PALDA
- CAS No.
- 136181-87-8
- Chemical Name:
- PALDA
- Synonyms
- N-PALMITOYL DOPAMINE;PALDA;N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]HEXADECANAMIDE;Hexadecanamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-
- CBNumber:
- CB0265319
- Molecular Formula:
- C24H41NO3
- Molecular Weight:
- 391.59
- MDL Number:
- MFCD08457915
- MOL File:
- 136181-87-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
PALDA price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10007697 | N-Palmitoyl Dopamine ≥98% | 136181-87-8 | 5mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 10007697 | N-Palmitoyl Dopamine ≥98% | 136181-87-8 | 10mg | $98 | 2026-04-30 | Buy |
| Cayman Chemical | 10007697 | N-Palmitoyl Dopamine ≥98% | 136181-87-8 | 50mg | $409 | 2026-04-30 | Buy |
| Cayman Chemical | 10007697 | N-Palmitoyl Dopamine ≥98% | 136181-87-8 | 100mg | $711 | 2026-04-30 | Buy |
| Usbiological | 256153 | PALDA Asreported | 136181-87-8 | 10mg | $353 | 2026-06-03 | Buy |
PALDA Chemical Properties, Uses, Production
Description
Several different fatty acyl dopamine analogs, such as N-
Uses
PALDA is an endogenous fatty acid dopamide.
Definition
ChEBI: N-palmitoyl dopamine is a fatty amide resulting from the formal condensation of the carboxy group of hexadecanoic acid with the amino group of dopamine. It is present as an endogenous compound in the mammalian brain. It is a monocarboxylic acid amide, a fatty amide, a member of catechols and a N-(fatty acyl)-dopamine. It is functionally related to a hexadecanoic acid and a dopamine.
Biological Activity
Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA; lowers EC 50 from ~ 90 to ~ 30 nM.
References
[1] SUSAN M. HUANG. Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain*[J]. The Journal of Biological Chemistry, 2001, 19 1: 42639-42644. DOI: 10.1074/jbc.m107351200
[2] CONSTANCE J CHU. N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.[J]. The Journal of Biological Chemistry, 2003, 278 16: 13633-13639. DOI: 10.1074/jbc.m211231200
[3] LUCIANO DE PETROCELLIS. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels[J]. British Journal of Pharmacology, 2009, 143 2: 251-256. DOI: 10.1038/sj.bjp.0705924
PALDA Preparation Products And Raw materials
Raw materials
Preparation Products
PALDA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Shanghai Guangyang Carrie Biotechnology Co., LTD | 13127532723 | lily@yhp-biomedicine.com | China | 800 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
