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Ginsenoside Rh2

Ginsenoside Rh2 structure

CAS No.: 78214-33-2

Chemical Name:: Ginsenoside Rh2

Synonyms: Rh2;20(S)-Rh2;GINSENOSIDE RH2;Ginsenoside Rh2-RM;Ginsenoside Rh2(P);GINSENOSIDE Rh2(SH);Ginsenoside Rh2(AS);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2

CBNumber:: CB3728899

Molecular Formula:: C36H62O8

Molecular Weight:: 622.88

MDL Number:: MFCD00800712

MOL File:: 78214-33-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-27 17:00:41

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Ginsenoside Rh2 Properties

Melting point	139-144 °C
Boiling point	726.4±60.0 °C(Predicted)
Density	1.19±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
pka	12.91±0.70(Predicted)
form	Solid
color	White
Major Application	food and beverages
InChIKey	CKUVNOCSBYYHIS-IRFFNABBSA-N
SMILES	C\C(C)=C/CC[C@](C)(O)[C@H]1CC[C@]2(C)[C@@H]1[C@H](O)C[C@@H]3[C@@]4(C)CC[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C(C)(C)[C@@H]4CC[C@@]23C
LogP	5.620 (est)
CAS DataBase Reference	78214-33-2(CAS DataBase Reference)
FDA UNII	0JU44A5KWG
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

Hazard Codes

Risk Statements

Safety Statements

24/25

WGK Germany

RTECS

LZ5776539

HS Code

29389090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

Ginsenoside Rh2 price More Price(64)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	73658	Ginsenoside Rh2 analytical standard	78214-33-2	10mg	$774	2026-04-30	Buy
Cayman Chemical	23390	20(S)-Ginsenoside Rh2 ≥98%	78214-33-2	1mg	$54	2026-04-30	Buy
Cayman Chemical	23390	20(S)-Ginsenoside Rh2 ≥98%	78214-33-2	5mg	$209	2026-04-30	Buy
Cayman Chemical	23390	20(S)-Ginsenoside Rh2 ≥98%	78214-33-2	10mg	$315	2026-04-30	Buy
Cayman Chemical	23390	20(S)-Ginsenoside Rh2 ≥98%	78214-33-2	25mg	$717	2026-04-30	Buy

Product number	Packaging	Price	Buy
73658	10mg	$774	Buy
23390	1mg	$54	Buy
23390	5mg	$209	Buy
23390	10mg	$315	Buy
23390	25mg	$717	Buy

Ginsenoside Rh2 Chemical Properties,Uses,Production

Description

Ginsenoside Rh₂ is a steroid glycoside found in plants of the genus Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC₅₀ = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner. In vivo, ginsenoside Rh₂ decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh₂ also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.

Chemical Properties

White solid

Uses

20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.

Definition

ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.

Biological Activity

Ginsenoside-Rh2, a plant glycosidewith a dammarane skeleton, has been shown to induce apoptosis in a caspase 3,8-dependent manner or the activation of cyclinA-Cdk2 by caspase 3-mediated cleavage of p21(WAF1/CIP1). Also, ginsenoside-Rh2 was shown to inhibit proliferation by inducing the protein expression of p21 and reducing the protein levels of cyclin D, which resulted in the downregulation of cyclin/Cdk complex kinase activity, a reduction in phosphorylation of pRb and the inhibition of E2F release or modulation of MAP kinases in various cancer cells[1].

References

[1] EUN-KYUNG PARK. Antiallergic activity of ginsenoside Rh2.[J]. Biological & pharmaceutical bulletin, 2003, 26 11: 1581-1584. DOI: 10.1248/bpb.26.1581
[2] EUN-KYUNG PARK. Ginsenoside Rh2 reduces ischemic brain injury in rats.[J]. Biological & pharmaceutical bulletin, 2004, 27 3: 433-436. DOI: 10.1248/bpb.27.433
[3] Y KIKUCHI. Inhibition of human ovarian cancer cell proliferation in vitro by ginsenoside Rh2 and adjuvant effects to cisplatin in vivo.[J]. Anti-Cancer Drugs, 1991, 2 1: 63-67. DOI: 10.1097/00001813-199102000-00009
[4] XI-PING TANG. Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells.[J]. World Journal of Gastroenterology, 2013, 19 10: 1582-1592. DOI: 10.3748/wjg.v19.i10.1582
[5] JIA WANG. Ginsenoside Rh2 alleviates tumor-associated depression in a mouse model of colorectal carcinoma.[J]. American journal of translational research, 2016, 8 5: 2189-2195.

