Maropitant citrate hydrate
- CAS No.
- 359875-09-5
- Chemical Name:
- Maropitant citrate hydrate
- Synonyms
- 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID;ethyl[(1R)-1-[(2R)-oxolan-2-yl]-2-phenylethyl]amine;4-(4-fluorophenyl)-1-[4-(1,2,4-triazol-1-yl)butyl]-3,6-dihydro-2H-pyridine;(7S,8S)-7-benzhydryl-N-[(2-methoxy-5-tert-butyl-phenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine;ACIDUM CITRICUM ANHYDRICUM;Maropitant citrate hydrate;(2S,3S)-N-(5-tert-butyl-2-methoxybenzyl)-2-(diphenylmethyl)-...;(2S,3S)-2-benzhydryl-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine,2-hydroxypropane-1,2,3-tricarboxylic acid,hydrate;FEMA 2306;CT SUPPLEMENT
- CBNumber:
- CB4127749
- Molecular Formula:
- C38H48N2O8
- Molecular Weight:
- 660.81
- MDL Number:
- MFCD02098080
- MOL File:
- 359875-09-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| CT Supplement for microbiology | 77981 | 5amp | $151 |
| CT SUPPLEMENT 95.00% | CHM0992497 | 5MG | $502.05 |
| More product size | |||
| Melting point | 153-159 °C(lit.) |
|---|---|
| Flash point | 100 °C |
| storage temp. | 2-8°C |
| solubility | H2O: 1 M at 20 °C, clear, colorless |
| form | white to off-white crystalline powder |
| Water Solubility | Water: 3 mg/mL (4.42 mM) |
| Major Application |
agriculture environmental food and beverages || microbiology |
| InChIKey | XDZPFSKCXRGRIO-OHTRWSNQNA-N |
| SMILES | C(O)(C(=O)O)(CC(=O)O)CC(=O)O.C(C1C=CC=CC=1)(C1C=CC=CC=1)[C@@H]1N2CCC(CC2)[C@@H]1NCC1C=C(C(C)(C)C)C=CC=1OC |&1:26,33,r| |
| CAS DataBase Reference | 359875-09-5(CAS DataBase Reference) |
| FDA UNII | LXN6S3999X |
| UNSPSC Code | 41171614 |
| NACRES | NA.85 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS08,GHS09,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H400-H373-H318-H410 |
| Precautionary statements | P273-P391-P501-P273-P391-P501-P260-P314-P501-P280-P305+P351+P338-P310 |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | Xi,T |
| Risk Statements | 41-42/43-36/37/38-25 |
| Safety Statements | 26-39-45-36/37-22 |
| RIDADR | UN 3284 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | GE7350000 |
| F | 9 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 |
Maropitant citrate hydrate price More Price(2)
Maropitant citrate hydrate Chemical Properties,Uses,Production
Description
Maropitant citrate hydrate is a specific neurokinin-1 (NK-1) receptor antagonist that selectively inhibits the production of substance P, a mediator involved in signalling vomiting. Maropitant citrate was therefore originally used to treat vomiting in dogs and cats. Currently, it is also used as an adjunct to visceral analgesia in dogs and cats, and in other species such as horses and birds.
Uses
Anti-emetic.
Pharmacokinetics
The maximum, minimum, and average concentrations of maropitant achieved at steady state were 375.5 ± 200, 16.8 ± 7.7, and 73.5 ± 45.1 ng/ml, respectively. The terminal elimination half-life was 11.6 ± 1.4 hr, and the accumulation index was 1.3 ± 0.07. Heart rate decreased between Day 1 and Day 5 (p = .005), with three horses having heart rates of 20 beats per minute and atrioventricular block on Day 5. Pharmacokinetics of repeated maropitant administration suggests the drug could be considered for use in healthy horses.
Veterinary Drugs and Treatments
Maropitant citrate injectable solution is indicated for the prevention and treatment of acute vomiting in dogs; maropitant citrate tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs. Both are also used extra-label in cats.
Maropitant citrate hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| Hpets Biotech Company (Chongqing) Co.,ltd | +8613340353813 | info@hanpets.com | China | 26 | 58 |
| Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd | +86-02223869539 +86-15560057295 | trade.kilopharma@foxmail.com | China | 27 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 | sales2@runyanpharma.com | China | 302 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 421 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21599 | 55 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
Related articles
- Pharmacokinetic studies of maropitant citrate in different situation and clinical recommendations
- This article mainly summarizes the pharmacokinetic studies of maropitant citrate in different species under different administ....
- May 20，2025
View Lastest Price from Maropitant citrate hydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-23 | CT SUPPLEMENT
359875-09-5
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-01-23 | Maropitant Citrate
359875-09-5
|
US $0.00 / kg | 1kg | 99% | 100kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-09-25 | Maropitant citrate hydrate
359875-09-5
|
US $8.00-0.80 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- CT SUPPLEMENT
359875-09-5
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Maropitant Citrate
359875-09-5
- US $0.00 / kg
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Maropitant citrate hydrate
359875-09-5
- US $8.00-0.80 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
