Di-8-anepps
- CAS No.
- 157134-53-7
- Chemical Name:
- Di-8-anepps
- Synonyms
- Jpw 1153;Di-8-anepps;Di-8-ANEPPS *CAS#: 157134-53-7*;Di-8-ANEPPS Membrane Potential Probe;4-(2-[6-(DIOCTYLAMINO)-2-NAPHTHALENYL]ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM INNER SALT;3-(4-(2-(6-(Dioctylamino)naphthalen-2-yl)vinyl)pyridin-1-ium-1-yl)propane-1-sulfonate;Pyridinium, 4-[2-[6-(dioctylamino)-2-naphthalenyl]ethenyl]-1-(3-sulfopropyl)-, inner salt;4-amino-1-((2R,3R,4R,5S)-4-azido-5-(hydroxymethyl)-3-(2-(trifluoromethoxy)ethoxy)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
- CBNumber:
- CB0670762
- Molecular Formula:
- C36H52N2O3S
- Molecular Weight:
- 592.87
- MDL Number:
- MFCD03453608
- MOL File:
- 157134-53-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >200℃ |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | powder |
| color | orange to red |
| Appearance | Orange solid |
| ex/em | 468/633 nm (artificial membrane) |
| λmax | 498 nm |
| ε(extinction coefficient) | ≥37 at 495-501 nm in methanol |
| Major Application |
diagnostic assay manufacturing hematology histology |
| Biological Applications | Measuring membrane potential |
| InChIKey | IXFSUSNUALIXLU-UHFFFAOYSA-N |
| SMILES | CCCCCCCCN(CCCCCCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1 |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Di-8-anepps price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D1065 | 4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt ≥95% (HPLC), solid | 157134-53-7 | 5mg | $561 | 2026-04-30 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 500μg | $54 | 2026-04-30 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 1mg | $102 | 2026-04-30 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 5mg | $369 | 2026-04-30 | Buy |
| ChemScene | CS-7775 | Di-8-ANEPPS 99.46% | 157134-53-7 | 1mg | $95 | 2026-06-04 | Buy |
Di-8-anepps Chemical Properties,Uses,Production
Description
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Chemical Properties
Appearance: Orange-red solid
ex/em: 468/633 nm (artificial membrane)
Extinction coefficient (ε): 44,000 Lmol1cm1 (methanol)
Uses
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Uses
Di-8-ANEPPS is a fast-responding membrane potential dye. It is more suitable for long-term membrane potential studies than di-4-ANEPPS (sc-214872) because of its better retention in the outer leaflet of plasma membranes. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses.Dyes and metabolites.
References
[1] GORAZD PUCIHAR Damijan M Tadej Kotnik. Measuring the induced membrane voltage with Di-8-ANEPPS.[J]. Jove-Journal of Visualized Experiments, 2009, 33. DOI: 10.3791/1659
Abs/Em Maxima
499/708 nm
Excitation / Emission Maximum
467 nm/631 nm
Di-8-anepps Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14571 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 3927209986@qq.com | China | 9997 | 55 |
View Lastest Price from Di-8-anepps manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | Di-8-ANEPPS
157134-53-7
|
$99.00 | 99.17% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-07 | DI-8-ANEPPS
157134-53-7
|
100mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Di-8-ANEPPS
157134-53-7
- $99.00
- 99.17%
- TargetMol Chemicals Inc.
-
- DI-8-ANEPPS
157134-53-7
- $0.00
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
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