are intermediates in the biosynthesis of PGs, thromboxanes, and prostacyclin. The endoperoxides, PGH2 and PGG2, induce rapid and irreversible aggregation of human platelets.1 PGH1 and PGG1 are known to contract smooth muscle preparations, but are lacking in aggregatory effects. 9,11-methane-epoxy Prostaglandin F1α (9,11-methane-epoxy PGF1α) is a stable epoxymethano analog of PGH1 that produces a strong and dose-related aggregation of washed rabbit platelets (EC50 = 0.88 μM) and contraction of rabbit aortic strips (EC50 = 0.11 μM).1 9,11-methane-epoxy PGF1α induces contraction of guinea pig tracheas (EC50 = 3.4 μM) with a maximal contraction of about 60% of that caused by a submaximal dose of histamine.

References

1. Morita, A., Nishino, H., Hasegawa, K., et al. Biological activities of prostaglandin H1 analogs Prostaglandins 18(4),529-540(1979).

9,11-methane-epoxy Prostaglandin F1α Preparation Products And Raw materials

Raw materials

Preparation Products

9,11-methane-epoxy Prostaglandin F1α Suppliers

Global Suppliers ( 15)
Supplier Tel Email Country ProdList Advantage
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Supplier Advantage
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72517-81-8 (9,11-methane-epoxy Prostaglandin F1α) Related Search:

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9,11-methane-epoxy Prostaglandin F1α 9,11-methane-epoxy Prostaglandin 1α VGRVXLWYKKBTNM-KQMLLPOFSA-N 9,11-methane-epoxy Prostaglandin F1.alpha. 9,11-methane-epoxy Prostaglandin 1alpha 2-Oxabicyclo[2.2.1]heptane-5-heptanoic acid, 6-(3-hydroxy-1-octenyl)-, [1α,4α,5β,6α(1E,3S*)]- (9CI) 9,11-methane-epoxy Prostaglandin 1α 72517-81-8