DDP-38003 (dihydrochloride)
- CAS No.
- 1831167-98-6
- Chemical Name:
- DDP-38003 (dihydrochloride)
- Synonyms
- DDP38003;DDP-38003 2HCl;DDP-38003 (dihydrochloride);DDP-38003 dihydrochloride, 10 mM in DMSO;DDP 38003 DIHYDROCHLORIDE; DDP38003 DIHYDROCHLORIDE;N-{4-[(1S,2R)-2-Aminocyclopropyl]phenyl}-4-(4-methyl-1-piperazinyl)benzamide dihydrochloride;Benzamide,N-[4-[(1S,2R)-2-aminocyclopropyl]phenyl]-4-(4-methyl-1-piperazinyl)-,hydrochloride(1:2)
- CBNumber:
- CB03167607
- Molecular Formula:
- C21H27ClN4O
- Molecular Weight:
- 386.92
- MDL Number:
- MFCD30718603
- MOL File:
- 1831167-98-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| DDP-38003dihydrochloride >98% | DC10413 | 100mg | $900 |
| DDP-38003dihydrochloride >98% | DC10413 | 1g | $3600 |
DDP-38003 (dihydrochloride) Chemical Properties,Uses,Production
Description
DDP-38003 2HCl is an orally available inhibitor of histone lysine-specific demethylase 1A (LSD1).
Uses
DDP-38003 dihydrochloride is an novel, orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with an IC50 of 84 nM[1].
in vivo
DDP-38003 exhibits in vivo efficacy after oral administration, determining a 62% increased survival in mouse leukemia models with evidence of KDM1A inhibition. The half life of DDP-38003 is 8 h. A significant dose dependent increase of mice survival is obtained by DDP-38003 treatment. The survival rate increases 35% and 62% at the dose of 11.25 and 22.50 mg/kg, respectively. DDP-38003 is a potential oral anticancer agent[1].
IC 50
KDM1/LSD1
References
[1] Vianello P, et al. Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent. J Med Chem. 2016 Feb 25;59(4):1501-17. DOI:10.1021/acs.jmedchem.5b01209
DDP-38003 (dihydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
DDP-38003 (dihydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8612 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 646 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 7999 | 62 |
| Chuzhou KeMail Chemical Technology Co., Ltd | 0550-5196001 15000891977 | wj520wjxby@126.com | China | 1946 | 55 |
View Lastest Price from DDP-38003 (dihydrochloride) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | DDP-38003 dihydrochloride
1831167-98-6
|
US $61.00-240.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-20 | DDP-38003 dihydrochloride
1831167-98-6
|
US $61.00-240.00 / mg | 99.76% | 10g | TargetMol Chemicals Inc. |
-
- DDP-38003 dihydrochloride
1831167-98-6
- US $61.00-240.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
-
- DDP-38003 dihydrochloride
1831167-98-6
- US $61.00-240.00 / mg
- 99.76%
- TargetMol Chemicals Inc.
