Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate
- CAS No.
- 22955-77-7
- Chemical Name:
- Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate
- Synonyms
- methyl 1-indanone-2-carboxylate;Methyl 1-Oxoindane-2-carboxylate;1-oxy-2,3-dihydro-1H--2-methyl formate;methyl 3-oxo-1,2-dihydroindene-2-carboxylate;Methyl 2,3-dihydro-1-oxo-1H-indene-2-carboxylate;Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate;3-oxo-1,2-dihydroindene-2-carboxylic acid methyl ester;1H-Indene-2-carboxylic acid, 2,3-dihydro-1-oxo-, methyl ester
- CBNumber:
- CB02605908
- Molecular Formula:
- C11H10O3
- Molecular Weight:
- 190.2
- MDL Number:
- MOL File:
- 22955-77-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R175420 | 1-OXO-INDAN-2-CARBOXYLIC ACID METHYL ESTER AldrichCPR | 22955-77-7 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | R175420 | 1-OXO-INDAN-2-CARBOXYLIC ACID METHYL ESTER AldrichCPR | 22955-77-7 | 50MG | $179 | 2024-03-01 | Buy |
| TCI Chemical | M3689 | Methyl 1-Oxo-2,3-dihydro-1H-indene-2-carboxylate min. 98.0 % | 22955-77-7 | 250MG | $114 | 2026-04-30 | Buy |
| Matrix Scientific | 307019 | Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate | 22955-77-7 | 1.00g | $76 | 2026-05-19 | Buy |
| Matrix Scientific | 307019 | Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate | 22955-77-7 | 5.00g | $230 | 2026-05-19 | Buy |
Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate Chemical Properties, Uses, Production
Synthesis
25040-17-9
22955-77-7
Methyl 2-[3-(methoxy)-3-oxopropyl]benzoate (3.77 g, 16.98 mmol) was dissolved in anhydrous THF (75 mL) under argon protection. Under stirring, sodium hydride (2.04 g, 60% oil suspension, 50.9 mmol) was slowly added over 2 min. Subsequently, the reaction mixture was slowly heated to reflux. After 1 hour of reflux reaction, formation of a thick paste was observed. The reaction mixture was cooled to room temperature and quenched by adding water (1 mL) dropwise over 5 min. Next, the reaction mixture was acidified with 5 M hydrochloric acid (20 mL) and extracted twice with ethyl acetate. The organic phases were combined, dried with anhydrous magnesium sulfate, and subsequently concentrated under reduced pressure to give an oil. The oily substance was purified by silica gel column chromatography (70 g) using a 0-50% ethyl acetate/pentane gradient elution to afford methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate as a yellow oil (2.14 g, 66% yield), which solidified to a solid on standing. The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 7.79 (1H, d, J = 7.6 Hz), 7.63 (1H, dd, J = 7.6 and 7.6 Hz), 7.50 (1H, d, J = 7.6 Hz), 7.42 (1H, dd, J = 7.6 and 7.6 Hz), 3.80 (3H, s), 3.75 ( 1H, m), 3.60 (1H, m), 3.40 (1H, m).
References
[1] Patent: WO2010/57865, 2010, A1. Location in patent: Page/Page column 23-24
Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai D&B Biological Science and Technology Co.Ltd | 400-008-9730,021-54359730 400-008-9730 | info@chemxyz.com | China | 3642 | 60 |
| Shanghai PharmaPartner Co., Ltd. | 19983777532 | pharmabridge@163.com | China | 500 | 55 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9239 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| 9ding chemical ( Shanghai) Limited | 021-021-52271985 17721149837 | sales@9dingchem.com | China | 19780 | 60 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24650 | 60 |
| Shandong utilizing biological technology co., LTD | 18669728830 15966937598 | 3407650895@qq.com | China | 5185 | 58 |
View Latest Price from Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate
22955-77-7
|
$1.60-6.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate
22955-77-7
- $1.60-6.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
