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Flavin adenine dinucleotide

CAS No.
146-14-5
Chemical Name:
Flavin adenine dinucleotide
Synonyms
DISODIUM FLAVINE ADENINE DINUCLEOTIDE;Fademin;flavitan;flavinat;Flavinin;Wakadenin;NSC 112207;FAD Powder;Flavine Adenine;5'-ester with adenosine
CBNumber:
CB0294159
Molecular Formula:
C27H33N9O15P2
Molecular Weight:
785.55
MDL Number:
MFCD00041835
MOL File:
146-14-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-07 16:58:08

Flavin adenine dinucleotide Properties

Density 2.08±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Methanol (Slightly, Heated), Water (Slightly)
pka 1.13±0.50(Predicted)
form powder
color orange
Merck 4091
Stability Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions VISCOSITY CONTROLLING
InChIKey VWWQXMAJTJZDQX-ZGGJIJKNNA-N
CAS DataBase Reference 146-14-5
EWG's Food Scores 1
FDA UNII ZC44YTI8KK
EPA Substance Registry System Riboflavin 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with adenosine (146-14-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
Safety Statements  24/25
WGK Germany  3
RTECS  AU7470000
8-10-21
TSCA  TSCA listed
HS Code  29349990

Flavin adenine dinucleotide price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 012061 Flavine Adenine Dinucleotide Disodium Salt 146-14-5 25mg $496 2026-06-03 Buy
Biosynth NF182245 Flavin adenine dinucleotide 146-14-5 25mg $249.75 2026-06-04 Buy
Biosynth NF182245 Flavin adenine dinucleotide 146-14-5 50mg $416.5 2026-06-04 Buy
Biosynth NF182245 Flavin adenine dinucleotide 146-14-5 100mg $665 2026-06-04 Buy
Biosynth NF182245 Flavin adenine dinucleotide 146-14-5 250mg $1247.5 2026-06-04 Buy
Product number Packaging Price Buy
012061 25mg $496 Buy
NF182245 25mg $249.75 Buy
NF182245 50mg $416.5 Buy
NF182245 100mg $665 Buy
NF182245 250mg $1247.5 Buy

Flavin adenine dinucleotide Chemical Properties, Uses, Production

Description

Flavin adenine dinucleotide (FAD) is a cofactor for cytochrome-b5 reductase, the enzyme that maintains hemoglobin in its functional reduced state, and for glutathione reductase. This enzyme also protects erythrocytes from oxidative damage. FAD is a redox cofactor of several essential reactions in metabolism. This cofactor exists in two redox states, with FAD and FADH2 being the oxidized and reduced forms, respectively. FAD is formed of a riboflavin moiety (vitamin B2) coupled to a phosphate group of an ADP molecule. The reaction starts with the conversion of riboflavin into flavin mononucleotide catalyzed by riboflavin kinase. Flavin mononucleotide is subsequently transformed into FAD by adding an AMP moiety from ATP catalyzed by FAD-synthase. Therefore, FAD availability is tightly dependent on vitamin B2 and energy metabolism[1].

References

[1] Schnekenburger, M. and M. Diederich. “Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches.”Epigenetic Cancer Therapy (2015): 393-425.

Chemical Properties

solid

Uses

Labelled Flavine Adenine xidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase

Uses

The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.

Definition

An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5′-position.

Purification Methods

Small quantities of FAD are purified by paper chromatography using tert-butyl alcohol/water, cutting out the main spot and eluting with water. Larger amounts can be precipitated from water as the uranyl complex by adding a slight excess of uranyl acetate to a solution at pH 6.0, dropwise and with gentle stirring. The solution is set aside overnight in the cold, and the precipitate is centrifuged off, washed with small portions of cold EtOH, then with cold peroxide-free diethyl ether. It is dried in the dark under vacuum over P2O5 at 50-60o. The uranyl complex is suspended in water, and, after adding sufficient 0.01M NaOH to adjust the pH to 7, the precipitate of uranyl hydroxide is removed by centrifugation [Huennekens & Felton Methods Enzymol 3 954 1957]. It can also be crystallised from water. It should be kept in the dark. More recently it was purified by elution from a DEAE-cellulose (Whatman DE 23) column with 0.1M phosphate buffer pH 7, and the purity was checked by TLC. [Holt & Cotton, J Am Chem Soc 109 1841 1987, Beilstein 26 III/IV 3632.]

