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BAFILOMYCIN C1

BAFILOMYCIN C1 structure

CAS No.: 88979-61-7

Chemical Name:: BAFILOMYCIN C1

Synonyms: L-681110A1;BAFILOMYCIN C1;Antibiotic L-681110A1;Bafilomycin C-1,Bafilomycin C1;2-Demethyl-2-methoxy-24-methylhygrolidin;Bafilomycin C1, from Streptomyces griseus;Bafilomycin C1, Vacuolar-type H+-ATPase inhibitor.;2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester

CBNumber:: CB0320023

Molecular Formula:: C39H60O12

Molecular Weight:: 720.89

MDL Number:: MFCD00904461

MOL File:: 88979-61-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

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BAFILOMYCIN C1 Properties

storage temp.	Store at -20°C
solubility	DMSO: 5 mg/ml; Methanol: 5 mg/ml
form	White to light-brown solid.
color	Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

NFPA 704

	0
4		0

BAFILOMYCIN C1 price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	19625	Bafilomycin C1 ≥95%	88979-61-7	1mg	$90	2026-04-30	Buy
Cayman Chemical	19625	Bafilomycin C1 ≥95%	88979-61-7	5mg	$422	2026-04-30	Buy
Usbiological	B0003-72	Bafilomycin C1 (Antibiotic L-681,110A1) ~95%(HPLC)	88979-61-7	1mg	$426	2026-06-03	Buy
Usbiological	207085	Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin) ≥98%(HPLC)	88979-61-7	1mg	$482	2026-06-03	Buy
Biosynth	NDA97961	Bafilomycin C1	88979-61-7	5mg	$1307.75	2026-06-04	Buy

Product number	Packaging	Price	Buy
19625	1mg	$90	Buy
19625	5mg	$422	Buy
B0003-72	1mg	$426	Buy
207085	1mg	$482	Buy
NDA97961	5mg	$1307.75	Buy

BAFILOMYCIN C1 Chemical Properties, Uses, Production

Uses

Bafilomycin C1 is a member of a potent family of macrocyclic lactones. Bafilomycin C1 shares a similar mode of action and activity as its more accessible A1 analogue. Bafilomycin C1 is broadly active against bacteria, fungi, insects, nematodes and cestodes. Bafilomycin C1 has attracted interest as a potential agent for treating osteoporosis. The presence of the fumarate group provides an ideal ligand for affinity chromatography of V-ATPase.

Uses

Bafilomycin C1 is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases). It blocks these pumps in mammalian, plant, or fungal cells, preventing proton transport and compartment acidification. Bafilomycin C1 has been shown to have angiostatic activity in the chick chorioallantoic membrane assay. It has also been used, when coupled to cellulose, to purify V-ATPases.[Cayman Chemical]

in vivo

Bafilomycin C1 (subcutaneous injection; 0.2 mg/kg; 20 days) retards the tumor growth without apparent adverse reactions or side effects in nude mice model^[1].

Animal Model:	BALB/c nude mice (weighing 18-20 g) subcutaneous injected by SMMC7721 cell suspension (5×10⁶ cells/100 μL)^[2]
Dosage:	0.2 mg/kg
Administration:	Subcutaneous injection; 20 days
Result:	Suppressed tumor growth of SMMC7721 tumor xenografts.

IC 50

Macrolide

storage

+4°C

BAFILOMYCIN C1 Preparation Products And Raw materials

Raw materials

Preparation Products

BAFILOMYCIN C1 Suppliers

Global Suppliers ( 59)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9799	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4578	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4372	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Hefei fuya biotechnology co. LTD	18096409024	sales02@foreversyn.com	China	1934	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11123	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8857	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8137	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44871	58

Supplier	Advantage
Shanghai EFE Biological Technology Co., Ltd.	58
Lynnchem	58
Novachemistry	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Hefei fuya biotechnology co. LTD	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Meng Cheng Technology (Shanghai) Co., LTD	58
MedBioPharmaceutical Technology Inc	58
Energy Chemical	58

View Latest Price from BAFILOMYCIN C1 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-16	Bafilomycin C1 88979-61-7	$287.00-1380.00			10g	TargetMol Chemicals Inc.
	2025-12-22	Bafilomycin C1 88979-61-7				10g	TargetMol Chemicals Inc.

Bafilomycin C1
88979-61-7
$287.00-1380.00
TargetMol Chemicals Inc.

Bafilomycin C1
88979-61-7
TargetMol Chemicals Inc.

88979-61-7 (BAFILOMYCIN C1) Related Search:

HUMAN MDC (CCL22) Butyl fumarate mono Butyl sorbate Monoisopropyl fumarate 2,4-Decadienoic acid methyl ester

Ethyl-2,4-decadienoate BAFILOMYCIN C1 Monoethyl fumarate

1of2

2-Demethyl-2-methoxy-24-methylhygrolidin Antibiotic L-681110A1 L-681110A1 BAFILOMYCIN C1 2-Butenedioic acid (2E)-, 1-[(2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethyl)-2H-pyran-4-yl] ester Bafilomycin C1, from Streptomyces griseus Bafilomycin C-1,Bafilomycin C1 Bafilomycin C1, Vacuolar-type H+-ATPase inhibitor. 88979-61-7 C39H60O12