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mPEG-SH

mPEG-SH structure

CAS No.: 134874-49-0

Chemical Name:: mPEG-SH

Synonyms: PEG-THIOL;mPEG-SH;mPEG2K-SH;mPEG12-HS;mPEGn-thiol;mPEG12-thiol;m-PEG550-thiol;m-PEG750-thiol;m-PEG1000-thiol;m-PEG2000-thiol

CBNumber:: CB0324197

Molecular Formula:: C25H52O12S

Molecular Weight:: 576.73818

MDL Number:: MFCD00803682

MOL File:: 134874-49-0.mol

MSDS File:: SDS

Last updated:2026-09-12 18:48:07

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mPEG-SH Properties

storage temp.	2-8°C, stored under nitrogen
form	Solid
color	White to off-white
InChI	InChI=1S/C25H52O12S/c1-26-2-3-27-4-5-28-6-7-29-8-9-30-10-11-31-12-13-32-14-15-33-16-17-34-18-19-35-20-21-36-22-23-37-24-25-38/h38H,2-25H2,1H3
InChIKey	MXDXXEVQFMVAIA-UHFFFAOYSA-N
SMILES	C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCS)OC
UNSPSC Code	51171641
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H335-H319
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
WGK Germany	3
Storage Class	11 - Combustible Solids

mPEG-SH price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	743011	O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 10,000	134874-49-0	250mg	$219	2026-04-30	Buy
Sigma-Aldrich	743011	O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol 10,000	134874-49-0	1g	$503	2026-04-30	Buy
Biosynth	DPG-6120	m-dPEG®12-Thiol	134874-49-0	100mg	$413	2026-06-04	Buy
Biosynth	DPG-6120	m-dPEG®12-Thiol	134874-49-0	1000mg	$1400	2026-06-04	Buy
ChemScene	CS-0889977	m-PEG550-thiol ≥98%	134874-49-0	1g	$130	2026-06-04	Buy

Product number	Packaging	Price	Buy
743011	250mg	$219	Buy
743011	1g	$503	Buy
DPG-6120	100mg	$413	Buy
DPG-6120	1000mg	$1400	Buy
CS-0889977	1g	$130	Buy

mPEG-SH Chemical Properties, Uses, Production

Description

m-PEG12-thiol is a PEG linker containing a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG-thiol (MW 1000) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

References

[1] Li J, et al. Simple and Rapid Functionalization of Gold Nanorods with Oligonucleotides Using an mPEG-SH/Tween 20-Assisted Approach. Langmuir. 2015 Jul 21;31(28):7869-76. DOI:10.1021/acs.langmuir.5b01680

mPEG-SH Preparation Products And Raw materials

Raw materials

Preparation Products

mPEG-SH Suppliers

Global Suppliers ( 101)

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Baostai Medical Materials Co. LTD	0531-95836715 15550029578	958367155@qq.com	China	82	58
Shanghai Toyang Biotechnology Co., LTD	021-59555769 13524932310	1405894150@qq.com	China	1082	58
iBioMat	88690234 19106834332	ibmt@ibiomat.com.cn	China	58	58
Jilin Chuangli Biotechnology Co.,Ltd.	19396231124 19396231124	317100529@qq.com	China	798	58
	19011298796 19011298796	17816380947@139.com	China	474	58
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
Nanjing Norris-Pharm Technology Co., Ltd	13901585132	sales@norris-pharm.com	China	8869	55
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60

Supplier	Advantage
Shandong Baostai Medical Materials Co. LTD	58
Shanghai Toyang Biotechnology Co., LTD	58
iBioMat	58
Jilin Chuangli Biotechnology Co.,Ltd.	58
	58
Beijing HwrkChemical Technology Co., Ltd	55
Adamas Reagent, Ltd.	59
T&W GROUP	58
Nanjing Norris-Pharm Technology Co., Ltd	55
Bide Pharmatech Ltd.	60

View Latest Price from mPEG-SH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	MPEG-SH 134874-49-0		1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-07-22	MPEG-SH 134874-49-0		1KG	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd
2026-07-15	m-PEG12-Thiol	$35.00-53.00			10g	TargetMol Chemicals Inc.

MPEG-SH
134874-49-0
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

MPEG-SH
134874-49-0
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

m-PEG12-Thiol
$35.00-53.00
TargetMol Chemicals Inc.

mPEG-SH Spectrum

MPEG-SH(134874-49-0)¹HNMR

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O-(2-MERCAPTOETHYL)-O'-METHYLPOLYETHYLENE GLYCOL 5,000 MERCAPTO POLYETHYLENE GLYCOL 5,000 MONOMETHYL ETHER MPEGn-SH 2K, 5K, 10K, 20K O-(2-Mercaptoethyl)-O′-methylpolyethylene glycol Polyethylene glycol 2-mercaptoethyl methyl ether O-(2-Mercaptoethyl)-O'-methylpolyethylene glycol 2,000 Poly(ethylene glycol) methyl ether thiol (Mn 2000) mPEG12-thiol O-(2-Mercaptoethyl)-O'-methylpolyethylene glycol 10,000 MEO-DPEG(TM)(12)-SH mPEG-SH mPEG2K-SH mPEG-SH,MW:20000 m-PEG-thiol (MW 10000) m-PEG-thiol (MW 350) m-PEG-thiol (MW 750) m-PEG-thiol (MW 550) m-PEG-thiol (MW 1000) 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol m-dPEG???-Thiol (QBD-10794) MPEG-SH,MW:10000 mPEGn-thiol PEG-THIOL Methoxypoly(ethylene glycol)Acetamide Ethanethiol m-PEG1000-thiol m-PEG550-thiol m-PEG750-thiol m-PEG2000-thiol m-PEG10000-thiol mPEG12-HS 134874-49-0 Polydispersed PEG peg