Ginsenoside Rh2 Preparation Products And Raw materials

Raw materials

Preparation Products

Ginsenoside Rh2 Suppliers

Global( 351)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Kebele Pharmaceutical R&D Co., Ltd	13119135307	3866620171@qq.com	China	2659	58
Chengdu Biopurify Phytochemicals Ltd.	+86-028-82633397 18982077548	cwb1@biopurify.cn	China	2376	60
Weifang Huazhi Biological Technology Co., Ltd.	17388075642 13815430202	sale02@cqherb.com	China	50	58
Shanghai Yihe Biological Technology Co., Ltd.	021-68882955 17721395025	2423903095@qq.com	China	4999	58
Bontac Bio-engineering (Shenzhen) Co., Ltd.	+86-0755-27212902 18025386762	marketing@bontac-bio.com	China	25	60
Shanghai Winherb Medical Technology Co., Ltd.	17301719108 13341702378	winherb@126.com	China	1245	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	5996	61
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
China DongFan Chemical Co.,LTD	86-0571-85151182		China	5681	66

Supplier	Advantage
Shaanxi Kebele Pharmaceutical R&D Co., Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	60
Weifang Huazhi Biological Technology Co., Ltd.	58
Shanghai Yihe Biological Technology Co., Ltd.	58
Bontac Bio-engineering (Shenzhen) Co., Ltd.	60
Shanghai Winherb Medical Technology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Chembest Research Laboratories Limited	61
Adamas Reagent, Ltd.	59
China DongFan Chemical Co.,LTD	66

Antitumor activity of Ginsenoside Rh2
Modern medical studies report that Ginsenoside Rh2 not only displays anti-proliferation, anti-invasion, anti-metastasis, induc....
Apr 9,2026

Unraveling the Anticancer Mechanisms of Ginsenoside Rh2
It has been demonstrated that GRh2 exhibits pharmacological activity against multiple cancers and can improve immune function.....
Aug 14,2024

View Lastest Price from Ginsenoside Rh2 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	Ginsenoside Rh2 78214-33-2		1g	≥98% HPLC	1000kg	Changsha Staherb Natural Ingredients Co., Ltd.
2026-08-25	Ginsenoside Rh2 78214-33-2	$100.00-1000.00	1KG	0.99	20 tons	Zibo Hangyu Biotechnology Development Co., Ltd
2026-08-09	Ginsenoside Rh2 78214-33-2			99	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.

Ginsenoside Rh2
78214-33-2
$0.00
≥98% HPLC
Changsha Staherb Natural Ingredients Co., Ltd.

Ginsenoside Rh2
78214-33-2
$100.00-1000.00
0.99
Zibo Hangyu Biotechnology Development Co., Ltd

Ginsenoside Rh2
78214-33-2
99
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Ginsenoside Rh2 Spectrum

Ginsenoside Rh2(78214-33-2)MS Ginsenoside Rh2(78214-33-2)¹HNMR

78214-33-2(Ginsenoside Rh2)Related Search:

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Ginsenoside Rh1 Ginsenoside Rb3 GINSENOSIDE F2

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b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside Ginsenoside Rh2, 20(S)- (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside GINSENOSIDE RH2 dihydroxydammar-24-en-3-yl β-D-Glucopyranoside, (3β,12β)-12,20- R-form-Ginsenoside Rh2 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside 3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol 3β-(β-D-Glucopyranosyl GINSENOSIDE Rh2(SH) Ginsenoside Rh2 ,98% Natural Plant Extracts Ginsenoside Rh2 HPLC 15% 50% 98% 78214-33-2 2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl Ginsenoside Rh2 USP/EP/BP (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol Ginsenoside Rk1&Rh2&Rg3 GINSENOSIDE Rh2 (S-FORM)(AS) 25mg Ginsenoside Rh2-RM Ginsenoside Rh2(AS) Ginsenoside Rh2(P) 10% Ginseng extract inclusion complex 20(S)-Ginsenoside Rh2, Active component of red ginseng Ginsenoside Rh2, 10 mM in DMSO GINSENOSIDE Rh2 (S-FORM) Ginsenoside Rh2 (Standard) 20(S)-Rh2 Rh2 78214-33-2 78274-33-2 C36H62O8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors Ginsenoside series 78214-33-2