JP 1302 2HCl
- CAS No.
- 1259314-65-2
- Chemical Name:
- JP 1302 2HCl
- Synonyms
- JP-1302 HCl;JP 1302 2HCl;JP-1302 (hydrochloride);JP1302 dihydrochloride, 10 mM in DMSO;JP1302 dihydrochloride, alpha2C antagonist;N-(4-(4-Methylpiperazin-1-yl)phenyl)acridin-9-amine dihydrochloride;Inhibitor,JP 1302,JP-1302,JP1302 dihydrochloride,inhibit,JP1302,Beta Receptor,Adrenergic Receptor,JP-1302 dihydrochloride
- CBNumber:
- CB03038505
- Molecular Formula:
- C24H25ClN4
- Molecular Weight:
- 404.94
- MDL Number:
- MOL File:
- 1259314-65-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
JP 1302 2HCl price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 255566 | JP 1302 dihydrochloride Asreported | 1259314-65-2 | 10mg | $480 | 2026-06-03 | Buy |
| Usbiological | 255566 | JP 1302 dihydrochloride Asreported | 1259314-65-2 | 50mg | $1338 | 2026-06-03 | Buy |
| Biosynth | JAC31465 | JP 1302 dihydrochloride | 1259314-65-2 | 50mg | $1117.5 | 2026-06-04 | Buy |
| Biosynth | JAC31465 | JP 1302 dihydrochloride | 1259314-65-2 | 100mg | $1555 | 2026-06-04 | Buy |
| ChemScene | CS-0025304 | JP1302 dihydrochloride 99.94% | 1259314-65-2 | 5mg | $119 | 2026-06-04 | Buy |
JP 1302 2HCl Chemical Properties, Uses, Production
Uses
JP 1302 Dihydrochloride is an α2-adrenoceptor blocker and can be used for the treatment or prevention of nephropathy.
in vivo
JP1302 (1-10 μmol/kg) decreases immobility time in the FST to a level similar to that seen with 10-30 μmol/kg of the antidepressant Desipramine (HY-B1272A)[1].
JP1302 (5 μmol/kg, once) is capable of complete reversal of the impairment in PPI induced in Sprague-Dawley rats by the psychotomimetic NMDA receptor antagonist, phencyclidine and similar results are found in Wistar rats[1].
JP1302 (3 mg/kg, IV, once) significantly ameliorates renal dysfunction[3].
| Animal Model: | Male Sprague Dawley rats (8 weeks old)[3] |
| Dosage: | 3 mg/kg |
| Administration: | IV, pre-treatment: administered 5 min before the induction of ischemia, post-treatment: injected 45 min after the initiation of reperfusion |
| Result: | Significantly ameliorated renal dysfunction in the rats at 24 h after reperfusion. post-ischemic administration of JP-1302 significantly ameliorated renal dysfunction, histological damage and reduced apoptotic cells and pro-inflammatory cytokine mRNA expression. |
IC 50
human α2C-adrenoceptor: 28±2 nM (Ki); human α2B-adrenoceptor: 1470±130 nM (Ki); human α2A-adrenoceptor: 3150±50 nM (Ki); rodent α2D-adrenoceptor: 1700±200 nM (Ki)
storage
Store at -20°C
JP 1302 2HCl Preparation Products And Raw materials
Raw materials
Preparation Products
JP 1302 2HCl Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2774 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 989 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9778 | 55 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Beijing LAL Pharmaceutical Co., Ltd. | 010-010-62452898 13581984929 | jlzhang929@163.com | China | 91 | 58 |
| Chengdu Saint - Kay Biotechnology Co., Ltd. | 028-85157043 15882256948 | 676046971@qq.com | China | 4183 | 58 |
View Latest Price from JP 1302 2HCl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | JP1302 dihydrochloride
1259314-65-2
|
$88.00-247.00 | 99.61% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-15 | JP1302 dihydrochloride
1259314-65-2
|
$88.00-247.00 | 99.61% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-18 | JP 1302 2HCl
1259314-65-2
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd |
-
- JP1302 dihydrochloride
1259314-65-2
- $88.00-247.00
- 99.61%
- TargetMol Chemicals Inc.
-
- JP1302 dihydrochloride
1259314-65-2
- $88.00-247.00
- 99.61%
- TargetMol Chemicals Inc.
-
- JP 1302 2HCl
1259314-65-2
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
