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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine structure

CAS No.: 147116-67-4

Chemical Name:: (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine

Synonyms: Maropitant;Maropitan;CJ-11972);Horse's temple;Maropitant base;Maropitant (CJ11,972;Pafolacianine Impurity 5;Maropitant, 10 mM in DMSO;Maropitant intermediate 6;(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine

CBNumber:: CB02622781

Molecular Formula:: C32H40N2O

Molecular Weight:: 468.67

MDL Number:: MFCD25541735

MOL File:: 147116-67-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-22 15:57:46

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(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Properties

Boiling point	572.6±50.0 °C(Predicted)
Density	1.11±0.1 g/cm3(Predicted)
vapor pressure	0-0Pa at 20-25℃
storage temp.	Store at -20°C
solubility	DMSO : 33.33 mg/mL (71.12 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form	Solid:particulate/powder
pka	9.99±0.70(Predicted)
color	Off-white to yellow
InChIKey	OMPCVMLFFSQFIX-CONSDPRKSA-N
SMILES	N12CCC(CC1)[C@H](NCC1=CC(C(C)(C)C)=CC=C1OC)[C@@H]2C(C1=CC=CC=C1)C1=CC=CC=C1
LogP	3.1-7.2 at pH2-7.5
CAS DataBase Reference	147116-67-4
FDA UNII	4XE2T9H4DH
UNSPSC Code	51111800
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09
Signal word	Warning
Hazard statements	H410-H373-H317
Precautionary statements	P273-P391-P501-P260-P314-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
WGK Germany	WGK 3
Storage Class	11 - Combustible Solids
Hazard Classifications	Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1 STOT RE 2
REACH Registrations	Active

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M3606	Maropitant	147116-67-4	10MG	$143	2026-04-30	Buy
Cayman Chemical	34816	Maropitant ≥98%	147116-67-4	1mg	$39	2026-04-30	Buy
Cayman Chemical	34816	Maropitant ≥98%	147116-67-4	5mg	$106	2026-04-30	Buy
Cayman Chemical	34816	Maropitant ≥98%	147116-67-4	10mg	$193	2026-04-30	Buy
Cayman Chemical	34816	Maropitant ≥98%	147116-67-4	25mg	$434	2026-04-30	Buy

Product number	Packaging	Price	Buy
M3606	10MG	$143	Buy
34816	1mg	$39	Buy
34816	5mg	$106	Buy
34816	10mg	$193	Buy
34816	25mg	$434	Buy

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Chemical Properties, Uses, Production

Uses

Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.

Biological Activity

Maropitant is a neurokinin-1 receptor (NK-1R) antagonist with in vivo antiemetic efficacy.

in vivo

Treatment with 1 mg/kg Maropitant citrate, significantly reduces the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreases MAC by 16%. In contrast, epidural administration of either saline or Maropitant does not change the MAC (2.17% and 1.92 %, respectively).

IC 50

NK1

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine synthesis

Synthesis of (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine from Benzene, 2-(bromomethyl)-4-(1,1-dimethylethyl)-1-methoxy- and 1-Azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-, (2S,3S)-

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Preparation Products And Raw materials

Raw materials

1-Azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-, (2S,3S)- Benzene, 2-(bromomethyl)-4-(1,1-dimethylethyl)-1-methoxy-

Preparation Products

Maropitant citrate hydrate

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Suppliers

Global Suppliers ( 132)

Supplier	Tel	Email	Country	ProdList	Advantage
Tianjin Maitian Technology Co., Ltd	19102267946	motitech@126.com	China	96	58
Hubei widely chemical technology Co., Ltd.	027-83991130 18627774460	1718093273@QQ.COM	China	1617	58
Shanghai Mixiu Chemical Co., Ltd.	18101936766	eileen@shmychem.com	China	349	55
Tianjin Keluo Pharmaceutical Technology Co. LTD	022-23869539 18920052327	281258989@qq.com	China	65	58
Jinan Hongkangda Chemical Co., Ltd	0531-88901705 18753193522	810353473@qq.com	China	156	58
Henan Yinuokai New Materials Co., Ltd	18836288690 18836288690	3810041989@qq.com	China	1101	58
Chemvon Biotechnology Co., Ltd	021-50790412	info@chemvon.com	China	371	57
ZHIWE CHEMTECH CO LTD	021-20221225 13917446399	zwchem@163.com	China	522	61
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60

Supplier	Advantage
Tianjin Maitian Technology Co., Ltd	58
Hubei widely chemical technology Co., Ltd.	58
Shanghai Mixiu Chemical Co., Ltd.	55
Tianjin Keluo Pharmaceutical Technology Co. LTD	58
Jinan Hongkangda Chemical Co., Ltd	58
Henan Yinuokai New Materials Co., Ltd	58
Chemvon Biotechnology Co., Ltd	57
ZHIWE CHEMTECH CO LTD	61
Chembest Research Laboratories Limited	61
Chemsky (shanghai) International Co.,Ltd	60

View Latest Price from (2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	Maropitant 147116-67-4		1kg	99%	20ton	Jinan Jianfeng Chemical Co., Ltd
2026-05-11	Maropitant 147116-67-4	$43.00-118.00		99.91%	10g	TargetMol Chemicals Inc.
2026-03-20	2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine 147116-67-4	$9.90	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

Maropitant
147116-67-4
$0.00
99%
Jinan Jianfeng Chemical Co., Ltd

Maropitant
147116-67-4
$43.00-118.00
99.91%
TargetMol Chemicals Inc.

2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine
147116-67-4
$9.90
99%
Hebei Chuanghai Biotechnology Co., Ltd

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine Spectrum

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine(147116-67-4)¹HNMR

147116-67-4 ((2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine) Related Search:

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1of2

(2S,3S)-2-Benzhydryl-N-(5-tert-butyl-2-Methoxybenzyl)quinuclidin-3-aMine (2S-cis)-N-[[5-(1,1-DiMethylethyl)-2-Methoxyphenyl]Methyl]-2-(diphenylMethyl)-1-azabicyclo[2.2.2]octan-3-aMine (2S,3S)-2-(Diphenylmethyl)-N-[2-methoxy-5-(2-methyl-2-propanyl)benzyl]quinuclidin-3-amine 1-Azabicyclo[2.2.2]octan-3-amine, N-[[5-(1,1-dimethylethyl)-2-methoxyphenyl]methyl]-2-(diphenylmethyl)-, (2S,3S)- CJ-11972) Maropitant (CJ11,972 Maropitant-13C-d3Q: What is Maropitant-13C-d3 Q: What is the CAS Number of Maropitant-13C-d3 Maropitant base Horse's temple (2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine Maropitant intermediate 6 Pafolacianine Impurity 5 (2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxy-phenyl)methyl]quinuclidin-3-amine Maropitant, 10 mM in DMSO Maropitant Maropitan 147116-67-4 API Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals