4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide
- CAS No.
- 959-81-9
- Chemical Name:
- 4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide
- Synonyms
- Daspi;TRANS-4-[4-(DIMETHYLAMINO)STYRYL]-1-METHYLPYRIDINIUM IODIDE;D 288;DASPMI;4-DI-1-ASP;AURORA 18081;4-DI-1-ASP IODIDE;4-Di-1-ASP [DASPMI];40-dimethylamino-1-methylstilbazolium Iodide;4-Di-1-ASP (Mitochondrial Fluorescent Probe)
- CBNumber:
- CB0283755
- Molecular Formula:
- C16H19N2.I
- Molecular Weight:
- 366.24
- MDL Number:
- MFCD00031907
- MOL File:
- 959-81-9.mol
- MSDS File:
- SDS
| Melting point | 261–262℃ |
|---|---|
| solubility | Soluble in methanol, N,N-dimethylformamide |
| form | Solid |
| pka | 3.1(Temp: 25 °C; Solvent: Water) |
| color | Greenish purple solid;2 Purple solid; Red needles |
| Appearance | Solid Powder |
| λmax | 475 nm |
| Major Application | Electrochromic materials;glass;nonlinear optical (NLO) materials;photoconductors;thin films |
| Biological Applications | Detecting nucleic acids,prostate cancer; treating amyloidosis disorders,bacterial infection |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0181320 | 4-Di-1-ASP 99.95% | 959-81-9 | 200mg | $71 | 2026-06-04 | Buy |
| Matrix Scientific | 309326 | (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide | 959-81-9 | 100.00mg | $65 | 2026-05-19 | Buy |
| Matrix Scientific | 309326 | (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide | 959-81-9 | 250.00mg | $110 | 2026-05-19 | Buy |
| Matrix Scientific | 309326 | (E)-4-(4-(Dimethylamino)styryl)-1-methylpyridin-1-ium iodide | 959-81-9 | 1.00g | $285 | 2026-05-19 | Buy |
| ApexBio Technology | C8288 | 4-Di-1-ASP | 959-81-9 | 200mg | $59 | 2026-05-06 | Buy |
4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide Chemical Properties,Uses,Production
Description
4-(4-(dimethylamino)styryl)-n-methylpyridinium iodide is utilized in the biomedical industry as a fluorescent probe that specifically stains mitochondria. It is commonly used to study mitochondrial function, localization, and dynamics in various cell types. Additionally, this compound aids in investigating diseases associated with mitochondrial dysfunction such as neurodegenerative disorders and cancer.
Uses
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λex /λem = 475/606 nm) [1][2].
Definition
ChEBI: 4-[4-(dimethylamino)styryl]-N-methylpyridinium iodide is an organic iodide salt consisting of pyridinium iodide having a methyl substituent at the 1-position and a 4-dimethylaminostyryl substituent at the 4-position. It has a role as a fluorochrome. It is an organic iodide salt and a pyridinium salt. It contains a 4-[4-(dimethylamino)styryl]-N-methylpyridinium.
References
[1] Lilia Y Kucheryavykh, et al. Visualization of implanted GL261 glioma cells in living mouse brain slices using fluorescent 4-(4-(dimethylamino)-styryl)-N-methylpyridinium iodide (ASP+). Biotechniques. 2012 Nov;53(5):305-9. DOI:10.2144/000113940
[2] Jensen J H Wong, et al. Simultaneous High-Throughput Conformational and Colloidal Stability Screening Using a Fluorescent Molecular Rotor Dye, 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide (DASPMI). J Biomol Screen. 2016 Sep;21(8):842-50. DOI:10.1177/1087057116646553
Excitation / Emission Maximum
340 nm/488 nm
4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide Preparation Products And Raw materials
Raw materials
Preparation Products
4-(4-(Dimethylamino)styryl)-N-methylpyridinium iodide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9385 | 58 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24636 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Zhengzhou anmousse chemical products co. LTD | 15981811963 18737195735 | 483339295@qq.com | China | 7884 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 13393710386 | 3941078109@qq.com | China | 9834 | 58 |
| Sci-Sun Technology CO.,Ltd | 18252089365 | Krain_kerun@163.com | China | 2853 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5987 | 58 |
