DI-8-ANEPPS
- CAS No.
- 157134-53-7
- Chemical Name:
- DI-8-ANEPPS
- Synonyms
- Jpw 1153;DI-8-ANEPPS;Di-8-ANEPPS *CAS#: 157134-53-7*;4-(2-[6-(DIOCTYLAMINO)-2-NAPHTHALENYL]ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM INNER SALT;3-(4-(2-(6-(Dioctylamino)naphthalen-2-yl)vinyl)pyridin-1-ium-1-yl)propane-1-sulfonate;Pyridinium, 4-[2-[6-(dioctylamino)-2-naphthalenyl]ethenyl]-1-(3-sulfopropyl)-, inner salt
- CBNumber:
- CB0670762
- Molecular Formula:
- C36H52N2O3S
- Molecular Weight:
- 592.87
- MDL Number:
- MFCD03453608
- MOL File:
- 157134-53-7.mol
| Product description | Number | Pack Size | Price |
| 4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt ≥95% (HPLC), solid | D1065 | 5mg | $538 |
| Di-8-ANEPPS ≥98% | 19541 | 500μg | $49 |
| Di-8-ANEPPS ≥98% | 19541 | 1mg | $92 |
| Di-8-ANEPPS ≥98% | 19541 | 5mg | $335 |
| Di-8-ANEPPS | D416428 | 10mg | $380 |
| More product size | |||
| Melting point | >200℃ |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| form | powder |
| color | orange to red |
| Appearance | Orange solid |
| ex/em | 468/633 nm (artificial membrane) |
| ε(extinction coefficient) | ≥37 at 495-501 nm in methanol |
| λmax | 498 nm |
| Major Application |
diagnostic assay manufacturing hematology histology |
| Biological Applications | Measuring membrane potential |
| InChIKey | IXFSUSNUALIXLU-UHFFFAOYSA-N |
| SMILES | CCCCCCCCN(CCCCCCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1 |
| UNSPSC Code | 12171500 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
DI-8-ANEPPS price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D1065 | 4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt ≥95% (HPLC), solid | 157134-53-7 | 5mg | $538 | 2025-07-31 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 500μg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 1mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 19541 | Di-8-ANEPPS ≥98% | 157134-53-7 | 5mg | $335 | 2024-03-01 | Buy |
| TRC | D416428 | Di-8-ANEPPS | 157134-53-7 | 10mg | $380 | 2021-12-16 | Buy |
DI-8-ANEPPS Chemical Properties,Uses,Production
Description
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Chemical Properties
Appearance: Orange-red solid
ex/em: 468/633 nm (artificial membrane)
Extinction coefficient (ε): 44,000 Lmol1cm1 (methanol)
Uses
Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker.
Uses
Di-8-ANEPPS is a fast-responding membrane potential dye. It is more suitable for long-term membrane potential studies than di-4-ANEPPS (sc-214872) because of its better retention in the outer leaflet of plasma membranes. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses.Dyes and metabolites.
References
[1] GORAZD PUCIHAR Damijan M Tadej Kotnik. Measuring the induced membrane voltage with Di-8-ANEPPS.[J]. Jove-Journal of Visualized Experiments, 2009, 33. DOI: 10.3791/1659
Abs/Em Maxima
499/708 nm
Excitation / Emission Maximum
467 nm/631 nm
DI-8-ANEPPS Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9258 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32469 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Xi'an Kaixin Biotechnology Co., Ltd | 029-68881181 13619217766 | 3495811982@qq.com | China | 2806 | 58 |
| Beijing Ouhe Technology Co., Ltd | 010-82967028 13522913783 | 2355560935@qq.com | China | 11776 | 60 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 25891 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Synchem OHG | +49 5662 408730 | info@synchem.de | Germany | 4705 | 70 |
View Lastest Price from DI-8-ANEPPS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-03 | Di-8-ANEPPS
157134-53-7
|
US $99.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2025-06-07 | DI-8-ANEPPS
157134-53-7
|
US $0.00 / mg | 100mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Di-8-ANEPPS
157134-53-7
- US $99.00 / mg
- TargetMol Chemicals Inc.
-
- DI-8-ANEPPS
157134-53-7
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
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