Flavin adenine dinucleotide Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 168)
Supplier Tel Email Country ProdList Advantage
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Xianning Shen Lan Biomedical Research and Development Co., Ltd. 18171815831 1341138380@qq.com China 4573 58
Shanghai ZymeTree Biotech Co.,Ltd. 15300487802 jlin@microbiosyn.com China 223 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Syncozymes (Shanghai) Co.,Ltd. 021-68187180 13681683526 lchen@syncozymes.com China 412 55

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View Latest Price from Flavin adenine dinucleotide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Flavin adenine dinucleotide pictures 2026-09-14 Flavin adenine dinucleotide
146-14-5
1g 0.95 10000 g Nanjing pathgene biotech co .,ltd
Flavin adenine dinucleotide pictures 2026-07-15 Flavin adenine dinucleotide
146-14-5
$37.00-88.00 99.98% 10g TargetMol Chemicals Inc.
FLAVIN ADENINE DINUCLEOTIDE pictures 2026-03-20 FLAVIN ADENINE DINUCLEOTIDE
146-14-5
$10.00 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd

Flavin adenine dinucleotide Spectrum

adenine-flavindinucleotide adenine-flavinedinucleotide adenine-riboflavindinuceotide flavitan isoalloxazine-adeninedinucleotide riboflavin5’-(trihydrogendiphosphate),5’.fwdarw.5’-esterwithadenosine riboflavin5’-(trihydrogendiphosphate),5’-5’-esterwithadenosine riboflavin-adeninedinucleotide riboflavine-adeninedinucleotide FLAVIN ADENINE DINUCLEOTIDE Flavine-adenine dinucleotide DISODIUM FLAVINE ADENINE DINUCLEOTIDE adenine-riboflavindinucleotide adenosine5’-(trihydrogenpyrophosphate),5’-5’-esterwithriboflavine flavinadenindinucleotide flavinadeninedinucleotidedisodium flavinat flavineadeninedinucleotide,disodiumflavineadeninedinucleotide flavineadenosinediphosphate FLAVIN ADENINE DINUCLEOTIDE 2NA (FAD) Riboflavine 5'-adenosine diphosphate Adenine-riboflavine dinucleotide Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with riboflavine (8CI) Fademin NSC 112207 Riboflavin 5'-adenosine diphosphate Riboflavine, 5'-ester with adenosine 5'-diphosphate (8CI) FLAVINE ADENINE DINUCLEOTIDE SODIUM SALT extrapure flavin adenosine dinucleotide Riboflavin 5-(trihydrogen diphosphate), P?5-ester with adenosine Riboflavin 5'-(trihydrogen diphosphate) 5'-ester with adenosine Riboflavin5'-(trihydrogen diphosphate), P'® Flavinin Wakadenin Flavine-adenine dinucleotide,96% Flavine Adenine Flavin adenine dinucleotide ,95% FLAVIN ADENINE DINUCLEOTIDE USP/EP/BP flavine Adenine Dinucleotide-13C5 Ammonium SaltQ: What is flavine Adenine Dinucleotide-13C5 Ammonium Salt Q: What is the CAS Number of flavine Adenine Dinucleotide-13C5 Ammonium Salt Flavine Adenine Dinucleotide Sodium Salt (FAD) extrapure, 95% FAD Powder (((2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)(((((2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl)oxy)(hydroxy)phosphoryl)oxy)phosphinic acid Flavine adenine dinucleotide,FAD Riboflavin5'-(trihydrogen diphosphate), P'?5'-ester with adenosine Active vitamin B2 disodium salt Flavine Adenine Dinucleotide(FAD Free) 146-14-5 C2213C5H31N9Na2O15P2 C27H31N9O15P2Na2 C27H33N9O15P2 C27N33N9O15P2 Metabolic Pathways Metabolomics Electron Transport and Cellular Respiration Cofactors and Substrates BioChemical Biochemistry