Hecogenin
- CAS No.
- 467-55-0
- Chemical Name:
- Hecogenin
- Synonyms
- Hocogenin;(25R);Hecoginin;HECOGENIN;Hecogrnin;Hecogenin (>12-Oxotigogenin;Hecogenin (>80%);HECOGENIN 98.0% BY HPLC;5α-Spirostan-3β-ol-12-one
- CBNumber:
- CB0308063
- Molecular Formula:
- C27H42O4
- Molecular Weight:
- 430.62
- MDL Number:
- MFCD00067285
- MOL File:
- 467-55-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 268°C |
|---|---|
| alpha | 7.2 º (c=0.8 g/100ml, CHCl3) |
| Boiling point | 464.85°C (rough estimate) |
| Density | 1.0040 (rough estimate) |
| refractive index | 1.4840 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 15.10±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Merck | 14,4622 |
| CAS DataBase Reference | 467-55-0(CAS DataBase Reference) |
| FDA UNII | 3XP44JJ79F |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H312-H315-H319-H371-H373-H317-H351-H335-H400-H290 | |||||||||
| Precautionary statements | P501-P273-P272-P260-P270-P202-P234-P201-P271-P264-P280-P390-P391-P337+P313-P305+P351+P338-P308+P311-P362+P364-P333+P313-P301+P310+P330-P302+P352+P312-P304+P340+P312-P403+P233-P406-P405 | |||||||||
| HS Code | 2937.29.9095 | |||||||||
| NFPA 704 |
|
Hecogenin price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H0003 | Hecogenin >80.0%(GC) | 467-55-0 | 1g | $117 | 2026-04-30 | Buy |
| TCI Chemical | H0003 | Hecogenin >80.0%(GC) | 467-55-0 | 100mg | $30 | 2026-04-30 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 100mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 250mg | $107 | 2026-04-30 | Buy |
| Cayman Chemical | 21372 | Hecogenin ≥80% | 467-55-0 | 1g | $213 | 2026-04-30 | Buy |
Hecogenin Chemical Properties,Uses,Production
Uses
antiinflammatory
Uses
Hecogenin, is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Definition
ChEBI: Hecogenin is a triterpenoid.
in vivo
Hecogenin (3.1-90 mg/kg; oral administration; for 15 hours; male Swiss mice) acutely administered, before ethanol, exhibits a potent gastroprotective effect. The Hecogenin pretreatment normalizes GSH levels and significantly reduces lipid peroxidation and nitrite levels in the stomach, as evaluated by the ethanol-induced gastric lesion model. Hecogenin also decreases MPO release and significantly protects the gastric mucosa[1].
| Animal Model: | Male Swiss mice (20-30 g) with ethanol[1] |
| Dosage: | 3.1 mg/kg, 7.5 mg/kg, 15 mg/kg, 30 mg/kg, 60 mg/kg and 90 mg/kg |
| Administration: | Oral administration; for 15 hours |
| Result: | Normalized GSH levels and significantly reduced lipid peroxidation and nitrite levels in the stomach, as evaluated by the ethanol-induced gastric lesion model. Decreased MPO release and significantly protected the gastric mucosa. |
Purification Methods
The saponin (~35 mg) in EtOAc is chromatographed on Al2O3 and eluted with *C6H6/Et2O, and the residue on evaporation is recrystallised from Me2CO. [Mazur et al. J Am Chem Soc 82 5889 1960, Marker et al. J Am Chem Soc 69 2167 1947, Beilstein 19 III/IV 2581.]
Hecogenin Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| RYSS TECH LTD | 400-188-0725 +86 21 34310725 13611771617 | China | 1999 | 57 | |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 |
View Lastest Price from Hecogenin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | Hecogenin
467-55-0
|
$1.00-2.00 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-04-22 | Hecogenin
467-55-0
|
$42.00-89.00 | 99.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-02-24 | Hecogenin
467-55-0
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
