DMA
- CAS No.
- 188860-26-6
- Chemical Name:
- DMA
- Synonyms
- DMA, 10 mM in DMSO;2,5'-Bi-1H-benzimidazole, 2'-(3,4-dimethoxyphenyl)-5-(4-methyl-1-piperazinyl)-;2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole
- CBNumber:
- CB02666620
- Molecular Formula:
- C27H28N6O2
- Molecular Weight:
- 468.55
- MDL Number:
- MOL File:
- 188860-26-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
DMA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1309 | DMA 98.89% | 188860-26-6 | 5mg | $78 | 2026-06-04 | Buy |
| ChemScene | CS-1309 | DMA 98.89% | 188860-26-6 | 10mg | $117 | 2026-06-04 | Buy |
| ChemScene | CS-1309 | DMA 98.89% | 188860-26-6 | 25mg | $260 | 2026-06-04 | Buy |
| ChemScene | CS-1309 | DMA 98.89% | 188860-26-6 | 50mg | $468 | 2026-06-04 | Buy |
| ChemScene | CS-1309 | DMA 98.89% | 188860-26-6 | 100mg | $858 | 2026-06-04 | Buy |
DMA Chemical Properties, Uses, Production
Description
DMA is a fluorescent dye used for staining DNA.
Uses
DMA is a fluorescent compound (λex=340 nm, λem=478 nm).
Biological Activity
DMA is a fluorescent compound (λex=340 nm, λem=478 nm).
in vitro
The newly synthesized bisbenzimidazole derivatives DMA (6c) is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87 ) in comparison to Hoechst. In case of MCF7, the IC 50 is observed at 5.3 μM for DMA. The IC 50 determined in the case of HeLa is 3.4 μM for DMA .
target
IC50: 3.4 μM (HeLa cell), 5.3 μM (MCF7 cell)
References
[1] Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69. DOI:10.1016/j.ejmech.2010.11.046
DMA Preparation Products And Raw materials
Raw materials
Preparation Products
DMA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9780 | 55 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14571 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| Shanghai Zhen Li Biological Technology Co., Ltd | 021-16621358918; 18516310516;16621358918;13045646768 | zhenlipharma888@163.com | China | 19060 | 58 |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815688 13927872512 | 3007421951@qq.com | China | 9996 | 58 |
