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4-Isopropylphenol

4-Isopropylphenol structure

CAS No.: 99-89-8

Chemical Name:: 4-Isopropylphenol

Synonyms: P-CUMENOL;p-Isopropylphenol;4-(1-methylethyl)-Phenol;NSC 1888;prodox133;Australol;Prodox 133;4-Isopropylphe;4-HYDROXYCUMOL;p-Hydroxycumene

CBNumber:: CB0320977

Molecular Formula:: C9H12O

Molecular Weight:: 136.19

MDL Number:: MFCD00002372

MOL File:: 99-89-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:36:40

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4-Isopropylphenol Properties

Melting point	59-61 °C (lit.)
Boiling point	212-213 °C (lit.)
Density	0.9900
vapor density	>1 (vs air)
refractive index	1.5228
FLAVIS Number	04.073 \| 4-Isopropylphenol
Flash point	108°C
storage temp.	Store at +2°C to +8°C.
solubility	Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
pka	10.19±0.13(Predicted)
form	Crystalline Mass or Crystals
color	White to beige-brown
Odor	at 1.00 % in dipropylene glycol. woody warm spicy medicinal
Odor Type	woody
Water Solubility	Slightly soluble in water, soluble in ethanol and ethyl ether.
BRN	1363564
Cosmetics Ingredients Functions	PERFUMING
InChI	1S/C9H12O/c1-7(2)8-3-5-9(10)6-4-8/h3-7,10H,1-2H3
InChIKey	YQUQWHNMBPIWGK-UHFFFAOYSA-N
SMILES	CC(C)c1ccc(O)cc1
LogP	2.900
CAS DataBase Reference	99-89-8(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances	ISOPROPYLPHENOL, P-
EWG's Food Scores	1
FDA UNII	9F59JOO816
NIST Chemistry Reference	Phenol, 4-(1-methylethyl)-(99-89-8)
EPA Substance Registry System	p-Isopropylphenol (99-89-8)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H314-H317-H412

Precautionary statements

P501-P273-P272-P260-P270-P264-P280-P362+P364-P303+P361+P353-P333+P313-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405

PPE

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Codes

Risk Statements

22-34-43-52/53

Safety Statements

26-36/37/39-45-61

RIDADR

UN 2430 8/PG 3

WGK Germany

RTECS

SL5950000

Hazard Note

Corrosive/Harmful

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29071900

Storage Class

8B - Non-combustible corrosive hazardous materials

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Skin Corr. 1B

REACH Registrations

Active

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
3		0

4-Isopropylphenol price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	175404	4-Isopropylphenol 98%	99-89-8	5g	$34.5	2026-04-30	Buy
Sigma-Aldrich	PHR9185	4-Isopropylphenol certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	99-89-8	50 mg	$348	2026-04-30	Buy
Sigma-Aldrich	175404	4-Isopropylphenol 98%	99-89-8	100g	$126	2026-04-30	Buy
TCI Chemical	I0262	4-Isopropylphenol >99.0%(GC)	99-89-8	25g	$65	2026-04-30	Buy
TCI Chemical	I0262	4-Isopropylphenol >99.0%(GC)	99-89-8	100g	$169	2026-04-30	Buy

Product number	Packaging	Price	Buy
175404	5g	$34.5	Buy
PHR9185	50 mg	$348	Buy
175404	100g	$126	Buy
I0262	25g	$65	Buy
I0262	100g	$169	Buy

4-Isopropylphenol Chemical Properties,Uses,Production

Chemical Properties

WHITE TO BEIGE CRYSTALLINE SOLID

Uses

4-Isopropylphenol is an Impurity of Propofol (P829750).

Uses

4-Isopropylphenol was used in the synthesis of vinyl compounds. It is used as a flavor & fragrance agent in cosmetics.

Definition

ChEBI: 4-isopropylphenol is a member of the class of phenols that is phenol which is carrying an isopropyl group at position 4. It has a role as a flavouring agent. It derives from a hydride of a cumene.

Production Methods

4-Isopropylphenol is produced:
1) by isolation from Eucalyptus polybractea oil.
2) from Magnesium para-iso-propylphenyl-bromide by air oxidation.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 3889, 1949 DOI: 10.1021/ja01180a005
Synthesis, p. 396, 1978 DOI: 10.1055/s-1978-24762

General Description

Sonochemical degradation of 4-Isopropylphenol has been studied.

4-Isopropylphenol synthesis

Synthesis of 4-Isopropylphenol from p-Isopropylphenetole

4-Isopropylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-Isopropenylphenol 4-Isopropylphenoxyacetic acid 3-Formyl-6-isopropylchromone 4-Isopropylcatechol 2-(4-Isopropylphenoxy)benzaldehyde

4-Isopropylphenol Suppliers

Global( 226)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan hongde yuexin pharmaceutical technology co. LTD	027-83855391 13657260109	2143879032@QQ.com	China	1000	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66
Nanjing Datang Chemical Co., Ltd	025-85431992 13951889900	vip@chemdatang.com	China	100	66
Shanghai Longsheng chemical Co.,Ltd.	58099637 13585536065	sales@shlschem.com	China	9880	59
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15350	60

Supplier	Advantage
Wuhan hongde yuexin pharmaceutical technology co. LTD	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66
Nanjing Datang Chemical Co., Ltd	66
Shanghai Longsheng chemical Co.,Ltd.	59
Shanghai Hanhong Scientific Co.,Ltd.	64
Chemsky (shanghai) International Co.,Ltd	60

View Lastest Price from 4-Isopropylphenol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	4-Isopropylphenol 99-89-8		20kg	99%	20 tons	Qingdao RENAS Polymer Material Co., Ltd.
2026-03-20	4-Isopropylphenol 99-89-8	$10.00	1kg	99%	100 mt	Hebei Chuanghai Biotechnology Co., Ltd
2021-08-12	4-Isopropylphenol 99-89-8	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

4-Isopropylphenol
99-89-8
$0.00
99%
Qingdao RENAS Polymer Material Co., Ltd.

4-Isopropylphenol
99-89-8
$10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-Isopropylphenol
99-89-8
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-Isopropylphenol Spectrum

4-Isopropylphenol(99-89-8)MS 4-Isopropylphenol(99-89-8)¹HNMR 4-Isopropylphenol(99-89-8)¹³CNMR 4-Isopropylphenol(99-89-8)IR1 4-Isopropylphenol(99-89-8)IR2 4-Isopropylphenol(99-89-8)IR3 4-Isopropylphenol(99-89-8)Raman

99-89-8(4-Isopropylphenol)Related Search:

Diisopropylamine Cumene Cuminaldehyde N,N-Diisopropylethylamine 4-Isopropylaniline

4'-Isopropylacetophenone 4-ISOPROPYLBENZENESULFONYL CHLORIDE Chloromethyl isopropyl carbonate Lithium diisopropylamide 4-Isopropylbenzoic acid

2-Isopropoxyphenol Propofol Phenol 2-Isopropylphenol 3-Isopropylphenol

2,4-Diisopropylphenol 3,6-Diisopropyl-1,2-benzenediol 2,6-Diisopropyl-1,4-benzoquinone

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Phenol,p-isopropyl- p-isopropyl-pheno Prodox 133 Australol Phenol, p-isopropyl- phenol,4-(1-methylethyl)- Propofol EP Impurity H Thymol Impurity 12 Propofol Impurity 8（Propofol EP Impurity H） prodox133 p-lsopropylphenol p-Hydroxycumene PARA-ISOPROPYLPHENOL 4-ISOPROPYLPHENOL 98+% 4-Isopropylphenol 98% p-Cumenol, 4-Hydroxycumene, 4-(Prop-2-yl)phenol 4-Isopropylphenol, 98% 100GR NSC 1888 p-Cumenol 4-Hydroxycumene 4-Isopropylphe 4'-HYDROXYCUMENE 4-HYDROXYCUMENE 4-HYDROXYCUMOL 4-ISOPROPYLPHENOL 1-Hydroxy-4-isopropylbenzene 4-(1-methylethyl)-pheno 4-(1-Methylethyl)phenol 4-Isopropylphenol> Hydroquinone Impurity 3 4-(1-methylethyl)-Phenol P-CUMENOL p-Isopropylphenol 99-89-8 Organic Building Blocks Oxygen Compounds Phenols Building Blocks Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals